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The map label for this gene is ygiE

Identifier: 218701813

GI number: 218701813

Start: 3688195

End: 3688968

Strand: Direct

Name: ygiE

Synonym: ECIAI39_3536

Alternate gene names: 218701813

Gene position: 3688195-3688968 (Clockwise)

Preceding gene: 218701811

Following gene: 218701816

Centisome position: 71.87

GC content: 52.58

Gene sequence:

>774_bases
ATGTCAGTACCTCTCATTCTGACCATACTGGCGGGGGCAGCCACGTTTATTGGCGCGTTTCTCGGCGTTCTCGGGCAAAA
ACCCTCGAACCGCTTACTGGCGTTTTCGCTAGGATTTGCGGCGGGGATCATGTTGCTCATCTCATTAATGGAAATGCTTC
CTGCCGCACTAGCAGCTGAAGGAATGTCGCCTGTGTTGGGTTATGGAATGTTTATCTTCGGTCTGCTTGGCTATTTTGGC
CTGGACCGCATGTTGCCACATGCGCATCCGCAGGATTTAATGCAAAAATCGGTGCAGCCGTTGCCAAAATCGATCAAGCG
CACAGCCATTCTGCTCACTCTCGGCATCAGTCTGCATAACTTCCCGGAAGGGATTGCCACCTTTGTCACGGCGAGCAGCA
ACCTGGAGCTGGGATTTGGCATCGCACTGGCCGTCGCGTTGCACAATATTCCTGAAGGTCTGGCGGTTGCAGGCCCGGTT
TATGCAGCAACGGGTTCTAAACGCACGGCAATTCTGTGGGCGGGGATTTCTGGATTGGCAGAAATTCTTGGTGGTGTGCT
GGCGTGGTTAATCCTCGGTAGCATGATTTCCCCGGTGGTCATGGCGGCAATCATGGCGGTGGTTGCAGGAATTATGGTGG
CGCTCTCGGTTGATGAATTAATGCCGCTCGCCAAAGAGATTGACCCTAATAATAACCCCAGCTATGGCGTACTATGTGGA
ATGTCAGTGATGGGATTCAGTTTAGTGCTGCTACAAACGGCGGGAATTGGTTAA

Upstream 100 bases:

>100_bases
ATACGCTTGTTCGGCGGAGTAAGAACCCGGATAACAATGATGATGATCATCAGTTATTTTGACGATCTGCCTGAAGGTGA
AGATTTATAAGGAGTTGTCG

Downstream 100 bases:

>100_bases
AAACAACATCAGAAGTTGTCCAGCACATGGACAACTTCTGCCAGCTTCACGAAAGCCTTATTCTACCTTTTCGGCTGTCT
CTTCTCTCGTACTGTTTAAG

Product: zinc transporter ZupT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFG
LDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAVVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCG
MSVMGFSLVLLQTAGIG

Sequences:

>Translated_257_residues
MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFG
LDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAVVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCG
MSVMGFSLVLLQTAGIG
>Mature_256_residues
SVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGL
DRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVY
AATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAVVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGM
SVMGFSLVLLQTAGIG

Specific function: Mediates zinc uptake. May also transport other divalent cations [H]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily [H]

Homologues:

Organism=Homo sapiens, GI229577422, Length=153, Percent_Identity=32.0261437908497, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI229577418, Length=153, Percent_Identity=32.0261437908497, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789419, Length=257, Percent_Identity=99.6108949416342, Blast_Score=496, Evalue=1e-142,
Organism=Caenorhabditis elegans, GI17507805, Length=174, Percent_Identity=31.0344827586207, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24652846, Length=183, Percent_Identity=25.6830601092896, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 26513; Mature: 26382

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
GMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHCCCHHCCCCCCCEEEEECCHHHHH
EILGGVLAWLILGSMISPVVMAAIMAVVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
MSVMGFSLVLLQTAGIG
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAE
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHC
GMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLA
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHCCCHHCCCCCCCEEEEECCHHHHH
EILGGVLAWLILGSMISPVVMAAIMAVVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
MSVMGFSLVLLQTAGIG
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA