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The map label for this gene is yicI [C]

Identifier: 218704239

GI number: 218704239

Start: 1034718

End: 1037093

Strand: Reverse

Name: yicI [C]

Synonym: ECUMN_1005

Alternate gene names: 218704239

Gene position: 1037093-1034718 (Counterclockwise)

Preceding gene: 218704240

Following gene: 218704237

Centisome position: 19.94

GC content: 55.26

Gene sequence:

>2376_bases
ATGGATGTAAACATGAAAACGCTGAAAAACTGGACCCTGCACAAACAGTCTGCCCACCACGTTGAACTGCTGGTCGATGG
CCAGCATATCCTGTGCCTGTACGTGCTGGAAGAAAATCTGTTCCGCGTGCTGTTAAAACGCAAAGGCGAGCTGGCGCTGG
ATCGCACCTGGAGCATTGCTCCGGCGCAGGATGTGCCATGGGAAGGGCGCAGCCGCGAAGATCTCAGCGGCTTTAGCCTG
CCCGCGTGGACATTGATCCAGCACGACGACACCGTGGTTATCGCCACCGAGTCACTGCGTGCCACCGTTCACCAGCCGCT
GTGGCTGGAGTGGCACTATCGTAACAACGAAGGCGAATGGCTGCCGTTGGTGAATGACCGCCCGACCAGCGCTTATCTGC
TGAATGCCCACGGCGACGGCGTGGCGCACTATCAGAGCCGTCGTAAAGATGAACGCTTTTATGGCCTCGGAGATAAAGCC
GGCGACCTGCAACGCAACGGTAAACGTTACGAGATGCGTAACCTCGACGCGATGGGCTACAACGCCGTGAGTACTGACCC
GTTGTACAAACACATTCCATTCACCATCACCCGCCGCGATGACATTAGCTTCGGCCTGTTTTATGACAACCTCAGCAGCT
GCTGGCTGGATCTGGGCAACGAGATCGACAACTACCACACCGCCTATCGCCGCTGGCAGGCGGAAGCGGGTGATATCGAC
TACTACCTGTTTACCGGCGAACGCGTACTTGATATCACCAAAGCCTTCGTACGCCTGACCGGCAAAACCCTGTTCGGACC
GAAATGGAGCCTGGGCTACAGCGGTTCAACTATGCACTACACCGATGCGCCGGACGCACAAAATCAGTTGATGAACTTTA
TCCGCCTGTGTGAAGAACATGCAATTCCCTGCGATTCGTTCCAGCTCTCATCCGGTTATACCTCAATTAACGGCAAACGC
TATGTGTTCAACTGGAACTACGAAAAAGTGCCGCAGCCGAAAGTGATGAGCCAGGCATTTCACAATGCTGGTTTGCACCT
GGCCGCCAATATCAAGCCGTGCCTGTTGCAGGATCACCCACGCTATAACGAAGTGGCAGAAAGAGGACTATTCATCCGTG
ATTCAGAAACAGATGAACCAGAACGTTCCAGCTTCTGGGATGACGAAGGTTCTAACCTCGACTTTACTAATCCGCAGACC
ATCCAGTGGTGGCAGGAAGGCGTGACCACACAGCTTCTGGAGATGGGTATCGACTCCACCTGGAACGACAACAACGAATT
CGAAGTATGGGACGGTGAAGCACGCTGTCACGGCTTTGGTCAGACGATCGCGATCAAACATATTCGCCCAGTGATGCCAC
TGCTGATGATGCGAGCCTCGATGGAAGCCCAGCAGCGTTTCGCTCCGGAAAAACGTCCGTACTTGATCTCCCGCTCCGGC
TGCGCGGGAATGCAGCGCTACGTGCAGACCTGGAGTGGCGATAACCGCACTAGCTGGGACACTCTGCGCTACAACACCCG
CATGGGTCTGGGGATGAGCCTCTCCGGGCTGTATAACCTCGGTCACGACGTCGGCGGTTTCTCCGGTGATAAGCCGGACC
CGGAACTGTTTGTACGCTGGGTACAAAACGGCGTGATGCATCCGCGCTTTACGATTCACTCATGGAACGATGACCATACC
GTAAACGAACCGTGGATGTATCCGGGCGTCACTCCGGCGATCCGCAGCGCTATTGAGTTGCGCTATCGCCTGCTGCCCTA
CTTTTATACCCTGATGTGGCAGGCATACGCCGATGATGAACCAATGCTACGTCCGACTTTCCTTGACCACGAGCACGACG
TTCAGACTTTTGAAGAGTGTGATGACTTCCTGCTTGGTCGCGATATTTTGGTTGCCAGCGTCGTAGAGCAAGGCGAGCGC
CAGCGCCGTGTATGGCTGCCAGATAACGAAACTGGCTGGTACGATTTCTACAACGGCGAATGGTTCAGTGGCGGTCAGTG
GATCACCCTCGACGCACCGCTGGAGAAACTGCCGCTGATGGTGCGTGCCGGGGCTGGTCTACCGCTCAGCAAACGCATCA
CCTATGTGAGCGCAGAACAAGACGATACCCGCGAACTGAAACTGTTCCCGCTGAAAGGTGTGGGCACAACGTCCGGCCTG
CTGTTTGAAGACGATGGCGAAAGCTGGGGCTACCAAACTGGTAATGCGCTTTGGGTGGAATGGGAAATGGTTTGCGATGG
GGCGACCATCAACCTGAAAGTCAACGCGCGCGGGGATTATCGACCTGCATGGAGTGCACTGAAAGTGTCATTACCAGTGG
AAGAAAAACGCACGCTGCTGGTCAATGGTGTTGAAGGGAGTGAATGGATGCGTTAA

Upstream 100 bases:

>100_bases
GCTTTAACCCCCTGTTTATCGCCATGGGCTTCTTTGACCTGATTGGTGCTTTCTTCCTGGTCACCTTTATTGCTGAACGT
CGCGCAAAACGCGCCTGAGA

Downstream 100 bases:

>100_bases
ATCATTACCGGGGCCGGGAGGCGACTGCGCCTTACCCGGTCCAGCCATCGAATCCTTTACCTCAGTATTTCACGCTGCAG
GAAGGCAGCAAACCTGTAAA

Product: putative glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 791; Mature: 791

Protein sequence:

>791_residues
MDVNMKTLKNWTLHKQSAHHVELLVDGQHILCLYVLEENLFRVLLKRKGELALDRTWSIAPAQDVPWEGRSREDLSGFSL
PAWTLIQHDDTVVIATESLRATVHQPLWLEWHYRNNEGEWLPLVNDRPTSAYLLNAHGDGVAHYQSRRKDERFYGLGDKA
GDLQRNGKRYEMRNLDAMGYNAVSTDPLYKHIPFTITRRDDISFGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDID
YYLFTGERVLDITKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEEHAIPCDSFQLSSGYTSINGKR
YVFNWNYEKVPQPKVMSQAFHNAGLHLAANIKPCLLQDHPRYNEVAERGLFIRDSETDEPERSSFWDDEGSNLDFTNPQT
IQWWQEGVTTQLLEMGIDSTWNDNNEFEVWDGEARCHGFGQTIAIKHIRPVMPLLMMRASMEAQQRFAPEKRPYLISRSG
CAGMQRYVQTWSGDNRTSWDTLRYNTRMGLGMSLSGLYNLGHDVGGFSGDKPDPELFVRWVQNGVMHPRFTIHSWNDDHT
VNEPWMYPGVTPAIRSAIELRYRLLPYFYTLMWQAYADDEPMLRPTFLDHEHDVQTFEECDDFLLGRDILVASVVEQGER
QRRVWLPDNETGWYDFYNGEWFSGGQWITLDAPLEKLPLMVRAGAGLPLSKRITYVSAEQDDTRELKLFPLKGVGTTSGL
LFEDDGESWGYQTGNALWVEWEMVCDGATINLKVNARGDYRPAWSALKVSLPVEEKRTLLVNGVEGSEWMR

Sequences:

>Translated_791_residues
MDVNMKTLKNWTLHKQSAHHVELLVDGQHILCLYVLEENLFRVLLKRKGELALDRTWSIAPAQDVPWEGRSREDLSGFSL
PAWTLIQHDDTVVIATESLRATVHQPLWLEWHYRNNEGEWLPLVNDRPTSAYLLNAHGDGVAHYQSRRKDERFYGLGDKA
GDLQRNGKRYEMRNLDAMGYNAVSTDPLYKHIPFTITRRDDISFGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDID
YYLFTGERVLDITKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEEHAIPCDSFQLSSGYTSINGKR
YVFNWNYEKVPQPKVMSQAFHNAGLHLAANIKPCLLQDHPRYNEVAERGLFIRDSETDEPERSSFWDDEGSNLDFTNPQT
IQWWQEGVTTQLLEMGIDSTWNDNNEFEVWDGEARCHGFGQTIAIKHIRPVMPLLMMRASMEAQQRFAPEKRPYLISRSG
CAGMQRYVQTWSGDNRTSWDTLRYNTRMGLGMSLSGLYNLGHDVGGFSGDKPDPELFVRWVQNGVMHPRFTIHSWNDDHT
VNEPWMYPGVTPAIRSAIELRYRLLPYFYTLMWQAYADDEPMLRPTFLDHEHDVQTFEECDDFLLGRDILVASVVEQGER
QRRVWLPDNETGWYDFYNGEWFSGGQWITLDAPLEKLPLMVRAGAGLPLSKRITYVSAEQDDTRELKLFPLKGVGTTSGL
LFEDDGESWGYQTGNALWVEWEMVCDGATINLKVNARGDYRPAWSALKVSLPVEEKRTLLVNGVEGSEWMR
>Mature_791_residues
MDVNMKTLKNWTLHKQSAHHVELLVDGQHILCLYVLEENLFRVLLKRKGELALDRTWSIAPAQDVPWEGRSREDLSGFSL
PAWTLIQHDDTVVIATESLRATVHQPLWLEWHYRNNEGEWLPLVNDRPTSAYLLNAHGDGVAHYQSRRKDERFYGLGDKA
GDLQRNGKRYEMRNLDAMGYNAVSTDPLYKHIPFTITRRDDISFGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDID
YYLFTGERVLDITKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEEHAIPCDSFQLSSGYTSINGKR
YVFNWNYEKVPQPKVMSQAFHNAGLHLAANIKPCLLQDHPRYNEVAERGLFIRDSETDEPERSSFWDDEGSNLDFTNPQT
IQWWQEGVTTQLLEMGIDSTWNDNNEFEVWDGEARCHGFGQTIAIKHIRPVMPLLMMRASMEAQQRFAPEKRPYLISRSG
CAGMQRYVQTWSGDNRTSWDTLRYNTRMGLGMSLSGLYNLGHDVGGFSGDKPDPELFVRWVQNGVMHPRFTIHSWNDDHT
VNEPWMYPGVTPAIRSAIELRYRLLPYFYTLMWQAYADDEPMLRPTFLDHEHDVQTFEECDDFLLGRDILVASVVEQGER
QRRVWLPDNETGWYDFYNGEWFSGGQWITLDAPLEKLPLMVRAGAGLPLSKRITYVSAEQDDTRELKLFPLKGVGTTSGL
LFEDDGESWGYQTGNALWVEWEMVCDGATINLKVNARGDYRPAWSALKVSLPVEEKRTLLVNGVEGSEWMR

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI88900491, Length=615, Percent_Identity=30.4065040650407, Blast_Score=264, Evalue=3e-70,
Organism=Homo sapiens, GI38202257, Length=615, Percent_Identity=30.4065040650407, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI66346737, Length=643, Percent_Identity=28.4603421461897, Blast_Score=259, Evalue=1e-68,
Organism=Homo sapiens, GI119393895, Length=555, Percent_Identity=26.8468468468468, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI119393893, Length=555, Percent_Identity=26.8468468468468, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI119393891, Length=555, Percent_Identity=26.8468468468468, Blast_Score=166, Evalue=1e-40,
Organism=Homo sapiens, GI221316699, Length=635, Percent_Identity=23.1496062992126, Blast_Score=146, Evalue=9e-35,
Organism=Homo sapiens, GI157364974, Length=640, Percent_Identity=23.4375, Blast_Score=144, Evalue=4e-34,
Organism=Homo sapiens, GI310115361, Length=270, Percent_Identity=31.1111111111111, Blast_Score=110, Evalue=5e-24,
Organism=Escherichia coli, GI2367256, Length=556, Percent_Identity=25.1798561151079, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI2367323, Length=379, Percent_Identity=28.2321899736148, Blast_Score=125, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71991189, Length=606, Percent_Identity=28.3828382838284, Blast_Score=232, Evalue=7e-61,
Organism=Caenorhabditis elegans, GI17560800, Length=608, Percent_Identity=28.9473684210526, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17560798, Length=608, Percent_Identity=28.9473684210526, Blast_Score=229, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI32563849, Length=265, Percent_Identity=31.6981132075472, Blast_Score=123, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71985706, Length=262, Percent_Identity=30.1526717557252, Blast_Score=108, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319706, Length=618, Percent_Identity=27.0226537216829, Blast_Score=206, Evalue=8e-54,
Organism=Drosophila melanogaster, GI24643749, Length=612, Percent_Identity=26.6339869281046, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24643753, Length=612, Percent_Identity=26.6339869281046, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24643751, Length=612, Percent_Identity=26.6339869281046, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24643746, Length=612, Percent_Identity=26.6339869281046, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI21357605, Length=612, Percent_Identity=26.6339869281046, Blast_Score=208, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24650054, Length=378, Percent_Identity=24.8677248677249, Blast_Score=76, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 91326; Mature: 91326

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00066 HMG_COA_REDUCTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVNMKTLKNWTLHKQSAHHVELLVDGQHILCLYVLEENLFRVLLKRKGELALDRTWSIA
CCCCHHHHCCCEEECCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHCCCCEEECCEECCC
PAQDVPWEGRSREDLSGFSLPAWTLIQHDDTVVIATESLRATVHQPLWLEWHYRNNEGEW
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEHHHHHHHCCCEEEEEEEECCCCCE
LPLVNDRPTSAYLLNAHGDGVAHYQSRRKDERFYGLGDKAGDLQRNGKRYEMRNLDAMGY
EEEECCCCCCEEEEECCCCCHHHHHHHCCCCCEEECCCCCCCHHHCCCEEEECCCCCCCC
NAVSTDPLYKHIPFTITRRDDISFGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDID
CCCCCCCCHHCCCEEEEECCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEE
YYLFTGERVLDITKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEEH
EEEEECCHHHHHHHHHHHHCCCEECCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHH
AIPCDSFQLSSGYTSINGKRYVFNWNYEKVPQPKVMSQAFHNAGLHLAANIKPCLLQDHP
CCCCCCEEECCCEEECCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCEEECCCC
RYNEVAERGLFIRDSETDEPERSSFWDDEGSNLDFTNPQTIQWWQEGVTTQLLEMGIDST
CHHHHHHCCEEEECCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHCCCCC
WNDNNEFEVWDGEARCHGFGQTIAIKHIRPVMPLLMMRASMEAQQRFAPEKRPYLISRSG
CCCCCCEEEECCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
CAGMQRYVQTWSGDNRTSWDTLRYNTRMGLGMSLSGLYNLGHDVGGFSGDKPDPELFVRW
CHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHH
VQNGVMHPRFTIHSWNDDHTVNEPWMYPGVTPAIRSAIELRYRLLPYFYTLMWQAYADDE
HHCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PMLRPTFLDHEHDVQTFEECDDFLLGRDILVASVVEQGERQRRVWLPDNETGWYDFYNGE
CCCCCEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCCCCCCCEECCCCE
WFSGGQWITLDAPLEKLPLMVRAGAGLPLSKRITYVSAEQDDTRELKLFPLKGVGTTSGL
EECCCEEEEECCCHHHCCEEEECCCCCCHHHCEEEEECCCCCCCCEEEEEECCCCCCCCE
LFEDDGESWGYQTGNALWVEWEMVCDGATINLKVNARGDYRPAWSALKVSLPVEEKRTLL
EEECCCCCCCCCCCCEEEEEEEEEECCEEEEEEEECCCCCCCCCCEEEEECCCCCCCEEE
VNGVEGSEWMR
EECCCCHHCCC
>Mature Secondary Structure
MDVNMKTLKNWTLHKQSAHHVELLVDGQHILCLYVLEENLFRVLLKRKGELALDRTWSIA
CCCCHHHHCCCEEECCCCCEEEEEECCCEEEEEEEHHHHHHHHHHHCCCCEEECCEECCC
PAQDVPWEGRSREDLSGFSLPAWTLIQHDDTVVIATESLRATVHQPLWLEWHYRNNEGEW
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEHHHHHHHCCCEEEEEEEECCCCCE
LPLVNDRPTSAYLLNAHGDGVAHYQSRRKDERFYGLGDKAGDLQRNGKRYEMRNLDAMGY
EEEECCCCCCEEEEECCCCCHHHHHHHCCCCCEEECCCCCCCHHHCCCEEEECCCCCCCC
NAVSTDPLYKHIPFTITRRDDISFGLFYDNLSSCWLDLGNEIDNYHTAYRRWQAEAGDID
CCCCCCCCHHCCCEEEEECCCCEEEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCEE
YYLFTGERVLDITKAFVRLTGKTLFGPKWSLGYSGSTMHYTDAPDAQNQLMNFIRLCEEH
EEEEECCHHHHHHHHHHHHCCCEECCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHH
AIPCDSFQLSSGYTSINGKRYVFNWNYEKVPQPKVMSQAFHNAGLHLAANIKPCLLQDHP
CCCCCCEEECCCEEECCCCEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCEEECCCC
RYNEVAERGLFIRDSETDEPERSSFWDDEGSNLDFTNPQTIQWWQEGVTTQLLEMGIDST
CHHHHHHCCEEEECCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHCCCCC
WNDNNEFEVWDGEARCHGFGQTIAIKHIRPVMPLLMMRASMEAQQRFAPEKRPYLISRSG
CCCCCCEEEECCCCEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
CAGMQRYVQTWSGDNRTSWDTLRYNTRMGLGMSLSGLYNLGHDVGGFSGDKPDPELFVRW
CHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHH
VQNGVMHPRFTIHSWNDDHTVNEPWMYPGVTPAIRSAIELRYRLLPYFYTLMWQAYADDE
HHCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PMLRPTFLDHEHDVQTFEECDDFLLGRDILVASVVEQGERQRRVWLPDNETGWYDFYNGE
CCCCCEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCCCCCCCEECCCCE
WFSGGQWITLDAPLEKLPLMVRAGAGLPLSKRITYVSAEQDDTRELKLFPLKGVGTTSGL
EECCCEEEEECCCHHHCCEEEECCCCCCHHHCEEEEECCCCCCCCEEEEEECCCCCCCCE
LFEDDGESWGYQTGNALWVEWEMVCDGATINLKVNARGDYRPAWSALKVSLPVEEKRTLL
EEECCCCCCCCCCCCEEEEEEEEEECCEEEEEEEECCCCCCCCCCEEEEECCCCCCCEEE
VNGVEGSEWMR
EECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]