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The map label for this gene is pqqL

Identifier: 218695031

GI number: 218695031

Start: 1684777

End: 1687572

Strand: Reverse

Name: pqqL

Synonym: EC55989_1626

Alternate gene names: 218695031

Gene position: 1687572-1684777 (Counterclockwise)

Preceding gene: 218695032

Following gene: 218695030

Centisome position: 32.74

GC content: 46.64

Gene sequence:

>2796_bases
ATGGAGATAATTATGAGAAACCTCTGTTTCTTACTGACGTTAGTGGCAACTCTGTTGCTCCCCGGGCGGCTGATTGCCGC
CGCCTTACCGCAGGATGAAAAGTTAATTACCGGGCAACTGGGCAATGGCTTGCGATATATGATTTATCCGCATGCTCATC
CAAAGGATCAGGTAAATTTATGGCTGCAAATTCATACCGGTTCATTGCAGGAAGAAGACAATGAGCGCGGCGTGGCTCAT
TTTGTAGAACATATGATGTTTAACGGCACAAAAACATGGCCGGGTAATAAAGTCATCGAAACATTTGAGTCAATGGGCCT
GCGTTTTGGTCGCGATGTTAATGCCTATACCAGCTATGACGAAACGGTGTATCAGGTGAGTTTGCCGACTACGCAGAAAC
AAAATCTGCAACAAGTGATGGCAATCTTCAGTGAATGGAGTAATGCCGCAACCTTTGAAAAACTCGAAGTAGACGCTGAA
CGTGGCGTAATTACTGAGGAATGGCGTGCCCATCAGGATGCGAAATGGCGCACCTCTCAGGCGCGCCGCCCTTTCCTGCT
GGCTAATACCCGTAATTTAGACCGTGAACCTATCGGCCTGATGGATACTGTCGCCACGGTCACACCGGCACAATTGCGCC
AATTTTATCAACGCTGGTATCAACCAAATAATATGACCTTTATCGTGGTCGGCGATATCGACAGTAAAGAAGCGCTGGCG
CTGATAAAGGATAATTTAAGTAAGCTTCCGGCTAACAAAGCAGCTGAAAATCGCGTCTGGCCGACAAAAGCCGAAAACCA
CCTGCGCTTTAATATCATTAATGATAAAGAAAACCGGGTGAACGGCATCGCACTCTATTATCGCCTGCCAATGGTACAAG
TGAACGATGAGCAAAGCTTTATCGAACAAGCTGAATGGAGCATGTTAGTTCAGCTGTTCAATCAACGTCTGCAGGAACGC
ATACAGTCGGGCGAGTTGAAGACTATTTCTGGCGGCACTGCGCGCAGCGTTAAAATTGCACCCGATTATCAGTCGCTGTT
TTTCCGTGTAAATGCACGAGACGATAATATGCAGGAAGCTGCGAATGCATTAATGGCAGAGTTGGCAACCATTGATCAGC
ATGGTTTTTCTGCTGAAGAACTCGATGATGTCAAATCTACCCGCCTCACCTGGCTGAAAAATGCGGTTGATCAGCAAGCT
GAACGTGATTTACGTATGCTGACCAGTCGCCTGGCATCCAGCTCATTAAATAATACGCCGTTCTTGTCGCCGGAAGAGAC
ATATCAACTTTCGAAACGTCTGTGGCAGCAAATTACCGTGCAAAGTCTGGCGGAAAAATGGCAGCAGTTAAGAAAGAACC
AGGACGCATTTTGGGAGCAAATGGTAAACAATGAGCTTGCCGCCAAAAAAGCATTGTCTCCTGCGGCTATCCTGGCGCTG
GAAAAAGAGTACGCCAACAAAAAGCTGGCGGCTTACATCTTCCCAGGCAGAAATTTATCGTTAACAGTAGACGCTGACCC
ACAGGCGGAAATTAGCAGCAAAGAAACGCTGGCTGAGAATCTGACATCATTAACACTTTCCAATGGTGCCAGGGTTATTC
TGGCAAAATCCGCGGGTGAAGAGCAAAAGCTACAAATTACTGCCGTATCGAATAAAGGCGATTTAAGTTTCCCTGCGCAG
CAAAAATCACTTATCGCGCTGGCAAATAAAGCAGTAAGCGGAAGCGGCGTTGGTGAGCTCTCCTCTTCCAGCCTGAAACG
CTGGAGTGCGGAAAATTCGGTAACCATGAGCAGTAAAGTCAGTGGCATGAATACGTTGCTCTCCGTTAGCGCGCGGACTA
ATAACCCTGAACCTGGTTTTCAGTTGATTAACCAGCGAATCACCCACAGCACGATTAACGACAATATTTGGGCATCGCTA
CAAAATGCTCAAATTCAGGCGTTGAAAACGCTCGACCAGCGTCCAGCGGAGAAATTCGCCCAGCAGATGTATGAGACGCG
CTATGCTGATGACCGCACGAAATTACTGCAAGAAAATCAGATTGTACAGTTTACTGCCGCAGATGCGCTGGCTGCCGATC
GCCAGTTGTTTTCATCTCCAGCGGATATCACGTTTGTCATTGTCGGTAATGTCTCAGAAGACAAACTCGTGGCGTTAATT
ACGCGTTACTTAGGATCAATCAAACACTCTGATTCGCCATTAGCCGCAGGTAAACCATTAACTCGCGCGACGGACAACGC
ATCGGTTACTGTAAAAGAACAAAATGAACCTGTGGCACAGGTTTCACAGTGGAAGCGTTATGATTCCCGGACACCTGTTA
ATCTGGCGACGCGTATGGCGCTCGATGCTTTTAACGTCGCACTGGCAAAAGATCTACGTGTTAATATTCGTGAACAGGCA
TCTGGAGCATACAGCGTTTCTTCTCGCCTCTCGGTTGATCCTCAGGCCAAAGATATCAGTCATTTGCTGGCTTTTACTTG
TCAACCAGAACGACATGATGAACTGTTAACGTTAGCGAATGAAGTGATGGTTAAGCGTCTGGCTAAAGGGATCAGTGAGC
AAGAACTGAATGAATACCAGCAAAACGTTCAGCGCAGCCTCGATATCCAACAGCGTAGCGTTCAACAATTAGCGAACACT
ATTGTAAATAGTCTTATTCAATATGACGATCCTGCAGCATGGACTGAGCAGGAGCAATTGTTGAAACAAATGACGGTAGA
GAATGTTAACACTGCCGTTAAACAATATCTTTCTCATCCGGTAAATACTTATACCGGAGTATTATTGCCAAAATAA

Upstream 100 bases:

>100_bases
TGGCGACCTACGCCAGTGGCCGTACTTTCTGGCTTGATGTCAGCATGAAATTTTAATAGTTCGGATTTTACTTAACCGGG
TAAATTCGCCCGGTTTTCGC

Downstream 100 bases:

>100_bases
TAACAGCCCCGTCAACACATCGTTGGCGGGGATTTTAGCAATATTCGCTATTTTTATATAATAATTTTATAAATGCGTTC
AAAATAATAATCAAGTACTA

Product: putative membrane-associated peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 931; Mature: 931

Protein sequence:

>931_residues
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLGNGLRYMIYPHAHPKDQVNLWLQIHTGSLQEEDNERGVAH
FVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAE
RGVITEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRVNGIALYYRLPMVQVNDEQSFIEQAEWSMLVQLFNQRLQER
IQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQEAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQA
ERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNELAAKKALSPAAILAL
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGEEQKLQITAVSNKGDLSFPAQ
QKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARTNNPEPGFQLINQRITHSTINDNIWASL
QNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIVQFTAADALAADRQLFSSPADITFVIVGNVSEDKLVALI
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMALDAFNVALAKDLRVNIREQA
SGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANT
IVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLSHPVNTYTGVLLPK

Sequences:

