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The map label for this gene is mngB

Identifier: 218694155

GI number: 218694155

Start: 782060

End: 784693

Strand: Direct

Name: mngB

Synonym: EC55989_0715

Alternate gene names: 218694155

Gene position: 782060-784693 (Clockwise)

Preceding gene: 218694154

Following gene: 218694156

Centisome position: 15.17

GC content: 49.2

Gene sequence:

>2634_bases
ATGAAAGCGGTATCTCGCGTTCACATCACCCCGCATATGCATTGGGATCGGGAGTGGTATTTCACCACCGAAGAGTCACG
CATTCTGCTGGTCAATAATATGGAAGAGATCCTGTGCCGACTGGAACAGGACAACGAATACAAATATTACGTACTCGACG
GGCAAACGGCGATCCTCGAAGATTATTTCGCGGTGAAACCGGAAAACAAAGACCGCGTGAAGAAACAGGTAGAAGCCGGT
AAGTTGATTATCGGCCCCTGGTATACCCAGACCGATACCACGATTGTTTCTGCGGAATCCATCGTCCGTAATCTGATGTA
CGGAATGCGTGACTGCCTCGCGTTTGGCGAGCCGATGAAAATAGGTTATTTACCGGATTCCTTTGGCATGTCCGGGCAAC
TGCCGCATATCTACAATGGATTTGGCATTACCCGCACTATGTTCTGGCGCGGATGTTCGGAGCGCCACGGTACTGATAAA
ACCGAGTTTTTATGGCAAAGCAGTGACGGTAGCGAAGTGACGGCGCAGGTGCTGCCGTTGGGTTATGCCATCGGTAAGTA
CTTACCTGCCGACGAAAACGGATTACGCAAACGCCTCGACAGTTATTTTGACGTGCTGGAAAAAGCGTCTGTAACCAAAG
AGATTTTATTGCCGAATGGTCATGACCAGATGCCATTGCAGCAAAATATCTTCGAAGTGATGGAGAAACTTCGCGAAATT
TATCCTCAACGAAAGTTTGTGATGAGCCGCTTTGAAGAGGTATTCGAGCAGATCGAAGCGCAGCGTGAAAGTCTGGCCAC
CCTGAAAGGTGAATTTATCGATGGCAAATATATGCGCGTACATCGCACCATCGGTTCCACGCGCATGGATATCAAAATTG
CCCACGCACGTATTGAAAATAAGATTGTTAATCTGCTGGAACCGCTGGCAACGCTGGCCTGGACGTTGGGTTTTGAATAC
CACCACGGCTTGCTGGAGAAAATGTGGAAAGAGATCTTAAAAAATCATGCCCACGACAGTATCGGTTGTTGTTGCAGTGA
CAAAGTTCATCGCGAAATTGTCGCCCGCTTCGAACTGGCTGAAGACATGGCGGATAATCTGCTGCGTTTCTACATGCGCA
AAATTGCCGATAACATGCCACAGAGTGATGCCGACAAACTCGTGCTGTTTAACCTGATGCCCTGGCCGCGGGAAGAAGTT
ATTAACACCACTGTGCGGCTGCGCGCCAGCCAGTTTAATCTACGAGACGATCGCGGTCAGCCTGTACCGTATTTTATTCG
CCATGCCCGTGAGATCGATCCAGGCCTAATCGATCGGCAAATAGTTCATTACGGTAATTACGATCCCTTTATGGAGTTTG
ATATACAGATCAACCAGATTGTCCCTTCTATGGGCTATCGCACGCTTTATATCGAAGCGAATCAGCCTGGCAACGTGATT
GCGGCAAAAAGTGACGCTGAAGGGATACTGGAAAATGCTTTCTGGCAAATTGCGCTCAATGAGGATGGAACGCTACAACT
GGTAGATAAAGATAGCGGTGTGCGCTATGACCGGGTGTTGCAAATTGAAGAAAGCTCTGATGATGGTGATGAATATGACT
ATTCACCCGCAAAAGAAGAGTGGGTAATGACTTCTGCAACAGCGAAACCGCAATGCGAGATTACTCATGAGGCCTGGCAG
AGCAGGGCTGTTATCCGCTATGACATGGCGGTGCCGCTCAATTTGTTGGAACGAAGCGTCCGGCAATCCACGGGCAGAGT
AGGGGTGGAGATGGTTGTCACTCTGAGTCATAACAGCAGACGTATTGATGTGGATATCAACCTTGATAACCAGGCTGACG
ATCATCGCCTTCGCGTCCTGATCCCTACATCTTTTAACACCGATAGTGTTCTGGCAGATACCCAGTTTGGTTCGCTAACG
CGCCCCGTGAACGACAGTGCAATGAACAACTGGCAGCAAGAAGGCTGGAAAGAAGCGCCGGTTCCGGTATGGAATATGCT
CAACTATGCAGCCTTACAGGAAGGGCGTAACGGCATGGCTGTCTTTAGCGAAGGGCTACGTGAATTTGAAGTCATCGGTG
AAGAGAAGAAAACCTTTGCCATTACGTTGCTGCGTGGCGTGGGCTTACTGGGCAAAGAAGATCTGTTTTTAAGGCCTGGG
CGGCCTTCGGGAATTAAAATGCCAGTCCCGGACTCACAACTACGTGGTCTGCTTTCTTGTCGCCTAAGTTTATTGAGTTA
TACCGGTACGCCAACCGCCGCTGGTGTAGCTCAGCAGGCGCGAGCATGGCTGACTCCAGTACAGTGTTACAACAAAATCC
CATGGGATGCGATGAAGCTCAACAAAGCCGGATTCAACGTGCCGGAAAGTTATAGTTTGTTGAAAATGCCCCCAGTGGGA
TGCCTGATAAGCGCACTTAAGAAAGCTGAAGACCGACAAGAAGTGATTTTACGGCTGTTTAATCCGGCTGAATCAGCAAC
CTGTGATGCGACTGTTGCTTTCAGTCGCGAGGTGATTTCTTGCTCAGAAACGATGATGGATGAACACATTACCACCGAGG
AAAATCAAGGTTCAAATCTATCGGGGCCTTTTTTACCCGGCCAGTCACGGACGTTCAGTTACCGGCTTGCCTGA

Upstream 100 bases:

>100_bases
CAATCTCGACTGCAATTCTCCTGATCTGGCGGCGTCACGCGGTTAAGCATGGCAACTATCTGACTGATGGCGTAATGCCA
TAAACAAAAAGGAAACGACG

Downstream 100 bases:

>100_bases
ATAGCAATCAAACCGAAGCCACATATGCGCGGCCAGATTGTTGACAAAGGGCGCTTTGTTCATGCCGGATACGGCATGAA
CGCTTTATTCGGTCTACAAA

Product: alpha-mannosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 877; Mature: 877

Protein sequence:

>877_residues
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILEDYFAVKPENKDRVKKQVEAG
KLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMEKLREI
YPQRKFVMSRFEEVFEQIEAQRESLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEY
HHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELAEDMADNLLRFYMRKIADNMPQSDADKLVLFNLMPWPREEV
INTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVI
AAKSDAEGILENAFWQIALNEDGTLQLVDKDSGVRYDRVLQIEESSDDGDEYDYSPAKEEWVMTSATAKPQCEITHEAWQ
SRAVIRYDMAVPLNLLERSVRQSTGRVGVEMVVTLSHNSRRIDVDINLDNQADDHRLRVLIPTSFNTDSVLADTQFGSLT
RPVNDSAMNNWQQEGWKEAPVPVWNMLNYAALQEGRNGMAVFSEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLFLRPG
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKLNKAGFNVPESYSLLKMPPVG
CLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA

Sequences:

>Translated_877_residues
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILEDYFAVKPENKDRVKKQVEAG
KLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMEKLREI
YPQRKFVMSRFEEVFEQIEAQRESLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEY
HHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELAEDMADNLLRFYMRKIADNMPQSDADKLVLFNLMPWPREEV
INTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVI
AAKSDAEGILENAFWQIALNEDGTLQLVDKDSGVRYDRVLQIEESSDDGDEYDYSPAKEEWVMTSATAKPQCEITHEAWQ
SRAVIRYDMAVPLNLLERSVRQSTGRVGVEMVVTLSHNSRRIDVDINLDNQADDHRLRVLIPTSFNTDSVLADTQFGSLT
RPVNDSAMNNWQQEGWKEAPVPVWNMLNYAALQEGRNGMAVFSEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLFLRPG
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKLNKAGFNVPESYSLLKMPPVG
CLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA
>Mature_877_residues
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILEDYFAVKPENKDRVKKQVEAG
KLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMEKLREI
YPQRKFVMSRFEEVFEQIEAQRESLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEY
HHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELAEDMADNLLRFYMRKIADNMPQSDADKLVLFNLMPWPREEV
INTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVI
AAKSDAEGILENAFWQIALNEDGTLQLVDKDSGVRYDRVLQIEESSDDGDEYDYSPAKEEWVMTSATAKPQCEITHEAWQ
SRAVIRYDMAVPLNLLERSVRQSTGRVGVEMVVTLSHNSRRIDVDINLDNQADDHRLRVLIPTSFNTDSVLADTQFGSLT
RPVNDSAMNNWQQEGWKEAPVPVWNMLNYAALQEGRNGMAVFSEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLFLRPG
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKLNKAGFNVPESYSLLKMPPVG
CLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA

Specific function: May hydrolyze mannosyl-D-glycerate to mannose-6- phosphate and glycerate [H]

COG id: COG0383

COG function: function code G; Alpha-mannosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 38 family [H]

Homologues:

Organism=Homo sapiens, GI46852164, Length=410, Percent_Identity=24.1463414634146, Blast_Score=84, Evalue=6e-16,
Organism=Escherichia coli, GI1786952, Length=877, Percent_Identity=97.7194982896237, Blast_Score=1777, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321282, Length=443, Percent_Identity=23.9277652370203, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR011330
- InterPro:   IPR011682
- InterPro:   IPR015341
- InterPro:   IPR000602 [H]

Pfam domain/function: PF09261 Alpha-mann_mid; PF01074 Glyco_hydro_38; PF07748 Glyco_hydro_38C [H]

EC number: NA

Molecular weight: Translated: 100138; Mature: 100138

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILE
CCCCCEEEECCCCCCCCEEEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCHHHH
DYFAVKPENKDRVKKQVEAGKLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMK
HHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCE
IGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDKTEFLWQSSDGSEVTAQVLPL
EECCCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCCCHHEEEECCCCCCEEHHHHHH
GYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMEKLREI
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
YPQRKFVMSRFEEVFEQIEAQRESLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCEEEEEEHHHHHHH
KIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EDMADNLLRFYMRKIADNMPQSDADKLVLFNLMPWPREEVINTTVRLRASQFNLRDDRGQ
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHCHHHEEEEHHCCCCCCCCC
PVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVI
CCHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEEEEEEHHCCCCCCEEEEEEECCCCCEE
AAKSDAEGILENAFWQIALNEDGTLQLVDKDSGVRYDRVLQIEESSDDGDEYDYSPAKEE
EECCCHHHHHCCCEEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCHH
WVMTSATAKPQCEITHEAWQSRAVIRYDMAVPLNLLERSVRQSTGRVGVEMVVTLSHNSR
EEEEECCCCCCEEEEHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEECCCE
RIDVDINLDNQADDHRLRVLIPTSFNTDSVLADTQFGSLTRPVNDSAMNNWQQEGWKEAP
EEEEEEECCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCC
VPVWNMLNYAALQEGRNGMAVFSEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLFLRPG
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCEEEECC
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHEE
NKAGFNVPESYSLLKMPPVGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVIS
CCCCCCCCCCCCEEECCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHH
CSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECC
>Mature Secondary Structure
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILE
CCCCCEEEECCCCCCCCEEEEECCCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCHHHH
DYFAVKPENKDRVKKQVEAGKLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMK
HHHCCCCCCHHHHHHHHHCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCE
IGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDKTEFLWQSSDGSEVTAQVLPL
EECCCCCCCCCCCCCHHCCCCCHHHHHHHCCCCCCCCCCCHHEEEECCCCCCEEHHHHHH
GYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMEKLREI
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
YPQRKFVMSRFEEVFEQIEAQRESLATLKGEFIDGKYMRVHRTIGSTRMDIKIAHARIEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCEEEEEEHHHHHHH
KIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
EDMADNLLRFYMRKIADNMPQSDADKLVLFNLMPWPREEVINTTVRLRASQFNLRDDRGQ
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHCHHHEEEEHHCCCCCCCCC
PVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQINQIVPSMGYRTLYIEANQPGNVI
CCHHHHHHHHCCCCCHHHHHHHCCCCCCCCEEEEEEEEHHCCCCCCEEEEEEECCCCCEE
AAKSDAEGILENAFWQIALNEDGTLQLVDKDSGVRYDRVLQIEESSDDGDEYDYSPAKEE
EECCCHHHHHCCCEEEEEECCCCEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCHH
WVMTSATAKPQCEITHEAWQSRAVIRYDMAVPLNLLERSVRQSTGRVGVEMVVTLSHNSR
EEEEECCCCCCEEEEHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEEEECCCE
RIDVDINLDNQADDHRLRVLIPTSFNTDSVLADTQFGSLTRPVNDSAMNNWQQEGWKEAP
EEEEEEECCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCCCCCHHHHHHHHHCCCCCCC
VPVWNMLNYAALQEGRNGMAVFSEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLFLRPG
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCCCEEEECC
RPSGIKMPVPDSQLRGLLSCRLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKL
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCHHEE
NKAGFNVPESYSLLKMPPVGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVIS
CCCCCCCCCCCCEEECCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCEEHHHHHHHHH
CSETMMDEHITTEENQGSNLSGPFLPGQSRTFSYRLA
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 9063979 [H]