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The map label for this gene is marC

Identifier: 218700176

GI number: 218700176

Start: 1908348

End: 1909013

Strand: Reverse

Name: marC

Synonym: ECIAI39_1825

Alternate gene names: 218700176

Gene position: 1909013-1908348 (Counterclockwise)

Preceding gene: 218700180

Following gene: 218700169

Centisome position: 37.2

GC content: 50.0

Gene sequence:

>666_bases
ATGTTAGATTTGTTTAAAGCAATAGGCCTGGGGCTGGTGGTGTTACTACCGTTAGCTAACCCATTAACAACTGTCGCGTT
ATTTCTTGGCCTGGCAGGCAACATGAACAGTGCTGAACGTAATCGTCAGTCGTTGATGGCCTCGGTGTACGTATTTGCCA
TCATGATGGTGGCGTATTACGCCGGGCAACTGGTGATGGATACATTTGGCATTTCGATTCCCGGTCTGCGAATTGCAGGC
GGCTTAATCGTCGCGTTTATCGGTTTTCGGATGCTCTTTCCGCAACAGAAAGCGATTGATTCACCGGAAGCGAAAAGCAA
GTCGGAAGAGCTGGAAGATGAACCCAGCGCTAATATTGCTTTTGTACCACTGGCAATGCCAAGTACCGCCGGTCCGGGAA
CCATAGCGATGATTATTAGCTCGGCGTCCACAGTGCGTCAGAGTTCAACCTTTGCTGATTGGGTACTGATGGTTGCGCCG
CCGCTGATCTTTTTCCTGGTGGCGGTTATTTTGTGGGGAAGTCTACGCAGCTCTGGCGCAATTATGCGGCTGGTGGGTAA
GGGGGGCATTGAAGCGATCTCCCGTCTGATGGGATTCCTGCTGGTATGTATGGGGGTGCAGTTTATTATTAACGGCATCC
TGGAAATCATTAAAACGTACCACTAA

Upstream 100 bases:

>100_bases
GGTCAATGCGATGCAAGGTTAGCGAAAGAGTGACACTTTATCGTTGTTTACCCCTTATACTTTTCGCTGATAAACCAGAT
ACACAGGATAACAACCACCA

Downstream 100 bases:

>100_bases
AAAAGGCCCAAATGGGCCTTTCAACTATTGCGTCTGTTCTTCGAGTGTCACTGGCCAGCGGCGGAAAATGATGATTGACC
ATATTAACGCGGCAAAGGCA

Product: multiple drug resistance protein MarC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTYH

Sequences:

>Translated_221_residues
MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTYH
>Mature_221_residues
MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTYH

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787809, Length=221, Percent_Identity=100, Blast_Score=439, Evalue=1e-125,
Organism=Escherichia coli, GI1787494, Length=199, Percent_Identity=31.1557788944724, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1789842, Length=207, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 23618; Mature: 23618

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYY
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHCCCCCCCEE
FVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAPPLIFFLVAVILWGSLRSSGA
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTYH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQSLMASVYVFAIMMVAYY
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIA
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHCCCCCCCEE
FVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAPPLIFFLVAVILWGSLRSSGA
EEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
IMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTYH
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA