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The map label for this gene is papH

Identifier: 218702823

GI number: 218702823

Start: 4786493

End: 4787080

Strand: Direct

Name: papH

Synonym: ECIAI39_4588

Alternate gene names: 218702823

Gene position: 4786493-4787080 (Clockwise)

Preceding gene: 218702822

Following gene: 218702824

Centisome position: 93.27

GC content: 49.32

Gene sequence:

>588_bases
ATGAGACTGCGATTCTCTGTTCCACTTTTCTTTTTTGGCTGTGTGTTTGTTCATGGTGTTTTTGCCGGTCCGTTTCCTCC
GCCCGGCATGTCCCTTCCTGAATACTGGGGAGAAGAACACGTATGGTGGGACGGCAGGGCTGCTTTTCATGGTGAGGTTG
TCAGACCTGCCTGTACTCTGGCGATGGAAGACGCCTGGCAGATTATCGATATGGGGGAAACCCCGGTTCGGGATTTACAG
AATGGTTTTTCCGGACCTGAAAGAAAATTCAGCCTCCGGCTCAGGAACTGTGAATTTAACAGTCAGGGTGGGAACCTTTT
CTCTGATTCCCGGATAAGGGTGACTTTCGATGGCGTCCGGGGTGAAACGCCGGATAAGTTTAATTTATCCGGTCAGGCAA
AAGGAATTAATCTGCAGATAGCTGATGCCAGGGGAAATATTGCCCGGGCAGGGAAAGTAATGCCTGCAATACCATTGACG
GGTAATGAAGAAGCGCTGGATTACACCCTCAGAATTGTGCGAAACGGAAAAAAACTTGAAGCCGGAAATTATTTTGCCGT
GCTGGGATTCCGGGTCGATTATGAGTGA

Upstream 100 bases:

>100_bases
CTCAGCAGTTGCGAATTTCAACCTGACTTATCAGTAATACTGATAATCCGGTCTGATAAACAGCGGATTTTTCCGCTGTT
TATTTCTCAGGGTATTTATC

Downstream 100 bases:

>100_bases
GTCACTCCGGTGAGATGTCCGGTTATTTATCTTTTTTGTGAATCTGGTGATGCGTGGAATGAAAGACAGAATACCTTTTG
CAGTCAACAATATTACCTGT

Product: minor pilin protein PapH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MRLRFSVPLFFFGCVFVHGVFAGPFPPPGMSLPEYWGEEHVWWDGRAAFHGEVVRPACTLAMEDAWQIIDMGETPVRDLQ
NGFSGPERKFSLRLRNCEFNSQGGNLFSDSRIRVTFDGVRGETPDKFNLSGQAKGINLQIADARGNIARAGKVMPAIPLT
GNEEALDYTLRIVRNGKKLEAGNYFAVLGFRVDYE

Sequences:

>Translated_195_residues
MRLRFSVPLFFFGCVFVHGVFAGPFPPPGMSLPEYWGEEHVWWDGRAAFHGEVVRPACTLAMEDAWQIIDMGETPVRDLQ
NGFSGPERKFSLRLRNCEFNSQGGNLFSDSRIRVTFDGVRGETPDKFNLSGQAKGINLQIADARGNIARAGKVMPAIPLT
GNEEALDYTLRIVRNGKKLEAGNYFAVLGFRVDYE
>Mature_195_residues
MRLRFSVPLFFFGCVFVHGVFAGPFPPPGMSLPEYWGEEHVWWDGRAAFHGEVVRPACTLAMEDAWQIIDMGETPVRDLQ
NGFSGPERKFSLRLRNCEFNSQGGNLFSDSRIRVTFDGVRGETPDKFNLSGQAKGINLQIADARGNIARAGKVMPAIPLT
GNEEALDYTLRIVRNGKKLEAGNYFAVLGFRVDYE

Specific function: PapH seems to anchor the pilus to the bacterial cell. In addition the stoichiometric relationship between papH and papA determines the pilus length [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted. Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 21807; Mature: 21807

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLRFSVPLFFFGCVFVHGVFAGPFPPPGMSLPEYWGEEHVWWDGRAAFHGEVVRPACTL
CEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEECCCEEECCCCCCHHHHE
AMEDAWQIIDMGETPVRDLQNGFSGPERKFSLRLRNCEFNSQGGNLFSDSRIRVTFDGVR
EHHCCEEEEECCCCCHHHHHHCCCCCCEEEEEEEECCEECCCCCCEECCCEEEEEECCCC
GETPDKFNLSGQAKGINLQIADARGNIARAGKVMPAIPLTGNEEALDYTLRIVRNGKKLE
CCCCCCCCCCCCCCCEEEEEECCCCCEECCCCCCEECCCCCCCHHHHEEEEEEECCCEEE
AGNYFAVLGFRVDYE
CCCEEEEEEEEEECC
>Mature Secondary Structure
MRLRFSVPLFFFGCVFVHGVFAGPFPPPGMSLPEYWGEEHVWWDGRAAFHGEVVRPACTL
CEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCEEECCCEEECCCCCCHHHHE
AMEDAWQIIDMGETPVRDLQNGFSGPERKFSLRLRNCEFNSQGGNLFSDSRIRVTFDGVR
EHHCCEEEEECCCCCHHHHHHCCCCCCEEEEEEEECCEECCCCCCEECCCEEEEEECCCC
GETPDKFNLSGQAKGINLQIADARGNIARAGKVMPAIPLTGNEEALDYTLRIVRNGKKLE
CCCCCCCCCCCCCCCEEEEEECCCCCEECCCCCCEECCCCCCCHHHHEEEEEEECCCEEE
AGNYFAVLGFRVDYE
CCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2882856; 1357526; 2897064 [H]