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The map label for this gene is norR

Identifier: 218701199

GI number: 218701199

Start: 3001227

End: 3002741

Strand: Reverse

Name: norR

Synonym: ECIAI39_2895

Alternate gene names: 218701199

Gene position: 3002741-3001227 (Counterclockwise)

Preceding gene: 218701202

Following gene: 218701191

Centisome position: 58.51

GC content: 57.1

Gene sequence:

>1515_bases
ATGAGTTTTTCCGTTGATATGCTGGCGAATATCGCCATCGAATTGCAGCGTGGGATTGGTCATCAGGATCGTTTTCAGCG
CCTGATCACCACGCTGCGTCAGGTGCTGGAGTGCGATGCGTCTGCATTGCTACGTTACGACTCGCGGCAGTTTATTCCGC
TTGCCATCGACGGACTGGCAAAGGATGTACTCGGTAGACGCTTTGCGCTGGAAGGGCATCCACGGCTGGAAGCGATTGCC
CGCGCCGGGGACGTGGTGCGCTTTCCCGCAGACAGCGAATTGCCCGATCCCTATGACGGTTTGATTCCCGGGCAGGAGAG
TCTGAAGGTTCACGCCTGCGTTGGTCTGCCATTGTTTGCCGGGCAAAACCTGATCGGCGCATTGACGCTCGACGGGATGC
AGCCCGATCAGTTCGATGTTTTCAGCGACGAAGAGTTACGCCTGATTGCCGCGCTGGCGGCGGGAGCGTTAAGCAATGCG
TTGCTGATTGAACAACTGGAAAGTCAGAATATGCTGCCGGGCGATGCCGCGCCGTTTGAAGCGCTGAAAGAGACGCAGAT
GATCGGCCTGTCGCCAGGCATGACGCAATTGAAAAAAGAGATTGAGATTGTGGCGGCGTCCGATCTCAACGTCCTGATTA
GCGGTGAGACGGGAACCGGTAAGGAGCTGGTGGCGAAAGCGATTCATGAAGCCTCGCCAAGGGCGGTGAATCCGTTGGTC
TATCTCAACTGTGCCGCACTGCCGGAAAGTGTGGCGGAAAGTGAGTTGTTCGGGCACGTGAAAGGGGCGTTTACTGGCGC
TATCAGTAACCGCAGCGGGAAGTTTGAAATGGCGGATAACGGCACGCTGTTTCTCGATGAGATCGGCGAGTTGTCGTTGG
CATTGCAGGCCAAGCTGCTGAGGGTGTTGCAGTATGGCGATATTCAGCGCGTTGGCGATGACCGCAGTTTGCGGGTCGAT
GTGCGCGTGCTGGCGGCGACTAACCGCGACTTACGCGAAGAGGTGCTGGCAGGGCGATTCCGCGCCGATTTGTTTCATCG
CCTGAGCGTGTTTCCACTTTCGGTGCCGCCGCTGCGTGAGCGGGGCGATGATGTCATTCTGCTGGCGGGGTATTTCTGCG
AACAGTGCCGCCTGCGGTTGGGGCTTTCCCGCGTGGTGTTAAGTTCCGGGGCGCGGAATTTATTGCAACATTATAGTTTC
CCGGGGAACGTTCGTGAACTGGAACATGCTATTCATCGGGCGGTAGTGCTGGCGAGAGCAACCCGCAGCGGCGATGAAGT
GATTCTTGAAGCGCAACATTTTGCTTTTCCTGAGGTGACGTTGCCGCCGCCAGAAGCGGCGGCGGTGCCTATCGTTAAGC
AAAATCTGCGTGAAGCGACAGAAGCGTTCCAGCGTGAAACCATTCGTCAGGCACAGGCACAAAATCATCACAACTGGGCT
GCCAGCGCACGGATGCTGGAAACCGACGTCGCCAACTTGCATCGGTTGGCGAAACGTCTGGGGCTGAAGGATTAA

Upstream 100 bases:

>100_bases
TGTATAAATTAATTCATGCTCATTAATGAGTAGTCAAAATGACTATTAATAAAATGGTCGATATGACAATATCTATAGTC
AAATTGACAGTGAGGCAAAG

Downstream 100 bases:

>100_bases
ATAATCCCGGCCTGATAGAAATCCTGCAGGTTAATTGCGCCGGTGAGTTTGCCGTTTTCATCCACTACCGGTGCGGCGGT
GATTTTGCGTTTCATCAGGA

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MSFSVDMLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIA
RAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
LLIEQLESQNMLPGDAAPFEALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVD
VRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSSGARNLLQHYSF
PGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQAQAQNHHNWA
ASARMLETDVANLHRLAKRLGLKD

Sequences:

>Translated_504_residues
MSFSVDMLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIA
RAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
LLIEQLESQNMLPGDAAPFEALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVD
VRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSSGARNLLQHYSF
PGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQAQAQNHHNWA
ASARMLETDVANLHRLAKRLGLKD
>Mature_503_residues
SFSVDMLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIAR
AGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNAL
LIEQLESQNMLPGDAAPFEALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVY
LNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDV
RVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSSGARNLLQHYSFP
GNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQAQAQNHHNWAA
SARMLETDVANLHRLAKRLGLKD

Specific function: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54 [H]

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082152, Length=504, Percent_Identity=97.6190476190476, Blast_Score=957, Evalue=0.0,
Organism=Escherichia coli, GI1789087, Length=357, Percent_Identity=40.8963585434174, Blast_Score=261, Evalue=9e-71,
Organism=Escherichia coli, GI87082117, Length=316, Percent_Identity=47.4683544303797, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790437, Length=231, Percent_Identity=55.8441558441558, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1788550, Length=299, Percent_Identity=45.819397993311, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI1790299, Length=246, Percent_Identity=47.5609756097561, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI1788905, Length=254, Percent_Identity=45.2755905511811, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1789233, Length=333, Percent_Identity=39.039039039039, Blast_Score=211, Evalue=8e-56,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=38.9240506329114, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1787583, Length=338, Percent_Identity=36.9822485207101, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1786524, Length=246, Percent_Identity=45.5284552845528, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1789828, Length=247, Percent_Identity=36.4372469635627, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI87081858, Length=207, Percent_Identity=34.2995169082126, Blast_Score=108, Evalue=8e-25,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002078 [H]

Pfam domain/function: PF01590 GAF; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55220; Mature: 55089

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSVDMLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEHHHHHHH
KDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFA
HHHHCCEEECCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHC
GQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFE
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
HHHHHHHCCCCCCHHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEE
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLL
EEEEHHCCHHHHHHHHHHHHHHHHEEEECCCCCCEEECCCCEEEEEHHHHHHHHHHHHHH
RVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRE
HHHHCCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RGDDVILLAGYFCEQCRLRLGLSRVVLSSGARNLLQHYSFPGNVRELEHAIHRAVVLARA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQAQAQNHHNWA
CCCCCEEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ASARMLETDVANLHRLAKRLGLKD
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFSVDMLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLA
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEHHHHHHH
KDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFA
HHHHCCEEECCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHC
GQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFE
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
HHHHHHHCCCCCCHHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEE
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLL
EEEEHHCCHHHHHHHHHHHHHHHHEEEECCCCCCEEECCCCEEEEEHHHHHHHHHHHHHH
RVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRE
HHHHCCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RGDDVILLAGYFCEQCRLRLGLSRVVLSSGARNLLQHYSFPGNVRELEHAIHRAVVLARA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQAQAQNHHNWA
CCCCCEEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ASARMLETDVANLHRLAKRLGLKD
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA