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The map label for this gene is rhtC

Identifier: 218697544

GI number: 218697544

Start: 4391933

End: 4392553

Strand: Direct

Name: rhtC

Synonym: EC55989_4300

Alternate gene names: 218697544

Gene position: 4391933-4392553 (Clockwise)

Preceding gene: 218697543

Following gene: 218697546

Centisome position: 85.2

GC content: 51.69

Gene sequence:

>621_bases
ATGTTGATGTTATTTCTCACCGTCGCCATGGTGCACATTGTGGCGCTTATGAGTCCCGGTCCCGATTTCTTTTTTGTCTC
TCAGACCGCTGTCAGTCGTTCCCGTAAAGAAGCGATGATGGGCGTGCTGGGTATTACCTGCGGCGTTATGGTTTGGGCAG
GGATTGCGTTGCTTGGCCTGCATTTGATTATCGAAAAAATGGCCTGGCTGCATACGCTGATTATGGTTGGCGGTGGCCTG
TATCTCTGCTGGATGGGTTATCAGATGCTGCGCGGCGCGCTGAAAAAAGAGGCGGTTTCTGCACCTGCGCCACAGGTCGA
GCTGGCGAAAAGTGGGCGCAGTTTCCTGAAAGGTTTACTGACCAATCTCGCTAATCCGAAAGCGATTATCTATTTTGGTT
CGGTATTCTCATTGTTTGTCGGTGATAACGTTGGCACTACCGCGCGCTGGGGCATTTTTGCGCTGATCATTGTCGAAACA
CTGGCGTGGTTTACCGTCGTTGCCAGCCTGTTTGCCCTGCCGCAAATGCGCCGTGGTTATCAACGTCTGGCGAAGTGGAT
TGATGGTTTTGCCGGGGCGTTATTTGCCGGATTTGGCATTCATTTGATTATTTCGCGGTGA

Upstream 100 bases:

>100_bases
GATTCGTGCGCATGTCGATGGCGACGACGAAGAGTAGTCAGCAGCATAAAAAAGTGCCAGGATGAAGACTCCGTAAACGT
TTCCCCCGCGAGTCAAATGT

Downstream 100 bases:

>100_bases
TGCCAGACGCGTCTTCAGAGTAAGTCGGATAAGGCGTTTACGCCGCATCCGACATTATTTTTCACGCATGCCTCGCCGAT
GCTAACAGTGCTCCCACCAG

Product: threonine efflux system

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGL
YLCWMGYQMLRGALKKEAVSAPAPQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVET
LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR

Sequences:

>Translated_206_residues
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGL
YLCWMGYQMLRGALKKEAVSAPAPQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVET
LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR
>Mature_206_residues
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGL
YLCWMGYQMLRGALKKEAVSAPAPQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVET
LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR

Specific function: Conducts the efflux of threonine

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family

Homologues:

Organism=Escherichia coli, GI48994978, Length=206, Percent_Identity=100, Blast_Score=412, Evalue=1e-116,
Organism=Escherichia coli, GI1786522, Length=206, Percent_Identity=28.1553398058252, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788099, Length=202, Percent_Identity=28.2178217821782, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RHTC_ECO57 (P0AG39)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   A98223
- RefSeq:   NP_290455.1
- RefSeq:   NP_312780.1
- ProteinModelPortal:   P0AG39
- EnsemblBacteria:   EBESCT00000027855
- EnsemblBacteria:   EBESCT00000057450
- GeneID:   915151
- GeneID:   960336
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5344
- KEGG:   ecs:ECs4753
- GeneTree:   EBGT00050000008903
- HOGENOM:   HBG759042
- OMA:   PAMRRGY
- BioCyc:   ECOL83334:ECS4753-MONOMER
- InterPro:   IPR004778
- InterPro:   IPR001123
- TIGRFAMs:   TIGR00949

Pfam domain/function: PF01810 LysE

EC number: NA

Molecular weight: Translated: 22474; Mature: 22474

Theoretical pI: Translated: 10.57; Mature: 10.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1da4c52c)-; HASH(0x1dde8ac8)-; HASH(0x1db4edb8)-; HASH(0x1c3f2bf4)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGL
CHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEAVSAPAPQVELAKSGRSFLKGLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVETLAWFTVVASLFALPQMRRGY
HHCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLAKWIDGFAGALFAGFGIHLIISR
HHHHHHHHHHHHHHHHHHHHHEEEEH
>Mature Secondary Structure
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGL
CHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEAVSAPAPQVELAKSGRSFLKGLL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVETLAWFTVVASLFALPQMRRGY
HHCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRLAKWIDGFAGALFAGFGIHLIISR
HHHHHHHHHHHHHHHHHHHHHEEEEH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796