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The map label for this gene is hdfR

Identifier: 218701322

GI number: 218701322

Start: 3133099

End: 3133938

Strand: Direct

Name: hdfR

Synonym: ECIAI39_3021

Alternate gene names: 218701322

Gene position: 3133099-3133938 (Clockwise)

Preceding gene: 218701320

Following gene: 218701325

Centisome position: 61.05

GC content: 48.1

Gene sequence:

>840_bases
GTGGATACGGAATTGTTAAAAACTTTCCTGGAAGTTAGCCGAACGCGTCACTTTGGTCGAGCGGCTGAATCGCTCTATCT
GACCCAATCAGCCGTGAGCTTTCGAATCAGACAACTGGAAAATCAACTGGGTGTGAATCTTTTCACCCGCCACAGAAACA
ATATCCGTTTAACCGCTGCCGGTGAAAAACTACTGCCTTATGCAGAAACGCTCATGAGCACCTGGCAGGCCGCCCGTAAG
GAGGTGGCGCATACCTCACGACATAACGAGTTTTCTATCGGTGCCAGCGCCTCATTGTGGGAATGTATGCTTAATCAGTG
GCTGGGACGTTTGTATAAAAATCAGGATGCCCATACAGGCTTACAGTTCGAAGCGCGAATTGCCCAACGACAGTCTCTGG
TAAAACAGCTGCATGAACGCCAGCTTGATCTTCTTATTACTACTGAAGCGCCCAAAATGGACGAATTTAGCAGTCAGTTG
CTCGGGTATTTCACTTTAGCGCTTTATACCAGTGCCCCTTCTAAACTAAAGGGAGATCTTAACTATCTGCGACTGGAGTG
GGGGCCAGATTTTCAACAGCATGAGGCAGGTTTGATCGGTGCTGACGAAGTTCCCATTCTGACAACCAGTTCTGCTGAAC
TGGCACAGCAACAGATTGCGATGCTTAATGGTTGCACCTGGCTACCCGTCAGTTGGGCGCGTAAAAAGGGCGGCCTGCAT
ACCGTTGTCGATAGCACAACACTTTCACGGCCGCTTTATGCCATATGGCTGCAAAATAGCGATAAAAATGCGTTGATTCG
CGATCTATTGAAAATTAACGTGCTGGATGAAGTGTATTAA

Upstream 100 bases:

>100_bases
TTTGACCGAGCTAGTTATGGCGCGGAGTATTAGTTACGCTTGACAGAGTGTAAAACAAAACATTTAAATCATAACGACAA
ATAATTTTGCGGAGAGCACT

Downstream 100 bases:

>100_bases
TCTGAATGGCTGGCAAGGATGCCGGTAGAAGGATTTACTTCGGAGAGGTTATTTCAGATAAAAAAAATCCTTAGCTTTCG
CTAAGGATGATTTCTGGCAG

Product: transcriptional regulator HdfR

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARK
EVAHTSRHNEFSIGASASLWECMLNQWLGRLYKNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY

Sequences:

>Translated_279_residues
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARK
EVAHTSRHNEFSIGASASLWECMLNQWLGRLYKNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
>Mature_279_residues
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARK
EVAHTSRHNEFSIGASASLWECMLNQWLGRLYKNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=279, Percent_Identity=99.6415770609319, Blast_Score=573, Evalue=1e-165,
Organism=Escherichia coli, GI1788626, Length=151, Percent_Identity=30.4635761589404, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI2367136, Length=254, Percent_Identity=26.7716535433071, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=68, Percent_Identity=44.1176470588235, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31747; Mature: 31747

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
GEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYKNQDAHTG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
LQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGYFTLALYTSAPSKLKGDL
CHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCC
NYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
EEEEEECCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCHHHHHCCCEE
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
EEECCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEEC
GEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWECMLNQWLGRLYKNQDAHTG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
LQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGYFTLALYTSAPSKLKGDL
CHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHCCCC
NYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
EEEEEECCCCHHHHCCCCCCCCCCCEEECCHHHHHHHHHHHHCCCCCCCCHHHHHCCCEE
TVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLDEVY
EEECCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA