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The map label for this gene is baeR

Identifier: 218699328

GI number: 218699328

Start: 990077

End: 990799

Strand: Reverse

Name: baeR

Synonym: ECIAI39_0935

Alternate gene names: 218699328

Gene position: 990799-990077 (Counterclockwise)

Preceding gene: 218699329

Following gene: 218699327

Centisome position: 19.31

GC content: 53.11

Gene sequence:

>723_bases
ATGACCGAGTTACCAATCGACGAAAACACGCCACGTATTTTGATCGTGGAAGATGAACCGAAGCTGGGGCAGTTGCTTAT
TGATTATCTGCGTGCTGCGAGCTATGCGCCGACGCTTATCAGCCACGGCGATCAGGTACTGCCATATGTGCGCCAGACAC
CACCGGATCTGATCCTGTTGGATCTGATGCTCCCTGGCACCGATGGCCTGACGTTGTGTCGGGAGATTCGTCGTTTTTCT
GACATTCCGATCGTGATGGTGACAGCAAAAATCGAAGAGATCGACCGCCTGCTCGGGCTGGAGATTGGCGCAGATGATTA
TATCTGTAAGCCGTACAGCCCACGGGAAGTGGTAGCGCGCGTCAAAACCATTTTGCGCCGTTGCAAACCGCAGCGCGAGT
TGCAGCAACAGGATGCTGAAAGCCCGTTGATTATCGACGAAGGTCGTTTTCAGGCTTCATGGCGCGGAAAAATGCTTGAC
CTGACGCCTGCGGAATTTCGTCTGCTGAAAACGCTCTCTCATGAACCAGGAAAAGTGTTCTCCCGCGAGCAATTGCTCAA
TCATCTTTATGACGACTACCGCGTAGTAACTGACCGCACCATCGACAGCCACATTAAAAACCTGCGTCGCAAGCTGGAAG
CTCTGGACGAAGAGCAGTCTTTTATCCGCGCCGTCTACGGTGTCGGTTATCGCTGGGAAGCCGACGCTTGCCGCATCATT
TAG

Upstream 100 bases:

>100_bases
TTGAAGCACATAATGGTCGCATTATTGCTGCCCATTCGCCTTTTGGCGGGGTAAGCATTACAGTAGAGTTACCGCTGGAA
CGGGATTTACAGAGAGAAGT

Downstream 100 bases:

>100_bases
TTTTAGCGACATGACTTTGTTAGCCGGAGATGGCATTCAGACCAGATCCGGCAACATTATCCCACGCATTGTCGGCTATC
TGACATTATCTCTCCGCCCT

Product: DNA-binding transcriptional regulator BaeR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFS
DIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDEEQSFIRAVYGVGYRWEADACRII

Sequences:

>Translated_240_residues
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFS
DIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDEEQSFIRAVYGVGYRWEADACRII
>Mature_239_residues
TELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSD
IPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDL
TPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDEEQSFIRAVYGVGYRWEADACRII

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=98.75, Blast_Score=482, Evalue=1e-137,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=42.6666666666667, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=40.1785714285714, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1789809, Length=235, Percent_Identity=37.0212765957447, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=37.3333333333333, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.1351351351351, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.6223175965665, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=31.3304721030043, Blast_Score=124, Evalue=6e-30,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.0807174887892, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=34.2222222222222, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=31.8181818181818, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=32.2869955156951, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI145693140, Length=229, Percent_Identity=32.7510917030568, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=30.0448430493274, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27712; Mature: 27581

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILL
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCHHHHHHHHHHCCCCCHHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDEEQSFIRAVYGVGYRWEADACRII
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
>Mature Secondary Structure 
TELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILL
CCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHCCCCCEEEE
DLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVAR
EEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCEECCCCCEECCCCHHHHHHH
VKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLDLTPAEFRLLKTLSHEPGKVF
HHHHHHHCCCHHHHHHHCCCCCEEEECCCCCCCCCCCEEECCHHHHHHHHHHCCCCCHHH
SREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLEALDEEQSFIRAVYGVGYRWEADACRII
HHHHHHHHHHHHHEEHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]