>Translated_931_residues
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLGNGLRYMIYPHAHPKDQVNLWLQIHTGSLQEEDNERGVAH
FVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAE
RGVITEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRVNGIALYYRLPMVQVNDEQSFIEQAEWSMLVQLFNQRLQER
IQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQEAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQA
ERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNELAAKKALSPAAILAL
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGEEQKLQITAVSNKGDLSFPAQ
QKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARTNNPEPGFQLINQRITHSTINDNIWASL
QNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIVQFTAADALAADRQLFSSPADITFVIVGNVSEDKLVALI
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMALDAFNVALAKDLRVNIREQA
SGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANT
IVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLSHPVNTYTGVLLPK
>Mature_931_residues
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLGNGLRYMIYPHAHPKDQVNLWLQIHTGSLQEEDNERGVAH
FVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAE
RGVITEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRVNGIALYYRLPMVQVNDEQSFIEQAEWSMLVQLFNQRLQER
IQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQEAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQA
ERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNELAAKKALSPAAILAL
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGEEQKLQITAVSNKGDLSFPAQ
QKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARTNNPEPGFQLINQRITHSTINDNIWASL
QNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIVQFTAADALAADRQLFSSPADITFVIVGNVSEDKLVALI
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMALDAFNVALAKDLRVNIREQA
SGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANT
IVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLSHPVNTYTGVLLPK

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=216, Percent_Identity=24.537037037037, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1787770, Length=931, Percent_Identity=99.0332975295381, Blast_Score=1897, Evalue=0.0,
Organism=Escherichia coli, GI1789946, Length=467, Percent_Identity=21.1991434689507, Blast_Score=80, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324474, Length=192, Percent_Identity=26.0416666666667, Blast_Score=71, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 104691; Mature: 104691

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLGNGLRYMIYPHAHPKDQVNL
CHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCCEEE
WLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYD
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHCCCCCCCCCCCC
ETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVITEEWRAHQDAKWRTSQ
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHEEHHHCCCCCHHHHCCCCCCHHHHH
ARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
CCCCEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRVNGIALYYRLPMVQVNDEQSF
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECEEEECCHHHH
IEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQEA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHEEEEEECCCCCHHHH
ANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQAERDLRMLTSRLASSSLNNTP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNELAAKKALSPAAILAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHEE
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGE
HHHHCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEECCCC
EQKLQITAVSNKGDLSFPAQQKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKV
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEHHHH
SGMNTLLSVSARTNNPEPGFQLINQRITHSTINDNIWASLQNAQIQALKTLDQRPAEKFA
CCHHHHEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCHHHHHH
QQMYETRYADDRTKLLQENQIVQFTAADALAADRQLFSSPADITFVIVGNVSEDKLVALI
HHHHHHHCCCHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMA
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHH
LDAFNVALAKDLRVNIREQASGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLAN
HHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
EVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LKQMTVENVNTAVKQYLSHPVNTYTGVLLPK
HHHHHHHHHHHHHHHHHCCCCHHHCCCEECC
>Mature Secondary Structure
MEIIMRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLGNGLRYMIYPHAHPKDQVNL
CHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCEEECCCCCCCEEEEECCCCCCCCEEE
WLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYD
EEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHCCCCCCCCCCCC
ETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVITEEWRAHQDAKWRTSQ
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHEEHHHCCCCCHHHHCCCCCCHHHHH
ARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQPNNMTFIVVGDIDSKEALA
CCCCEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHH
LIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRVNGIALYYRLPMVQVNDEQSF
HHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECEEEECCHHHH
IEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQEA
HHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEECCCHHHEEEEEECCCCCHHHH
ANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQAERDLRMLTSRLASSSLNNTP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNELAAKKALSPAAILAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHEE
EKEYANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGE
HHHHCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHEEECCCCEEEEEECCCC
EQKLQITAVSNKGDLSFPAQQKSLIALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKV
CCEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCEEEHHHH
SGMNTLLSVSARTNNPEPGFQLINQRITHSTINDNIWASLQNAQIQALKTLDQRPAEKFA
CCHHHHEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHHHHCCHHHHHH
QQMYETRYADDRTKLLQENQIVQFTAADALAADRQLFSSPADITFVIVGNVSEDKLVALI
HHHHHHHCCCHHHHHHHCCCEEEEECHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHH
TRYLGSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMA
HHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHH
LDAFNVALAKDLRVNIREQASGAYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLAN
HHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
EVMVKRLAKGISEQELNEYQQNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LKQMTVENVNTAVKQYLSHPVNTYTGVLLPK
HHHHHHHHHHHHHHHHHCCCCHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]