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The map label for this gene is xapB

Identifier: 218700869

GI number: 218700869

Start: 2646013

End: 2647269

Strand: Reverse

Name: xapB

Synonym: ECIAI39_2548

Alternate gene names: 218700869

Gene position: 2647269-2646013 (Counterclockwise)

Preceding gene: 218700870

Following gene: 218700868

Centisome position: 51.58

GC content: 45.35

Gene sequence:

>1257_bases
ATGAATATCGCAACGCGTTTAAAGGTAATGTCTTTCTTACAATACTTTATCTGGGGGAGTTGGTTAGTTACCCTCGGCTC
TTACATGATAAACACCTTACATTTTACCGGGGCTGATGTCGGTATGGCATACAGTTCTAAAGGTATTGCGGCCATTATTA
TGCCAGCCGTTATGGGCATTATTGCCGATAAATGGTTACGGGCTGAACGTACCTATATGCTGTGTCACTTAATTTGTGCC
GGGGTGCTTTTTTATGCCGCCTCTGTAACTGAACCGAATATGATGTTCTGGGTGATGTTGCTTAACGCGATGGCTTTCAT
GCCCACGATTGCGTTATCCAACAGTGTTTCCTATTCGTGTTTGGCGCAGGCCGGATTAGATCCGGTCACCAGTTTTCCGC
CAATCCGTGTTTATGGTACCGTGGGATTTATTGTCGCAATGTGGCTGGTGAGTTTATTGCATCTGGAGTTAAGCAGTGTG
CAATTGTATATCGCCTCCGGAGCATCTCTAGTGCTAGCGGTCTATGCGTTAACGTTACCGAAAATTCCAGTGGCGGAACA
TAAGGCCAGTACGACGCTTTCCAGTAAATTAGGTCTGGATGCGTTTGTGTTATTTAAAAATCCACGTATGGCGATTTTCT
TTTTATTTGCCATGTTATTAGGGGCGGTCCTGCAAATTACTAACGTTTTTGGTAATCCTTTTCTGCATGATTTTGCCCGC
ACCCCTGAGTTTTCTGATAGCTTCGTGGTGAAATATCCTTCCATTCTGCTCTCGGTATCACAAATGGCGGAAGTCGGCTT
CATTCTGACTATTCCTTTCTTTCTGAAGCGTTTTGGCATCAAAACCGTCATGTTGATGAGTATGGTAGCGTGGACATTAC
GTTTTGGATTCTTTGCTTTTGGAGATCCGTCACCAGGTGGCTTTGTATTATTGCTGCTGTCGATGATTGTGTATGGCTGC
GCGTTCGACTTTTTCAATATTTCCGGTTCAGTGTTTGTCGAGCAAGAAGTGGACTCCAGGATCCGCGCCAGCGCCCAGGG
ATTATTTATGACCATGGTCAATGGCGTTGGGGCGTGGATTGGTTCTCTTCTGAGTGGCATGGCAGTTGACTATTTCACGG
TTGATGGTGTTAAAGACTGGCAAACCATCTGGCTGGTATTTGCTGCGTATGCACTGGCCTTAGCGGTGATTTTTGCCCTG
TTCTTCCGTTATAAACATGAACCTGAAAAAATGGCACAGAAATCATTGGCTCACTGA

Upstream 100 bases:

>100_bases
CTTTATTAATCTGATTTGCGGATTCTTACGCAAAATCGCCTGAAAACAATAAAAATGGCCTCGCGGATGGGGCCATCTCA
CTGCGATAAGGAAATAAAAA

Downstream 100 bases:

>100_bases
TGTAAACAGGGTTTTCCTTGATTGCAATGTGCTAAGTTTGCAGCCTTACCCATACCGTATGGAGCGCAATAATTATGGAA
AGTACACATCGTATTGATCT

Product: xanthosine transporter

Products: Proton [Cytoplasm]; xanthosine [Cytoplasm] [C]

Alternate protein names: Xanthosine transporter [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MNIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGADVGMAYSSKGIAAIIMPAVMGIIADKWLRAERTYMLCHLICA
GVLFYAASVTEPNMMFWVMLLNAMAFMPTIALSNSVSYSCLAQAGLDPVTSFPPIRVYGTVGFIVAMWLVSLLHLELSSV
QLYIASGASLVLAVYALTLPKIPVAEHKASTTLSSKLGLDAFVLFKNPRMAIFFLFAMLLGAVLQITNVFGNPFLHDFAR
TPEFSDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAFGDPSPGGFVLLLLSMIVYGC
AFDFFNISGSVFVEQEVDSRIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFTVDGVKDWQTIWLVFAAYALALAVIFAL
FFRYKHEPEKMAQKSLAH

Sequences:

>Translated_418_residues
MNIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGADVGMAYSSKGIAAIIMPAVMGIIADKWLRAERTYMLCHLICA
GVLFYAASVTEPNMMFWVMLLNAMAFMPTIALSNSVSYSCLAQAGLDPVTSFPPIRVYGTVGFIVAMWLVSLLHLELSSV
QLYIASGASLVLAVYALTLPKIPVAEHKASTTLSSKLGLDAFVLFKNPRMAIFFLFAMLLGAVLQITNVFGNPFLHDFAR
TPEFSDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAFGDPSPGGFVLLLLSMIVYGC
AFDFFNISGSVFVEQEVDSRIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFTVDGVKDWQTIWLVFAAYALALAVIFAL
FFRYKHEPEKMAQKSLAH
>Mature_418_residues
MNIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGADVGMAYSSKGIAAIIMPAVMGIIADKWLRAERTYMLCHLICA
GVLFYAASVTEPNMMFWVMLLNAMAFMPTIALSNSVSYSCLAQAGLDPVTSFPPIRVYGTVGFIVAMWLVSLLHLELSSV
QLYIASGASLVLAVYALTLPKIPVAEHKASTTLSSKLGLDAFVLFKNPRMAIFFLFAMLLGAVLQITNVFGNPFLHDFAR
TPEFSDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAFGDPSPGGFVLLLLSMIVYGC
AFDFFNISGSVFVEQEVDSRIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFTVDGVKDWQTIWLVFAAYALALAVIFAL
FFRYKHEPEKMAQKSLAH

Specific function: Nucleoside transport [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli nupG and yegT [H]

Homologues:

Organism=Escherichia coli, GI1788745, Length=418, Percent_Identity=88.5167464114833, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI87082192, Length=418, Percent_Identity=58.3732057416268, Blast_Score=497, Evalue=1e-142,
Organism=Escherichia coli, GI1788415, Length=428, Percent_Identity=28.9719626168224, Blast_Score=192, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR004740 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46166; Mature: 46166

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGADVGMAYSSKGIAAIIMPAVMGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
IADKWLRAERTYMLCHLICAGVLFYAASVTEPNMMFWVMLLNAMAFMPTIALSNSVSYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LAQAGLDPVTSFPPIRVYGTVGFIVAMWLVSLLHLELSSVQLYIASGASLVLAVYALTLP
HHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCC
KIPVAEHKASTTLSSKLGLDAFVLFKNPRMAIFFLFAMLLGAVLQITNVFGNPFLHDFAR
CCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
TPEFSDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAF
CCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
GDPSPGGFVLLLLSMIVYGCAFDFFNISGSVFVEQEVDSRIRASAQGLFMTMVNGVGAWI
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLLSGMAVDYFTVDGVKDWQTIWLVFAAYALALAVIFALFFRYKHEPEKMAQKSLAH
HHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure
MNIATRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGADVGMAYSSKGIAAIIMPAVMGI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHH
IADKWLRAERTYMLCHLICAGVLFYAASVTEPNMMFWVMLLNAMAFMPTIALSNSVSYSC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
LAQAGLDPVTSFPPIRVYGTVGFIVAMWLVSLLHLELSSVQLYIASGASLVLAVYALTLP
HHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHCC
KIPVAEHKASTTLSSKLGLDAFVLFKNPRMAIFFLFAMLLGAVLQITNVFGNPFLHDFAR
CCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHC
TPEFSDSFVVKYPSILLSVSQMAEVGFILTIPFFLKRFGIKTVMLMSMVAWTLRFGFFAF
CCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
GDPSPGGFVLLLLSMIVYGCAFDFFNISGSVFVEQEVDSRIRASAQGLFMTMVNGVGAWI
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLLSGMAVDYFTVDGVKDWQTIWLVFAAYALALAVIFALFFRYKHEPEKMAQKSLAH
HHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; xanthosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + xanthosine [Periplasm] = Proton [Cytoplasm] + xanthosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7559336; 9205837; 9278503 [H]