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The map label for this gene is kpsE

Identifier: 218701715

GI number: 218701715

Start: 3584271

End: 3585419

Strand: Direct

Name: kpsE

Synonym: ECIAI39_3434

Alternate gene names: 218701715

Gene position: 3584271-3585419 (Clockwise)

Preceding gene: 218701714

Following gene: 218701716

Centisome position: 69.84

GC content: 49.87

Gene sequence:

>1149_bases
ATGTTGATAAAAGTGAAGTCTGCCGTATCCTGGATGCGTGCTCGTCTGTCTGCCATCTCACTGGCAGATATCCAAAAACA
CCTGGCGAAAATCATCATTCTGGCACCGATGGCGGTGCTGCTGATCTATCTGGCTATCTTCAGCCAGCCTCGTTATATGA
GCGAGTCGAAAGTCGCCATTAAACGCTCGGATGATTTAAACAGCGGCAGCCTGAATTTTGGTCTGCTTCTGGGTGCCTCT
AACCCCAGTTCCGCAGAAGATGCGTTGTATCTGAAAGAGTACATCAACTCGCCGGATATGCTGGCGGCGCTGGATAAGCA
ACTAAATTTTCGTGAAGCGTTTAGCCACAGCGGGCTCGATTTTCTTAATCATCTTAGCAAGGATGAAACCGCAGAAGGCT
TCCTGAAGTACTACAAGGACCGTATCAACGTCTCGTATGACGATAAAACCGGATTACTGAATATTCAGACGCAGGGCTTT
AGCCCGGAGTTTTCGCTTAAGTTTAACCAGACCGTGCTGAAAGAGTCAGAGCGCTTTATCAATGAGATGTCACATCGCAT
CGCGCGTGACCAGCTTGCCTTTGCAGAAACGGAGATGGAAAAGGCACGCCAGCGTCTGGACGCCAGCAAAGCGGAATTGC
TCTCTTATCAGGACAACAACAACGTTCTGGATCCACAGGCACAGGCACAGGCGGCGAGCACGTTAGTGAATACGCTGATG
GGCCAGAAGATCCAGATGGAAGCGGACCTGCGGAACTTGCTGACGTATCTGCGTGAGGACGCCCCGCAAGTTGTGAGTGC
GCGTAATGCGATTCAGTCATTGCAGGCACAAATTGACGAAGAAAAAAGCAAAATCACAGCGCCGCAGGGTGACAAGCTAA
ACCGTATGGCGGTGGATTTTGAAGAAATCAAATCAAAAGTAGAGTTCAACACCGAGCTGTACAAACTGACCCTGACCTCC
ATTGAAAAGACCCGTGTAGAAGCGGCTCGTAAGCTCAAGGTGCTGTCAGTGATCAGTTCGCCACAGTTGCCGCAGGAATC
GTCTTTTCCAAATATCCCTTATTTGATCGCCTGCTGGTTACTGGTGTGCTGCCTGCTGTTCGGCACCCTGAAACTGTTGC
TGGCTGTTATTGAAGATCACCGAGACTAA

Upstream 100 bases:

>100_bases
TCACTGGCCTTGTGCGCATTTTCGACTAATTAAGCAACGGGGTGCGAGAGGTTAGTCTCTCATTGAGTTTGCGCCCCACT
GAAACTTTGATAATCGTTAC

Downstream 100 bases:

>100_bases
CGCTGTCGCTGAATGAGTTTGTGATGAAATTATTTAAATCAATTTTACTGATTGCCGCCTGTCACGCGGCGCAGGCCAGC
GCGGCCATTGATATTAACGC

Product: capsule polysaccharide export inner-membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MLIKVKSAVSWMRARLSAISLADIQKHLAKIIILAPMAVLLIYLAIFSQPRYMSESKVAIKRSDDLNSGSLNFGLLLGAS
NPSSAEDALYLKEYINSPDMLAALDKQLNFREAFSHSGLDFLNHLSKDETAEGFLKYYKDRINVSYDDKTGLLNIQTQGF
SPEFSLKFNQTVLKESERFINEMSHRIARDQLAFAETEMEKARQRLDASKAELLSYQDNNNVLDPQAQAQAASTLVNTLM
GQKIQMEADLRNLLTYLREDAPQVVSARNAIQSLQAQIDEEKSKITAPQGDKLNRMAVDFEEIKSKVEFNTELYKLTLTS
IEKTRVEAARKLKVLSVISSPQLPQESSFPNIPYLIACWLLVCCLLFGTLKLLLAVIEDHRD

Sequences:

>Translated_382_residues
MLIKVKSAVSWMRARLSAISLADIQKHLAKIIILAPMAVLLIYLAIFSQPRYMSESKVAIKRSDDLNSGSLNFGLLLGAS
NPSSAEDALYLKEYINSPDMLAALDKQLNFREAFSHSGLDFLNHLSKDETAEGFLKYYKDRINVSYDDKTGLLNIQTQGF
SPEFSLKFNQTVLKESERFINEMSHRIARDQLAFAETEMEKARQRLDASKAELLSYQDNNNVLDPQAQAQAASTLVNTLM
GQKIQMEADLRNLLTYLREDAPQVVSARNAIQSLQAQIDEEKSKITAPQGDKLNRMAVDFEEIKSKVEFNTELYKLTLTS
IEKTRVEAARKLKVLSVISSPQLPQESSFPNIPYLIACWLLVCCLLFGTLKLLLAVIEDHRD
>Mature_382_residues
MLIKVKSAVSWMRARLSAISLADIQKHLAKIIILAPMAVLLIYLAIFSQPRYMSESKVAIKRSDDLNSGSLNFGLLLGAS
NPSSAEDALYLKEYINSPDMLAALDKQLNFREAFSHSGLDFLNHLSKDETAEGFLKYYKDRINVSYDDKTGLLNIQTQGF
SPEFSLKFNQTVLKESERFINEMSHRIARDQLAFAETEMEKARQRLDASKAELLSYQDNNNVLDPQAQAQAASTLVNTLM
GQKIQMEADLRNLLTYLREDAPQVVSARNAIQSLQAQIDEEKSKITAPQGDKLNRMAVDFEEIKSKVEFNTELYKLTLTS
IEKTRVEAARKLKVLSVISSPQLPQESSFPNIPYLIACWLLVCCLLFGTLKLLLAVIEDHRD

Specific function: Involved in the translocation of the polysialic acid capsule [H]

COG id: COG3524

COG function: function code M; Capsule polysaccharide export protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexC/CtrB/KpsE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005705 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 43061; Mature: 43061

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIKVKSAVSWMRARLSAISLADIQKHLAKIIILAPMAVLLIYLAIFSQPRYMSESKVAI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
KRSDDLNSGSLNFGLLLGASNPSSAEDALYLKEYINSPDMLAALDKQLNFREAFSHSGLD
EECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCHH
FLNHLSKDETAEGFLKYYKDRINVSYDDKTGLLNIQTQGFSPEFSLKFNQTVLKESERFI
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHH
NEMSHRIARDQLAFAETEMEKARQRLDASKAELLSYQDNNNVLDPQAQAQAASTLVNTLM
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
GQKIQMEADLRNLLTYLREDAPQVVSARNAIQSLQAQIDEEKSKITAPQGDKLNRMAVDF
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCH
EEIKSKVEFNTELYKLTLTSIEKTRVEAARKLKVLSVISSPQLPQESSFPNIPYLIACWL
HHHHHHHHHCHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LVCCLLFGTLKLLLAVIEDHRD
HHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIKVKSAVSWMRARLSAISLADIQKHLAKIIILAPMAVLLIYLAIFSQPRYMSESKVAI
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
KRSDDLNSGSLNFGLLLGASNPSSAEDALYLKEYINSPDMLAALDKQLNFREAFSHSGLD
EECCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCHH
FLNHLSKDETAEGFLKYYKDRINVSYDDKTGLLNIQTQGFSPEFSLKFNQTVLKESERFI
HHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEHHHHHHHHHHHHH
NEMSHRIARDQLAFAETEMEKARQRLDASKAELLSYQDNNNVLDPQAQAQAASTLVNTLM
HHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
GQKIQMEADLRNLLTYLREDAPQVVSARNAIQSLQAQIDEEKSKITAPQGDKLNRMAVDF
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCH
EEIKSKVEFNTELYKLTLTSIEKTRVEAARKLKVLSVISSPQLPQESSFPNIPYLIACWL
HHHHHHHHHCHHHHEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LVCCLLFGTLKLLLAVIEDHRD
HHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8253690 [H]