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The map label for this gene is focC [H]

Identifier: 218704977

GI number: 218704977

Start: 1789515

End: 1790234

Strand: Reverse

Name: focC [H]

Synonym: ECUMN_1760

Alternate gene names: 218704977

Gene position: 1790234-1789515 (Counterclockwise)

Preceding gene: 218704978

Following gene: 218704976

Centisome position: 34.41

GC content: 45.42

Gene sequence:

>720_bases
ATGCATCAGATGCAAACTACGCGTACCCCCTACTCTATTTCCTTTATGGCGACAGTGTTACTTTTATTGCTCTTTGCTTG
CCATAGCACCATTGCCAACGCAGCTGTCGCACTGGGTGCGACGCGGGTAATTTATCCGGCAAACCAGAAACAGGTTTTAT
TGCCTGTCACGAATAATGATCCTGCCAGTGTCTATCTCATTCAGTCATGGATAGAAAATGCAGGTGACCAAAAAGACACC
CAGTTTGTCATTACGCCACCGCTTTTTTCCATGCAAGGTAAAAAAGAGAATACGCTGCGGATAATCAACGCCACTAATCA
TCAGTTACCAGGCGACCGTGAAAGCCTGTTCTGGGTTAATGTTAAAGCTATTCCTGCTATGGAAAAAGATCAGAAGAATG
AGAATACATTACAGCTGGCAATTATTAGCCGCATAAAAATGTTTTATCGCCCCACGAACCTGGCAATGGCACCTGAAGAA
GCGCCTGCAATGCTTCGGTTTCGTCGCAGCGGCAGCAAACTCACTCTTATTAATCCAACGCCCTACTTCATTACCGTAAC
AAATATGAAAGCAGGAAATAGCAATCTCCCAAACACCATGGTGCCGCCAAAAGGTGAAGTATCGGTGGATATCCCGCATG
CTGCAACCGGGGATATCAGTTTTCAGACGATCAATGATTACGGTGCATTAACTCCGCGTATTAAGGCAACCATGCAGTAA

Upstream 100 bases:

>100_bases
GCATTAAGTCTGGAAACCCGGCGAGTCGCCAATGTATTAGCAATATTTACTGATTGTCTGATGTAACGGTTTTCCCGCTT
ATCCTCTTAACACATGGAGA

Downstream 100 bases:

>100_bases
GCCAGTGACCTAATTAATAATAAACTCAATCGGAATTAATAATGACAGCCTTTCGTGCCGCATTTAAGGCATATCGTATG
CATCAGGTGTTACTACTGCC

Product: Periplasmic chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MHQMQTTRTPYSISFMATVLLLLLFACHSTIANAAVALGATRVIYPANQKQVLLPVTNNDPASVYLIQSWIENAGDQKDT
QFVITPPLFSMQGKKENTLRIINATNHQLPGDRESLFWVNVKAIPAMEKDQKNENTLQLAIISRIKMFYRPTNLAMAPEE
APAMLRFRRSGSKLTLINPTPYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAATGDISFQTINDYGALTPRIKATMQ

Sequences:

>Translated_239_residues
MHQMQTTRTPYSISFMATVLLLLLFACHSTIANAAVALGATRVIYPANQKQVLLPVTNNDPASVYLIQSWIENAGDQKDT
QFVITPPLFSMQGKKENTLRIINATNHQLPGDRESLFWVNVKAIPAMEKDQKNENTLQLAIISRIKMFYRPTNLAMAPEE
APAMLRFRRSGSKLTLINPTPYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAATGDISFQTINDYGALTPRIKATMQ
>Mature_239_residues
MHQMQTTRTPYSISFMATVLLLLLFACHSTIANAAVALGATRVIYPANQKQVLLPVTNNDPASVYLIQSWIENAGDQKDT
QFVITPPLFSMQGKKENTLRIINATNHQLPGDRESLFWVNVKAIPAMEKDQKNENTLQLAIISRIKMFYRPTNLAMAPEE
APAMLRFRRSGSKLTLINPTPYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAATGDISFQTINDYGALTPRIKATMQ

Specific function: Involved in the biogenesis of the F1C fimbriae [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1790771, Length=233, Percent_Identity=59.656652360515, Blast_Score=288, Evalue=2e-79,
Organism=Escherichia coli, GI1786743, Length=217, Percent_Identity=45.6221198156682, Blast_Score=200, Evalue=9e-53,
Organism=Escherichia coli, GI1787171, Length=218, Percent_Identity=41.2844036697248, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789532, Length=217, Percent_Identity=36.8663594470046, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786936, Length=225, Percent_Identity=34.2222222222222, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1786333, Length=233, Percent_Identity=32.1888412017167, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1788677, Length=201, Percent_Identity=30.8457711442786, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788428, Length=220, Percent_Identity=30, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI87081806, Length=227, Percent_Identity=30.8370044052863, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082203, Length=220, Percent_Identity=30, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 26517; Mature: 26517

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQMQTTRTPYSISFMATVLLLLLFACHSTIANAAVALGATRVIYPANQKQVLLPVTNND
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCC
PASVYLIQSWIENAGDQKDTQFVITPPLFSMQGKKENTLRIINATNHQLPGDRESLFWVN
CCEEEEEEHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEE
VKAIPAMEKDQKNENTLQLAIISRIKMFYRPTNLAMAPEEAPAMLRFRRSGSKLTLINPT
EEECCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEECCCCCCHHHEEECCCCEEEEECCC
PYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAATGDISFQTINDYGALTPRIKATMQ
CEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCEEEECC
>Mature Secondary Structure
MHQMQTTRTPYSISFMATVLLLLLFACHSTIANAAVALGATRVIYPANQKQVLLPVTNND
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEEEEECCCC
PASVYLIQSWIENAGDQKDTQFVITPPLFSMQGKKENTLRIINATNHQLPGDRESLFWVN
CCEEEEEEHHHHCCCCCCCCEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEEEEE
VKAIPAMEKDQKNENTLQLAIISRIKMFYRPTNLAMAPEEAPAMLRFRRSGSKLTLINPT
EEECCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCEECCCCCCHHHEEECCCCEEEEECCC
PYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAATGDISFQTINDYGALTPRIKATMQ
CEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]