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The map label for this gene is mngA

Identifier: 218694154

GI number: 218694154

Start: 780066

End: 782042

Strand: Direct

Name: mngA

Synonym: EC55989_0714

Alternate gene names: 218694154

Gene position: 780066-782042 (Clockwise)

Preceding gene: 218694152

Following gene: 218694155

Centisome position: 15.13

GC content: 54.63

Gene sequence:

>1977_bases
ATGGTATTGTTTTATCGGGCGCACTGGCGCGACTATAAAAACGATCAAGTGAGGATCATGATGAATCTGACGACTCTGAC
CCACCGCGATGCGTTGTGTCTGAATGCGCGCTTTACCAGCCGTGAAGAGGCCATCCACGCGTTGACTCAACGTCTTGCTG
CTCTGGGGAAAATTTCCAGTACTGAGCAATTTCTGGAAGAAGTGTATCGCCGTGAAAGCCTTGGCCCGACCGCCTTAGGT
GAAGGGTTGGCTGTGCCGCATGGCAAAACTGCTGCGGTAAAAGAAGCGGCGTTTGCGGTCGCCACACTCAGCGAGCCGCT
TCAGTGGGAAGGCGTTGATGGCCCGGAAGCGGTTGATTTAGTGGTGCTGCTGGCGATTCCCCCCAATGAAGCGGGTACTA
CGCATATGCAACTGCTGACAGCGCTGACCACGCGCCTGGCGGATGATGAGATTCGGGCGCGTATACAGTCGGCGACGACG
CCTGATGAGTTGCTCTCGGCGCTGGATGACAAGGGAGACACGCAACCTTCTGCCTCTTTTTCCAACGCGCCAACTATCGT
CTGCGTAACGGCCTGTCCGGCGGGTATTGCTCACACCTATATGGCTGCGGAATATCTGGAAAAAGCCGGACGCAAACTCG
GCGTAAATGTTTACGTTGAAAAACAAGGCGCTAACGGCATTGAAGGGCGTTTAACGGCGGATCAACTCAATAGTGCAACC
GCCTGTATTTTTGCGGCTGAAGTCGCCATCAAGGAGAGTGAGCGTTTTAATGGCATTCCCGCGCTTTCAGTGCGTGTTGC
CGAGCCGATTCGCCATGCAGAAGCGTTGATGCAACAAGCGCTTACCCTCAAGCGTAGCGATGAGACGCGTACCGTACAGC
AAGATACGCAACCGGTGAAAAGTGTCAAAACGGAGCTGAAACAGGCACTGTTGAGCGGAATCTCTTTTGCCGTACCGTTG
ATTGTCGCGGGGGGCACGGTGCTGGCGGTCGCGGTATTACTGTCGCAAATCTTCGGGCTACAAGATCTGTTTAATGAAGA
AAACTCCTGGCTGTGGATGTACCGCAAGCTGGGCGGCGGGCTGCTCGGAATTTTGATGGTACCGGTGCTCGCGGCCTATA
CCGCCTATTCTCTGGCAGATAAACCGGCGTTAGCGCCAGGCTTTGCGGCTGGACTTGCCGCCAACATGATCGGCTCCGGG
TTTCTCGGCGCGGTCGTTGGCGGATTGATAGCCGGTTACTTGATGCGCTGGGTGAAAAATCACTTGCGTCTTAGCAGTAA
ATTCAATGGATTCCTGACTTTTTATCTCTACCCGGTGCTCGGTACGTTGGGAGCGGGCAGTCTGATGCTGTTTGTGGTGG
GAGAACCTGTCGCCTGGATCAATAACTCGCTTACCGCCTGGCTGAACGGTCTGTCAGGAAGTAACGCGCTGTTGCTGGGT
GCCATTCTCGGTTTTATGTGTTCCTTTGACCTTGGAGGGCCAGTGAACAAAGCCGCTTATGCATTCTGCCTGGGCGCAAT
GGCGAACGGCGTTTACGGCCCGTATGCCATTTTCGCCTCCGTCAAAATGGTTTCGGCATTTACCGTAACCGCTTCCACGA
TGCTCGCACCGCGCCTGTTTAAAGAGTTTGAAATTGAGACCGGGAAATCCACCTGGCTGTTAGGGCTGGCAGGTATTACC
GAAGGGGCGATCCCGATGGCGATTGAAGATCCGCTGCGGGTTATTGGTTCGTTTGTGCTGGGCTCTATGGTAACGGGCGC
TATTGTCGGTGCGATGAATATCGGCCTTTCGACACCCGGTGCCGGCATTTTCTCGCTCTTTTTACTTCATGATAATGGCG
CGGGCGGTGTTATGGCGGCAATTGGCTGGTTTGGTGCGGCATTGGTGGGGGCTGCAATCTCGACTGCAATTCTCCTGATC
TGGCGGCGTCACGCGGTTAAGCATGGCAACTATCTGACTGATGGCGTAATGCCATAA

Upstream 100 bases:

>100_bases
TCTCATTAATACGAATTTAGCCATTATGCCCGATAAATTCATCCTGTAAATAATACAAATACAATACAAATAATTTCAAT
CAAGTGAAATTGATCACATA

Downstream 100 bases:

>100_bases
ACAAAAAGGAAACGACGATGAAAGCGGTATCTCGCGTTCACATCACCCCGCATATGCATTGGGATCGGGAGTGGTATTTC
ACCACCGAAGAGTCACGCAT

Product: PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC

Products: NA

Alternate protein names: Putative PTS system EIIABC component; Phosphotransferase enzyme IIA component; PTS system EIIA component; Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component [H]

Number of amino acids: Translated: 658; Mature: 658

Protein sequence:

>658_residues
MVLFYRAHWRDYKNDQVRIMMNLTTLTHRDALCLNARFTSREEAIHALTQRLAALGKISSTEQFLEEVYRRESLGPTALG
EGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATT
PDELLSALDDKGDTQPSASFSNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSAT
ACIFAAEVAIKESERFNGIPALSVRVAEPIRHAEALMQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPL
IVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSG
FLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLG
AILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGIT
EGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLI
WRRHAVKHGNYLTDGVMP

Sequences:

>Translated_658_residues
MVLFYRAHWRDYKNDQVRIMMNLTTLTHRDALCLNARFTSREEAIHALTQRLAALGKISSTEQFLEEVYRRESLGPTALG
EGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATT
PDELLSALDDKGDTQPSASFSNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSAT
ACIFAAEVAIKESERFNGIPALSVRVAEPIRHAEALMQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPL
IVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSG
FLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLG
AILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGIT
EGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLI
WRRHAVKHGNYLTDGVMP
>Mature_658_residues
MVLFYRAHWRDYKNDQVRIMMNLTTLTHRDALCLNARFTSREEAIHALTQRLAALGKISSTEQFLEEVYRRESLGPTALG
EGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATT
PDELLSALDDKGDTQPSASFSNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSAT
ACIFAAEVAIKESERFNGIPALSVRVAEPIRHAEALMQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPL
IVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSG
FLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLG
AILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGIT
EGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLI
WRRHAVKHGNYLTDGVMP

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1786951, Length=658, Percent_Identity=99.3920972644377, Blast_Score=1323, Evalue=0.0,
Organism=Escherichia coli, GI1788492, Length=557, Percent_Identity=33.0341113105925, Blast_Score=269, Evalue=4e-73,
Organism=Escherichia coli, GI87082348, Length=480, Percent_Identity=32.9166666666667, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1790386, Length=289, Percent_Identity=39.1003460207612, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1788729, Length=392, Percent_Identity=27.2959183673469, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1790387, Length=94, Percent_Identity=44.6808510638298, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788730, Length=103, Percent_Identity=33.9805825242718, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI48994992, Length=153, Percent_Identity=24.8366013071895, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788726, Length=136, Percent_Identity=27.2058823529412, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789597, Length=159, Percent_Identity=27.6729559748428, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 69786; Mature: 69786

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLFYRAHWRDYKNDQVRIMMNLTTLTHRDALCLNARFTSREEAIHALTQRLAALGKISS
CEEEEEECCCCCCCCCEEEEEEEEHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCC
TEQFLEEVYRRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDL
HHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCEEE
VVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDKGDTQPSASF
EEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
SNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSAT
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEECCEEEEEECCCCCCCCCEEHHHHCCHH
ACIFAAEVAIKESERFNGIPALSVRVAEPIRHAEALMQQALTLKRSDETRTVQQDTQPVK
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEHHHCCH
LLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKN
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
HLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLG
HHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCHHHHHCCCCCCCHHHHH
AILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPG
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLIWRRHAVKHGNYLTDGVMP
CHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVLFYRAHWRDYKNDQVRIMMNLTTLTHRDALCLNARFTSREEAIHALTQRLAALGKISS
CEEEEEECCCCCCCCCEEEEEEEEHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCC
TEQFLEEVYRRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDL
HHHHHHHHHHHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCCCEEE
VVLLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDKGDTQPSASF
EEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
SNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNSAT
CCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEECCEEEEEECCCCCCCCCEEHHHHCCHH
ACIFAAEVAIKESERFNGIPALSVRVAEPIRHAEALMQQALTLKRSDETRTVQQDTQPVK
HHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
SVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHCCCCCEEEEEHHHCCH
LLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKN
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
HLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNGLSGSNALLLG
HHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCHHHHHCCCCCCCHHHHH
AILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPG
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
AGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLIWRRHAVKHGNYLTDGVMP
CHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9063979; 9278503; 8905232 [H]