Click here to switch to the map view.

The map label for this gene is papC

Identifier: 218702824

GI number: 218702824

Start: 4787118

End: 4789649

Strand: Direct

Name: papC

Synonym: ECIAI39_4589

Alternate gene names: 218702824

Gene position: 4787118-4789649 (Clockwise)

Preceding gene: 218702823

Following gene: 218702825

Centisome position: 93.28

GC content: 52.37

Gene sequence:

>2532_bases
GTGAATCTGGTGATGCGTGGAATGAAAGACAGAATACCTTTTGCAGTCAACAATATTACCTGTGTGATATTGTTGTCTCT
GTTTTGTAACGCAGCCAGTGCCGTTGAGTTTAATACAGATGTACTTGACGCGGCGGACAAGAAAAATATTGACTTCACCC
GTTTTTCAGAAGCTGGTTATGTTCTGCCGGGGCAATATCTTCTGGATGTGATTGTTAACGGGCAAAGTATTTCTCCCGCA
TCGTTACAGATTTCATTTGTTGAACCTCAGTCGTCAGGAGATAAGGCAGAAAAAAAATTGCCACAGGCCTGTCTGACATC
AGATATGGTCAGACTGATGGGGTTAACAGCAGAATCTCTGGATAAAGTTGTTTACTGGCATGATGGTCAGTGTGCGGATT
TTCATGGGTTGCCGGGAGTGGATATTCGTCCTGATACCGGAGCGGGCGTATTACGCATCAATATGCCGCAGGCCTGGCTT
GAGTATTCTGATGCCACCTGGCTGCCTCCCTCACGCTGGGACGACGGCATTCCCGGACTGATGCTGGATTATAACCTCAA
CGGGACGGTTTCCCGTAATTATCAGGGAGGAGACTCTCATCAGTTCAGTTATAACGGGACTGTGGGGGGGAATCTGGGGC
CCTGGCGCCTGCGGGCTGACTATCAGGGAAGCCAGGAGCAGAGCCGCTACAACGGGGAAAAAACGACAAACAGAAATTTC
ACATGGAGTCGCTTTTATCTGTTCCGTGCCATTCCACGATGGCGGGCAAACCTGACGCTGGGCGAGAATAATATCAACTC
AGATATATTCCGGTCATGGAGTTATACGGGAGCCAGCCTGGAAAGCGATGACCGGATGCTGCCACCCAGACTGCGAGGCT
ATGCACCGCAGATTACCGGGATTGCGGAGACTAATGCCCGTGTTGTGGTGTCGCAGCAGGGACGGGTGCTGTACGACTCG
ATGGTCCCCGCAGGGCCATTCAGTATTCAGGACCTGGACAGTTCAGTTCGCGGACGTCTTGATGTTGAGGTTATTGAACA
GAACGGACGGAAGAAAACCTTTCAGGTCGATACGGCCTCGGTTCCTTATCTGACGCGTCCGGGACAGGTCCGGTATAAAC
TTGTCTCCGGTCGTTCCCGCGGATACGGGCATGAGACCGAAGGGCCTGTATTTGCGACCGGAGAGGCGTCCTGGGGGCTC
AGTAACCAGTGGTCGCTGTATGGCGGGGCTGTGCTTGCCGGTGATTATAATGCACTGGCAGCCGGTGCCGGCTGGGACCT
GGGTGTGCCGGGGACCCTTTCCGCTGATATCACGCAGTCAGTAGCCCGTATTGAGGGAGAGAGAACGTTTCAGGGAAAAT
CCTGGCGTCTTAGCTACTCCAAACGGTTTGATAATGCGGATGCCGACATTACGTTCGCCGGGTATCGTTTCTCAGAGCGA
AACTATATGACCATGGAGCAGTACCTGAACGCCCGCTACCGTAATGATTACAGCAGTCGGGAAAAAGAGATGTATACCGT
TACGCTGAATAAAAACGTGGCGGACTGGAACACCTCTTTTAACCTGCAGTACAGCCGTCAGACATACTGGGACATACGGA
AAACGGACTATTATACGGTGAGCGTCAACCGCTACTTTAATGTTTTCGGACTGCAGGGAGTGGCGGTTGGATTGTCAGCC
TCAAGGTCTAAATATCTGGGGCGTGATAACGATTCTGCTTACCTGCGTATATCCGTGCCGCTGGGAACGGGGACAGCGAG
CTACAGTGGCAGTATGAGTAATGACCGTTATGTGAATATGGCCGGCTACACTGACACGTTCAATGACGGTCTGGACAGCT
ACAGCCTGAACGCCGGCCTTAACAGTGGCGGTGGACTGACATCGCAACGTCAGATTAATGCCTATTACAGTCATCGTAGT
CCGCTGGCAAATTTGTCCGCGAATATTGCATCCCTGCAGAAAGGATATACGTCTTTCGGCGTCAGTGCTTCCGGTGGGGC
AACAATTACCGGAAAAGGTGCGGCGTTACATGCAGGGGGAATGTCCGGTGGAACACGTCTTCTTGTTGACACGGATGGTG
TGGGAGGTGTACCGGTTGATGGCGGGCAGGTGGTGACAAATCGCTGGGGAACGGGCGTGGTGACTGACATCAGCAGTTAT
TACCGGAATACAACCTCTGTTGACCTGAAGCGCTTACCGGATGATGTGGAAGCAACCCGTTCTGTTGTGGAATCGGCGCT
GACAGAAGGTGCCATTGGTTACCGGAAATTCAGCGTGCTTAAAGGGAAACGTCTGTTTGCAATACTGCGTCTTGCTGATG
GCTCTCAGCCCCCGTTTGGTGCCAGTGTAACCAGTGAAAAAGGCCGGGAGCTGGGCATGGTGGCCGACGAAGGCCTTGCC
TGGCTGAGTGGCGTGACGCCGGGGGAAACCCTGTCGGTAAACTGGGATGGAAAAATACAGTGTCAGGTAAATGTACCGGA
GACAGCAATATCTGACCAGCAGTTATTGCTTCCCTGTACGCCTCAGAAATAA

Upstream 100 bases:

>100_bases
GGAAAAAAACTTGAAGCCGGAAATTATTTTGCCGTGCTGGGATTCCGGGTCGATTATGAGTGAGTCACTCCGGTGAGATG
TCCGGTTATTTATCTTTTTT

Downstream 100 bases:

>100_bases
ATGAAAGTCCGGAATATTAACGGCTGATGAATACGGTTATGCCATTTTCCGGACCAGGTGAAATTACAGAATGTGGAAAT
TAAGTATGATTCGAAAAAAG

Product: outer membrane usher protein PapC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 843; Mature: 843

Protein sequence:

>843_residues
MNLVMRGMKDRIPFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGYVLPGQYLLDVIVNGQSISPA
SLQISFVEPQSSGDKAEKKLPQACLTSDMVRLMGLTAESLDKVVYWHDGQCADFHGLPGVDIRPDTGAGVLRINMPQAWL
EYSDATWLPPSRWDDGIPGLMLDYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNF
TWSRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITGIAETNARVVVSQQGRVLYDS
MVPAGPFSIQDLDSSVRGRLDVEVIEQNGRKKTFQVDTASVPYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGL
SNQWSLYGGAVLAGDYNALAAGAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSER
NYMTMEQYLNARYRNDYSSREKEMYTVTLNKNVADWNTSFNLQYSRQTYWDIRKTDYYTVSVNRYFNVFGLQGVAVGLSA
SRSKYLGRDNDSAYLRISVPLGTGTASYSGSMSNDRYVNMAGYTDTFNDGLDSYSLNAGLNSGGGLTSQRQINAYYSHRS
PLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGGTRLLVDTDGVGGVPVDGGQVVTNRWGTGVVTDISSY
YRNTTSVDLKRLPDDVEATRSVVESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLA
WLSGVTPGETLSVNWDGKIQCQVNVPETAISDQQLLLPCTPQK

Sequences:

>Translated_843_residues
MNLVMRGMKDRIPFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGYVLPGQYLLDVIVNGQSISPA
SLQISFVEPQSSGDKAEKKLPQACLTSDMVRLMGLTAESLDKVVYWHDGQCADFHGLPGVDIRPDTGAGVLRINMPQAWL
EYSDATWLPPSRWDDGIPGLMLDYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNF
TWSRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITGIAETNARVVVSQQGRVLYDS
MVPAGPFSIQDLDSSVRGRLDVEVIEQNGRKKTFQVDTASVPYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGL
SNQWSLYGGAVLAGDYNALAAGAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSER
NYMTMEQYLNARYRNDYSSREKEMYTVTLNKNVADWNTSFNLQYSRQTYWDIRKTDYYTVSVNRYFNVFGLQGVAVGLSA
SRSKYLGRDNDSAYLRISVPLGTGTASYSGSMSNDRYVNMAGYTDTFNDGLDSYSLNAGLNSGGGLTSQRQINAYYSHRS
PLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGGTRLLVDTDGVGGVPVDGGQVVTNRWGTGVVTDISSY
YRNTTSVDLKRLPDDVEATRSVVESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLA
WLSGVTPGETLSVNWDGKIQCQVNVPETAISDQQLLLPCTPQK
>Mature_843_residues
MNLVMRGMKDRIPFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGYVLPGQYLLDVIVNGQSISPA
SLQISFVEPQSSGDKAEKKLPQACLTSDMVRLMGLTAESLDKVVYWHDGQCADFHGLPGVDIRPDTGAGVLRINMPQAWL
EYSDATWLPPSRWDDGIPGLMLDYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNF
TWSRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITGIAETNARVVVSQQGRVLYDS
MVPAGPFSIQDLDSSVRGRLDVEVIEQNGRKKTFQVDTASVPYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGL
SNQWSLYGGAVLAGDYNALAAGAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSER
NYMTMEQYLNARYRNDYSSREKEMYTVTLNKNVADWNTSFNLQYSRQTYWDIRKTDYYTVSVNRYFNVFGLQGVAVGLSA
SRSKYLGRDNDSAYLRISVPLGTGTASYSGSMSNDRYVNMAGYTDTFNDGLDSYSLNAGLNSGGGLTSQRQINAYYSHRS
PLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGGTRLLVDTDGVGGVPVDGGQVVTNRWGTGVVTDISSY
YRNTTSVDLKRLPDDVEATRSVVESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLA
WLSGVTPGETLSVNWDGKIQCQVNVPETAISDQQLLLPCTPQK

Specific function: Involved in the export and assembly of pili subunits across the outer membrane. Forms a hexameric ring-shaped pore in the outer bacterial membrane. The 2 nanometer-diameter pore allows the passage of the thin tip fibrillum. As for the rod, it probably unw

COG id: COG3188

COG function: function code NU; P pilus assembly protein, porin PapC

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial export usher family [H]

Homologues:

Organism=Escherichia coli, GI87081778, Length=830, Percent_Identity=36.7469879518072, Blast_Score=499, Evalue=1e-142,
Organism=Escherichia coli, GI1789533, Length=825, Percent_Identity=30.9090909090909, Blast_Score=304, Evalue=2e-83,
Organism=Escherichia coli, GI1786332, Length=847, Percent_Identity=29.5159386068477, Blast_Score=303, Evalue=3e-83,
Organism=Escherichia coli, GI1790772, Length=849, Percent_Identity=30.7420494699647, Blast_Score=285, Evalue=8e-78,
Organism=Escherichia coli, GI1786744, Length=846, Percent_Identity=27.8959810874704, Blast_Score=256, Evalue=4e-69,
Organism=Escherichia coli, GI1787172, Length=872, Percent_Identity=27.5229357798165, Blast_Score=255, Evalue=1e-68,
Organism=Escherichia coli, GI1788427, Length=801, Percent_Identity=26.8414481897628, Blast_Score=218, Evalue=1e-57,
Organism=Escherichia coli, GI1789610, Length=840, Percent_Identity=24.7619047619048, Blast_Score=131, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000015
- InterPro:   IPR018030 [H]

Pfam domain/function: PF00577 Usher [H]

EC number: NA

Molecular weight: Translated: 92343; Mature: 92343

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00059 ADH_ZINC ; PS01151 FIMBRIAL_USHER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLVMRGMKDRIPFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGY
CCCHHCCHHHCCCEEECCHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCEEEECCCCC
VLPGQYLLDVIVNGQSISPASLQISFVEPQSSGDKAEKKLPQACLTSDMVRLMGLTAESL
CCCHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
DKVVYWHDGQCADFHGLPGVDIRPDTGAGVLRINMPQAWLEYSDATWLPPSRWDDGIPGL
CCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCCCCCCCCCCCCCCCCE
MLDYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNF
EEEECCCCEEECCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCC
TWSRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITG
CHHEEEEEHHCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCEEE
IAETNARVVVSQQGRVLYDSMVPAGPFSIQDLDSSVRGRLDVEVIEQNGRKKTFQVDTAS
EECCCCEEEEECCCCEEEECCCCCCCCCHHHHCHHHCCCEEEEEEECCCCEEEEEEECCC
VPYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGLSNQWSLYGGAVLAGDYNALA
CCEEECCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCEEEECCCCEEE
AGAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSER
ECCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCEEEEHHHCCCCCCCCEEEEEEEECCC
NYMTMEQYLNARYRNDYSSREKEMYTVTLNKNVADWNTSFNLQYSRQTYWDIRKTDYYTV
CCEEHHHHHHHHHCCCCCCCCCEEEEEEEECCEECCCCEEEEEECCCEEEEEECCEEEEE
SVNRYFNVFGLQGVAVGLSASRSKYLGRDNDSAYLRISVPLGTGTASYSGSMSNDRYVNM
EEEEEEEEEECCEEEEECCCCCHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEE
AGYTDTFNDGLDSYSLNAGLNSGGGLTSQRQINAYYSHRSPLANLSANIASLQKGYTSFG
CCCCCCCCCCCCCEEECCCCCCCCCCCCCHHEEEEHHCCCCHHHHHHHHHHHHCCHHHCC
VSASGGATITGKGAALHAGGMSGGTRLLVDTDGVGGVPVDGGQVVTNRWGTGVVTDISSY
CCCCCCEEEECCCCEEECCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCEEHHHHHH
YRNTTSVDLKRLPDDVEATRSVVESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFG
HCCCCCEEHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECCCCCCCCC
ASVTSEKGRELGMVADEGLAWLSGVTPGETLSVNWDGKIQCQVNVPETAISDQQLLLPCT
CCCCCCCCCEECEECCCCCHHHCCCCCCCEEEEECCCEEEEEEECCCHHCCCCEEEECCC
PQK
CCC
>Mature Secondary Structure
MNLVMRGMKDRIPFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGY
CCCHHCCHHHCCCEEECCHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCEEEECCCCC
VLPGQYLLDVIVNGQSISPASLQISFVEPQSSGDKAEKKLPQACLTSDMVRLMGLTAESL
CCCHHHEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
DKVVYWHDGQCADFHGLPGVDIRPDTGAGVLRINMPQAWLEYSDATWLPPSRWDDGIPGL
CCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHCCCCCCCCCCCCCCCCCCCE
MLDYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNF
EEEECCCCEEECCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCCC
TWSRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITG
CHHEEEEEHHCCCCEEEEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCEEE
IAETNARVVVSQQGRVLYDSMVPAGPFSIQDLDSSVRGRLDVEVIEQNGRKKTFQVDTAS
EECCCCEEEEECCCCEEEECCCCCCCCCHHHHCHHHCCCEEEEEEECCCCEEEEEEECCC
VPYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGLSNQWSLYGGAVLAGDYNALA
CCEEECCCCEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCEEEECCCCEEE
AGAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSER
ECCCCCCCCCCCCCHHHHHHHHHHCCCEEECCCCEEEEHHHCCCCCCCCEEEEEEEECCC
NYMTMEQYLNARYRNDYSSREKEMYTVTLNKNVADWNTSFNLQYSRQTYWDIRKTDYYTV
CCEEHHHHHHHHHCCCCCCCCCEEEEEEEECCEECCCCEEEEEECCCEEEEEECCEEEEE
SVNRYFNVFGLQGVAVGLSASRSKYLGRDNDSAYLRISVPLGTGTASYSGSMSNDRYVNM
EEEEEEEEEECCEEEEECCCCCHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEE
AGYTDTFNDGLDSYSLNAGLNSGGGLTSQRQINAYYSHRSPLANLSANIASLQKGYTSFG
CCCCCCCCCCCCCEEECCCCCCCCCCCCCHHEEEEHHCCCCHHHHHHHHHHHHCCHHHCC
VSASGGATITGKGAALHAGGMSGGTRLLVDTDGVGGVPVDGGQVVTNRWGTGVVTDISSY
CCCCCCEEEECCCCEEECCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCEEHHHHHH
YRNTTSVDLKRLPDDVEATRSVVESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFG
HCCCCCEEHHHCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEEECCCCCCCCC
ASVTSEKGRELGMVADEGLAWLSGVTPGETLSVNWDGKIQCQVNVPETAISDQQLLLPCT
CCCCCCCCCEECEECCCCCHHHCCCCCCCEEEEECCCEEEEEEECCCHHCCCCEEEECCC
PQK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2897064; 1357526; 12399496; 2572580; 7909802; 9501230 [H]