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The map label for this gene is siaP [H]

Identifier: 218692741

GI number: 218692741

Start: 5158203

End: 5159174

Strand: Reverse

Name: siaP [H]

Synonym: ECED1_5223

Alternate gene names: 218692741

Gene position: 5159174-5158203 (Counterclockwise)

Preceding gene: 218692743

Following gene: 218692740

Centisome position: 99.03

GC content: 43.62

Gene sequence:

>972_bases
ATGAGCAAAATAATAGCGATGCTAATTACTGTCAGTACCCTTTTTTTACCGTCAATAATCCAGGCAAAACCTATTTCAAT
AAAAGTTGCCTATGAAAATAACCCTGGAGAACCCCTGGATGTGGTCATGCGTTACTGGGCAGACCTATTAAATAAAAAAA
GTAATGGCGAAATAACACTTGCGCTCTATCCCAGCTCCCAATTGGGATCAAAACAGGATGTCACCGAGCAAGCCATAATG
GGCATGAATGTCATAACCTTGAGTGATGTGGCTTTTCTTGCCGATTATGAACCCGATTTGGGGATTTTGTTTGGACCGTA
TCTGACTGACGATCCGCAAAAACTGTTCAAAATATATGAAAGCGACTGGTTTAAACAAAAAAATGAAAGTCTGAAGAAAA
AGGGAATTCATGTGGTAATGAATAATTATCTCTATGGCACTCGACAGATTATTTCGAAAAAACCCATTCGCACCGTTGAC
GATCTCGCAGGTTTAAAAATTCGCGTTCCTAATAACGTCATGCAAATAAAAGCCATTCAGGCGATGGGGGCAACACCAAC
TCCCATGCCATTAGGCGAAGTTTATCCCGCATTAACCCAGGGCGTTATTGACGGCGTAGAAAACCCAATTTCAGTGCTGC
AAGGGCAAAAACTGTATGAGCAGGCAAGATATCTGACAATGGTTAACTACCTGACAAATACCTCAGTGTGGATAGGTGGT
GAAGCCTTCTTTGGCACCCTTTCACCAGAACAACTGGAGATGATCCACCAGACCGGCTATGAAGCGGGTGTCTATAGCCA
GAAACTCACTCTTGAGCGTGATGCCGAAATGTTGAAAACCATGCAGGCAGCCGGCGTCGAAGTGATCTATCCCGATACTG
GACCATTCCAGAAGAAAGCACGCGAAGTTTACTCTCAATTCCCGGAATGGACACCAGGTCTGTACGAAACCATTCAACAG
CAACTGCAATAA

Upstream 100 bases:

>100_bases
CTATTCGCTGACTACTTTTCAGTAATGACTGCTTTTTCATAAGGTTTCACTCCCGACAACAATGTTGGAGTTTTATTTCC
TTAGCATGGAGTAAGTAAAG

Downstream 100 bases:

>100_bases
GCATTAATGCTCAGCGTCCTGCCTCATCTCTCTTAGGCAGGACACGCACTAACAGGAGGTTTCATGCGTCTTTTTGGCAA
AGTGGCAGAATTTAGTGCTG

Product: putative C4-dicarboxylate-binding periplasmic protein (dctP-like)

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MSKIIAMLITVSTLFLPSIIQAKPISIKVAYENNPGEPLDVVMRYWADLLNKKSNGEITLALYPSSQLGSKQDVTEQAIM
GMNVITLSDVAFLADYEPDLGILFGPYLTDDPQKLFKIYESDWFKQKNESLKKKGIHVVMNNYLYGTRQIISKKPIRTVD
DLAGLKIRVPNNVMQIKAIQAMGATPTPMPLGEVYPALTQGVIDGVENPISVLQGQKLYEQARYLTMVNYLTNTSVWIGG
EAFFGTLSPEQLEMIHQTGYEAGVYSQKLTLERDAEMLKTMQAAGVEVIYPDTGPFQKKAREVYSQFPEWTPGLYETIQQ
QLQ

Sequences:

>Translated_323_residues
MSKIIAMLITVSTLFLPSIIQAKPISIKVAYENNPGEPLDVVMRYWADLLNKKSNGEITLALYPSSQLGSKQDVTEQAIM
GMNVITLSDVAFLADYEPDLGILFGPYLTDDPQKLFKIYESDWFKQKNESLKKKGIHVVMNNYLYGTRQIISKKPIRTVD
DLAGLKIRVPNNVMQIKAIQAMGATPTPMPLGEVYPALTQGVIDGVENPISVLQGQKLYEQARYLTMVNYLTNTSVWIGG
EAFFGTLSPEQLEMIHQTGYEAGVYSQKLTLERDAEMLKTMQAAGVEVIYPDTGPFQKKAREVYSQFPEWTPGLYETIQQ
QLQ
>Mature_322_residues
SKIIAMLITVSTLFLPSIIQAKPISIKVAYENNPGEPLDVVMRYWADLLNKKSNGEITLALYPSSQLGSKQDVTEQAIMG
MNVITLSDVAFLADYEPDLGILFGPYLTDDPQKLFKIYESDWFKQKNESLKKKGIHVVMNNYLYGTRQIISKKPIRTVDD
LAGLKIRVPNNVMQIKAIQAMGATPTPMPLGEVYPALTQGVIDGVENPISVLQGQKLYEQARYLTMVNYLTNTSVWIGGE
AFFGTLSPEQLEMIHQTGYEAGVYSQKLTLERDAEMLKTMQAAGVEVIYPDTGPFQKKAREVYSQFPEWTPGLYETIQQQ
LQ

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=285, Percent_Identity=31.2280701754386, Blast_Score=135, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 36232; Mature: 36101

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIAMLITVSTLFLPSIIQAKPISIKVAYENNPGEPLDVVMRYWADLLNKKSNGEITL
CHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEE
ALYPSSQLGSKQDVTEQAIMGMNVITLSDVAFLADYEPDLGILFGPYLTDDPQKLFKIYE
EECCCHHCCCHHHHHHHHHHCCCEEEHHHHHHEECCCCCCCEEECCCCCCCHHHHHHHHH
SDWFKQKNESLKKKGIHVVMNNYLYGTRQIISKKPIRTVDDLAGLKIRVPNNVMQIKAIQ
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCHHHHHCCCEEECCCCCEEEHHHH
AMGATPTPMPLGEVYPALTQGVIDGVENPISVLQGQKLYEQARYLTMVNYLTNTSVWIGG
HCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECC
EAFFGTLSPEQLEMIHQTGYEAGVYSQKLTLERDAEMLKTMQAAGVEVIYPDTGPFQKKA
HHEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHH
REVYSQFPEWTPGLYETIQQQLQ
HHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SKIIAMLITVSTLFLPSIIQAKPISIKVAYENNPGEPLDVVMRYWADLLNKKSNGEITL
HHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCEEE
ALYPSSQLGSKQDVTEQAIMGMNVITLSDVAFLADYEPDLGILFGPYLTDDPQKLFKIYE
EECCCHHCCCHHHHHHHHHHCCCEEEHHHHHHEECCCCCCCEEECCCCCCCHHHHHHHHH
SDWFKQKNESLKKKGIHVVMNNYLYGTRQIISKKPIRTVDDLAGLKIRVPNNVMQIKAIQ
HHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCHHHHHCCCEEECCCCCEEEHHHH
AMGATPTPMPLGEVYPALTQGVIDGVENPISVLQGQKLYEQARYLTMVNYLTNTSVWIGG
HCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCEEECC
EAFFGTLSPEQLEMIHQTGYEAGVYSQKLTLERDAEMLKTMQAAGVEVIYPDTGPFQKKA
HHEECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHH
REVYSQFPEWTPGLYETIQQQLQ
HHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA