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The map label for this gene is traA

Identifier: 218692896

GI number: 218692896

Start: 87861

End: 88220

Strand: Reverse

Name: traA

Synonym: p1ECUMN_0111

Alternate gene names: 218692896

Gene position: 88220-87861 (Counterclockwise)

Preceding gene: 218692897

Following gene: 218692895

Centisome position: 72.13

GC content: 45.83

Gene sequence:

>360_bases
ATGAATACTGTTTTAAGTGTTCAGGGTGCTTCTGCGCCCGTTGAAAAGAAATCGTTTTTTTCTAAATTCACTTGTCTGAA
TATGCTTCGCCTGGTTCGTGCAGTGATCCCGGTTGCTGTTCTGATGATGTTGTTCCCTGAGTTAGCTATGGCTGCTGGTA
AAGGCGACCTGATGGCTAAAGGTCAGGAAACGGTTAAGGCGACCTTCGGTAAGAACTCCAGTATCGTTAAATGGATTGTT
CTGGCTGAGGTGCTGGTCGGTGCGGTCATGTACATGATGACCAAAAACATCAAGTTCCTGGTCGGCTTTGCCATACTCTC
TGTATTTATTGCAGTAGGTATGTCTGTTGCCGGATTCTGA

Upstream 100 bases:

>100_bases
ACCCTGTTCCATGGCTCCAGATGACAAACATGATCTCATATCAGGGACTTGTTCGCACCTTCCTTAGTTTTCATCTGTCA
ATATTAATCAGAGGAATCAT

Downstream 100 bases:

>100_bases
CAGGAAATAAAACGATGTCGGGAGACGAGAATAAACTTAAGAAATATCGTTTCCCGGAAACACTGACCAACCAGAGCCGC
TGGTTTGGCCTGCCACTGGA

Product: conjugal transfer pilin subunit TraA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MNTVLSVQGASAPVEKKSFFSKFTCLNMLRLVRAVIPVAVLMMLFPELAMAAGKGDLMAKGQETVKATFGKNSSIVKWIV
LAEVLVGAVMYMMTKNIKFLVGFAILSVFIAVGMSVAGF

Sequences:

>Translated_119_residues
MNTVLSVQGASAPVEKKSFFSKFTCLNMLRLVRAVIPVAVLMMLFPELAMAAGKGDLMAKGQETVKATFGKNSSIVKWIV
LAEVLVGAVMYMMTKNIKFLVGFAILSVFIAVGMSVAGF
>Mature_119_residues
MNTVLSVQGASAPVEKKSFFSKFTCLNMLRLVRAVIPVAVLMMLFPELAMAAGKGDLMAKGQETVKATFGKNSSIVKWIV
LAEVLVGAVMYMMTKNIKFLVGFAILSVFIAVGMSVAGF

Specific function: Propilin is the precursor of the pilus subunit, pilin, that forms conjugative pili, the filamentous surface appendages required for cell-to-cell contact during the earlier stages of bacterial conjugation, and that retract after contact is established. Mat

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein. Secreted. Note=Propilin is directed to the inner membrane, where it is cleaved and acetylated. Mature pilin forms filaments that are secreted to form the conjugative pilus (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the traA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008873 [H]

Pfam domain/function: PF05513 TraA [H]

EC number: NA

Molecular weight: Translated: 12770; Mature: 12770

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
8.4 %Met     (Translated Protein)
9.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
8.4 %Met     (Mature Protein)
9.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVLSVQGASAPVEKKSFFSKFTCLNMLRLVRAVIPVAVLMMLFPELAMAAGKGDLMAK
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHC
GQETVKATFGKNSSIVKWIVLAEVLVGAVMYMMTKNIKFLVGFAILSVFIAVGMSVAGF
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTVLSVQGASAPVEKKSFFSKFTCLNMLRLVRAVIPVAVLMMLFPELAMAAGKGDLMAK
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHC
GQETVKATFGKNSSIVKWIVLAEVLVGAVMYMMTKNIKFLVGFAILSVFIAVGMSVAGF
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2999074; 2836369 [H]