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The map label for this gene is resA [H]

Identifier: 218692826

GI number: 218692826

Start: 30478

End: 31032

Strand: Reverse

Name: resA [H]

Synonym: p1ECUMN_0037

Alternate gene names: 218692826

Gene position: 31032-30478 (Counterclockwise)

Preceding gene: 218692827

Following gene: 218692825

Centisome position: 25.37

GC content: 57.48

Gene sequence:

>555_bases
TTGGGCAGTTTGCCGACCGTATTCTGCGGCTGCAACACGGTAAATATCTGGGTGAGGAGGCCAATCAACATGCGCTGGCA
TAATGTGCTGTTACTCGCGGCGGCGATCCTGATAAGCGGGTGTAAAGAAGAAAAGCTGGCGGTCGGGGCACCGGCCCCGG
CGCTGGCGGCGTTTGATCTGCAAGGCCAGGAGTCAGGCCTTGAACGCTGGCAAGGAAAGGCGGTGTACCTGAATTTTTGG
TCTGCGGGATGCGGGGGGTGCCTAGCGGAAATGGACACGCTGGAAGCGCTGAGCAAAAAATGGGGCGATAAAGTGGTGGT
TGTGGCGGTCAATACCGACCCTGAAACGGTCAGGATCAACGATCTGCTGGCAAAACATCAGATAACCTATCCGGTGGTGC
GCGATCAGCTCAACATTACCCAGGAACGTTATCAGGTGATCGGCACGCCGACCTCCGTACTGATTGACTCCGAAGGACGC
GTTCTGGAGCTACACCAGGGTATGCGTAAGCCGTCTGAGTTAGAGGCCACGTTTGCGCGCCTGGCGGCGCGATGA

Upstream 100 bases:

>100_bases
GGCAACCTGGATGAAGAGAATGAGCAGCGGGTGCTGGATCTGCTCACCGATCTGCATCGTCAGGGGCGCACGATTGTGAT
GGTGACGCACAACCCTGCGC

Downstream 100 bases:

>100_bases
ACGACGCGTACGGAGAGATACCCAATGGCATTTATCTGGAACGACGAAAGCCTTGCGATTCTGCGGGAAAACGCGGGCAT
CCTCACGACAGAGCAGATAG

Product: thioredoxin-family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MGSLPTVFCGCNTVNIWVRRPINMRWHNVLLLAAAILISGCKEEKLAVGAPAPALAAFDLQGQESGLERWQGKAVYLNFW
SAGCGGCLAEMDTLEALSKKWGDKVVVVAVNTDPETVRINDLLAKHQITYPVVRDQLNITQERYQVIGTPTSVLIDSEGR
VLELHQGMRKPSELEATFARLAAR

Sequences:

>Translated_184_residues
MGSLPTVFCGCNTVNIWVRRPINMRWHNVLLLAAAILISGCKEEKLAVGAPAPALAAFDLQGQESGLERWQGKAVYLNFW
SAGCGGCLAEMDTLEALSKKWGDKVVVVAVNTDPETVRINDLLAKHQITYPVVRDQLNITQERYQVIGTPTSVLIDSEGR
VLELHQGMRKPSELEATFARLAAR
>Mature_183_residues
GSLPTVFCGCNTVNIWVRRPINMRWHNVLLLAAAILISGCKEEKLAVGAPAPALAAFDLQGQESGLERWQGKAVYLNFWS
AGCGGCLAEMDTLEALSKKWGDKVVVVAVNTDPETVRINDLLAKHQITYPVVRDQLNITQERYQVIGTPTSVLIDSEGRV
LELHQGMRKPSELEATFARLAAR

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 20230; Mature: 20098

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSLPTVFCGCNTVNIWVRRPINMRWHNVLLLAAAILISGCKEEKLAVGAPAPALAAFDL
CCCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEC
QGQESGLERWQGKAVYLNFWSAGCGGCLAEMDTLEALSKKWGDKVVVVAVNTDPETVRIN
CCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEHH
DLLAKHQITYPVVRDQLNITQERYQVIGTPTSVLIDSEGRVLELHQGMRKPSELEATFAR
HHHHHHCCCCHHHHHHHHHCHHHHEEECCCEEEEECCCCCEEEEHHCCCCCHHHHHHHHH
LAAR
HHCC
>Mature Secondary Structure 
GSLPTVFCGCNTVNIWVRRPINMRWHNVLLLAAAILISGCKEEKLAVGAPAPALAAFDL
CCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEC
QGQESGLERWQGKAVYLNFWSAGCGGCLAEMDTLEALSKKWGDKVVVVAVNTDPETVRIN
CCCHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEHH
DLLAKHQITYPVVRDQLNITQERYQVIGTPTSVLIDSEGRVLELHQGMRKPSELEATFAR
HHHHHHCCCCHHHHHHHHHCHHHHEEECCCEEEEECCCCCEEEEHHCCCCCHHHHHHHHH
LAAR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA