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The map label for this gene is baeS

Identifier: 218699329

GI number: 218699329

Start: 990796

End: 992199

Strand: Reverse

Name: baeS

Synonym: ECIAI39_0936

Alternate gene names: 218699329

Gene position: 992199-990796 (Counterclockwise)

Preceding gene: 218699330

Following gene: 218699328

Centisome position: 19.33

GC content: 54.2

Gene sequence:

>1404_bases
ATGAAGTTCTGGCGACCCGGTATTACCGGCAAACTGTTTCTGGCGATTTTCGCCACCTGCATTGTCTTGCTGATCAGTAT
GCACTGGGCGGTGCGTATCAGTTTTGAGCGTGGCTTTATTGATTACATCAAGCATGGTAATGAACAACGGCTGCAAATGC
TCGGCGATGCGCTTGGTGAGCAGTACGCCCAGCACGGGAACTGGCGCTTCCTGCGTAATAACGATCGCTTTGTATTTCAG
ATCCTACGTTCGCTGGAGCATGATAACAACGAAGATAAGCCCGGCCCCGGTATGCCGCCACACGGCTGGCGCACGCAATT
CTGGGTGGTTGATCAAAACAACAAAGTGCTGGTTGGCCCGCGAGCACCGATTCCACCAGACGGCACACGGCGGCCCATTA
TGGTCAATGGGGCGGAAGTGGGTGCGGTGATCGCCTCCCCTGTTGAACGACTGACCCGCAATACCGATATCAATTTTGAC
AGACAACAGAGGCAAACCAGTTGGCTGATTGTCGCTTTATCTACCTTGTTAGCGGCGCTGGCGACATTCCCACTGGCGCG
CGGTTTGCTGGCTCCGGTCAAACGACTGGTGGACGGTACACACAAACTGGCAGCGGGCGATTTCACTACTCGCGTAGCCC
CCACCAGCGAAGATGAGTTGGGCAGACTGGCAGAGGATTTCAATCAACTCGCCAGCACACTGGAGAAAAACCAGCAGATG
CGCCGCGATTTTATGGCCGATATCTCCCACGAGCTGCGCACGCCTTTAGCGGTACTGCGCGGCGAACTGGAAGCTATTCA
GGATGGCGTGCGTAAATTCACGCCGGAGACGGTGGCTTCTTTACAGGCAGAGGTCGGTACACTGACCAAACTGGTGGATG
ATCTTCATCAATTGTCGATGTCTGATGAAGGCGCTCTCGCCTATCAAAAAGCACCGGTAGATTTGATCCCACTGCTGGAA
GTGGCGGGCGGCGCATTTCGCGAACGATTCGCCAGCCGTGGCCTGAAACTGCAATTTTCCCTGCCAGACAGTATTACCGT
ATTTGGCGATCGCGACCGTTTAATGCAGTTATTCAATAACTTACTGGAAAACAGCCTGCGCTACACTGACAGCGGCGGTA
GCCTGAAAATCTCTGCCGAGCAGCACGACAAAACGGTGCGACTGACCTTTGCCGACAGCGCGCCGGGCGTCAGTGACGAT
CAGCTACAAAAATTGTTTGAACGTTTTTATCGCACCGAAGGCTCCCGCAACCGAGCCAGCGGCGGTTCCGGGCTGGGGCT
GGCGATTTGCCTGAACATTGTTGAAGCACATAATGGTCGCATTATTGCTGCCCATTCGCCTTTTGGCGGGGTAAGCATTA
CAGTAGAGTTACCGCTGGAACGGGATTTACAGAGAGAAGTATGA

Upstream 100 bases:

>100_bases
GCATGGCGTTTATCATTGCCCTTCCGGCGTTCATCTTTGCCAGAGTGCCGAACGATACGCATCAAAATGTAGCTATTTCG
CGGCGAAAAAGGAGCGCGCA

Downstream 100 bases:

>100_bases
CCGAGTTACCAATCGACGAAAACACGCCACGTATTTTGATCGTGGAAGATGAACCGAAGCTGGGGCAGTTGCTTATTGAT
TATCTGCGTGCTGCGAGCTA

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV

Sequences:

>Translated_467_residues
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
>Mature_467_residues
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=467, Percent_Identity=97.0021413276231, Blast_Score=902, Evalue=0.0,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=29.3103448275862, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=28.3088235294118, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=29.7101449275362, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=27.6679841897233, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787374, Length=299, Percent_Identity=26.4214046822742, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1788713, Length=244, Percent_Identity=28.6885245901639, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=29.2, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788279, Length=292, Percent_Identity=25.6849315068493, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081816, Length=254, Percent_Identity=28.740157480315, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=28.0936454849498, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=307, Percent_Identity=23.7785016286645, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=27.5555555555556, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87082128, Length=292, Percent_Identity=23.6301369863014, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789808, Length=247, Percent_Identity=27.9352226720648, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788549, Length=264, Percent_Identity=25.7575757575758, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789149, Length=320, Percent_Identity=22.8125, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=297, Percent_Identity=28.6195286195286, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI48994928, Length=250, Percent_Identity=24.4, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52071; Mature: 52071

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFDRQQRQTSWLIVALSTLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKAPVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC
>Mature Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFDRQQRQTSWLIVALSTLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSEDELGRLAEDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKAPVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]