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The map label for this gene is yicJ [H]

Identifier: 218702351

GI number: 218702351

Start: 4266766

End: 4268166

Strand: Direct

Name: yicJ [H]

Synonym: ECIAI39_4097

Alternate gene names: 218702351

Gene position: 4266766-4268166 (Clockwise)

Preceding gene: 218702349

Following gene: 218702353

Centisome position: 83.14

GC content: 54.46

Gene sequence:

>1401_bases
ATGACCTCTACACCGATTACTACCGCTGATATCGCTAAAGGTAAAATTGACGATGCGTTATCTGTACGGGAAAAAATAGG
CTACGGCCTGGGTGACGCAGGCGGCACCGTAATAACTTGCCTGATCATGAACTTTCTCACCTTTTTCTACACCGACGTTT
TTGGCTTAACTCCGGCGCTGGTCGGCACGCTGTTTATTGCACTGCGCGTGTTTGATGCCATCTCCGACCCGGTGATGGGC
GTCATTGCCGACCGGACGCAAAGTCGCTGGGGGCGCTTTCGTCCGTGGCAGTTATGGATTGCCATTCCCATCGGCATTAT
CGGCATCCTGACGTTCACCGTGCCAGATGCCAGCATGGGAGTAAAAATCGCCTGGGCGTTCGGTACTTACCTGCTCCTTT
CAGTCGGTTATACCGCCATCAACGTACCGTACTGCGCGCTGATCAACACCATGACCACCCGCCACAATGAAGTGATCTCC
TGCCAGTCCTGGCGATTCGTTCTCTGCGGCGTAGCGGGATTTCTGGTTTCGGTAGGCTTACCGTGGATGGTAGATCTCTT
CGGGCAGGGTAATGCCGCGCGCGGCTATCAACTGGGCGTCGGCGTGCTGTGCGCCATCGCTGTGGTGATGTTCCTGTGCT
GTTTCTTCTGGGTTCGTGAACGGGTGCCACTCTCCACAATGGGGAAATTTACCCTGCGCGAACATCTTGCCGGGCTGCGA
AACAACGACCAACTACTGCTGATGCTGGTCATGTCTTTCCTGCTGATTAACGTCTTTAACATTCGCGGCGGTGGGTATAT
GTACTTCATTACCTACGTCTTACAAGGCAGTACGGGCTACACGTCGCTGTTCTTCACCATGGTCACCTTCGCCTCCATTA
TCGGCTCGGTGATTGTCAGCCCGTTAACGCGGCGTTTCGATACCGTCAAAATTTATTACTACACCAACCTGCTCCTCGCT
TCACTGGCGGTGTTGATGTGGTTCCTGCCCTCCGGCCCGGCTTATCAAACGCTGTGGCTGGCGGTGATCCTCGGTAATGG
CGTGATTCTTGGCTTCACATTGCCACTGCACTTCTCATTGATGGCCTTTGCCGATGACTACGGCGAGTGGAAAACCCGCG
TACGTTCTTCCGGCATGAACTTCGCCTTCAATCTGTTTTTCATCAAGCTGGCCTGGGCCTCCAGCGCCGGGATCATCAGC
CTGCTGTTTATTTTTGTCGCCTACCAGCCAGGCGTGGAAAACCAGACCGCCAGTTCGCTTGGCGGGATCGCGGCGATGGA
AACATTGCTGCCTGCGCTGTTCCACCTACTGCTGGCGATGGCGATCCGCTTTTGCAAACTCAATAACCCTATGATGTCAC
GCATTGCTAGCGACCTGCGTCAGCGTCATGTACAGCCTTAA

Upstream 100 bases:

>100_bases
TTTACTCTTTTCTCGCCTTGTTGATATTCCCGTTCACGGCAGAATTAATCATGTCATTGCAATAAAACTAAAAATTGCTC
CCTATTCACGAGGAATATCT

Downstream 100 bases:

>100_bases
GGAGCACAAGATGAACATTTCGGAAGTCGATCTGCATAAACTGACGGTCAGCGATCCGTTCCTCGGTCAGTACCAACAAC
TGGTCCGCGATGTGGTGATT

Product: putative permease of the major facilitator superfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTSTPITTADIAKGKIDDALSVREKIGYGLGDAGGTVITCLIMNFLTFFYTDVFGLTPALVGTLFIALRVFDAISDPVMG
VIADRTQSRWGRFRPWQLWIAIPIGIIGILTFTVPDASMGVKIAWAFGTYLLLSVGYTAINVPYCALINTMTTRHNEVIS
CQSWRFVLCGVAGFLVSVGLPWMVDLFGQGNAARGYQLGVGVLCAIAVVMFLCCFFWVRERVPLSTMGKFTLREHLAGLR
NNDQLLLMLVMSFLLINVFNIRGGGYMYFITYVLQGSTGYTSLFFTMVTFASIIGSVIVSPLTRRFDTVKIYYYTNLLLA
SLAVLMWFLPSGPAYQTLWLAVILGNGVILGFTLPLHFSLMAFADDYGEWKTRVRSSGMNFAFNLFFIKLAWASSAGIIS
LLFIFVAYQPGVENQTASSLGGIAAMETLLPALFHLLLAMAIRFCKLNNPMMSRIASDLRQRHVQP

Sequences:

>Translated_466_residues
MTSTPITTADIAKGKIDDALSVREKIGYGLGDAGGTVITCLIMNFLTFFYTDVFGLTPALVGTLFIALRVFDAISDPVMG
VIADRTQSRWGRFRPWQLWIAIPIGIIGILTFTVPDASMGVKIAWAFGTYLLLSVGYTAINVPYCALINTMTTRHNEVIS
CQSWRFVLCGVAGFLVSVGLPWMVDLFGQGNAARGYQLGVGVLCAIAVVMFLCCFFWVRERVPLSTMGKFTLREHLAGLR
NNDQLLLMLVMSFLLINVFNIRGGGYMYFITYVLQGSTGYTSLFFTMVTFASIIGSVIVSPLTRRFDTVKIYYYTNLLLA
SLAVLMWFLPSGPAYQTLWLAVILGNGVILGFTLPLHFSLMAFADDYGEWKTRVRSSGMNFAFNLFFIKLAWASSAGIIS
LLFIFVAYQPGVENQTASSLGGIAAMETLLPALFHLLLAMAIRFCKLNNPMMSRIASDLRQRHVQP
>Mature_465_residues
TSTPITTADIAKGKIDDALSVREKIGYGLGDAGGTVITCLIMNFLTFFYTDVFGLTPALVGTLFIALRVFDAISDPVMGV
IADRTQSRWGRFRPWQLWIAIPIGIIGILTFTVPDASMGVKIAWAFGTYLLLSVGYTAINVPYCALINTMTTRHNEVISC
QSWRFVLCGVAGFLVSVGLPWMVDLFGQGNAARGYQLGVGVLCAIAVVMFLCCFFWVRERVPLSTMGKFTLREHLAGLRN
NDQLLLMLVMSFLLINVFNIRGGGYMYFITYVLQGSTGYTSLFFTMVTFASIIGSVIVSPLTRRFDTVKIYYYTNLLLAS
LAVLMWFLPSGPAYQTLWLAVILGNGVILGFTLPLHFSLMAFADDYGEWKTRVRSSGMNFAFNLFFIKLAWASSAGIISL
LFIFVAYQPGVENQTASSLGGIAAMETLLPALFHLLLAMAIRFCKLNNPMMSRIASDLRQRHVQP

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI42713696, Length=428, Percent_Identity=25.2336448598131, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI211063479, Length=441, Percent_Identity=24.7165532879819, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082306, Length=449, Percent_Identity=37.6391982182628, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI1786466, Length=452, Percent_Identity=32.0796460176991, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1790561, Length=460, Percent_Identity=30, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI48994989, Length=450, Percent_Identity=24, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787902, Length=464, Percent_Identity=28.0172413793103, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI145693206, Length=466, Percent_Identity=25.1072961373391, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 51484; Mature: 51352

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TSTPITTADIAKGKIDDALSVREKIGYGLGDAGGTVITCLIMNFLTFFYTDVFGLTPAL
CCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]