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The map label for this gene is fimA [H]

Identifier: 218692719

GI number: 218692719

Start: 5129391

End: 5129939

Strand: Direct

Name: fimA [H]

Synonym: ECED1_5199

Alternate gene names: 218692719

Gene position: 5129391-5129939 (Clockwise)

Preceding gene: 218692718

Following gene: 218692720

Centisome position: 98.46

GC content: 50.46

Gene sequence:

>549_bases
ATGAAAATTAAAACTCTGGCAATCGTTGTTCTGTCGGCTCTGTCCCTCAGTTCCACAGCGGCTCTGGCCGCTGCCACGAC
GGTTAATGGTGGGACCGTTCACTTTAAAGGGGAAGTTGTTAACGCCGCTTGCGCAGTTGATGCAGGCTCTGTTGATCAAA
CCGTTCAGTTAGGGCAGGTTCGTACCGCATCGCTGGCACAAGAAGGAGCAACCAGTTCTGCTGTCGGTTTTAACATTCAA
CTGAACGATTGTGACACTACTGTTGCAGACAAAGCAGCTATTGCCTTCCTTGGTACCGCAATTGATGGAAATCATCCTAA
CGTATTGGCTCTGCAGAGTTCTGCTGCAGGTAGCGCAACAAGCGTTGGTGTGCAAATTCTGGACAGAACAGGCAATGCTC
TGACGCTGGACGGTGCGACATTTAGTGCACAAACAACCCTGAATAACGGTACCAACACCATTCCGTTCCAGGCGCGTTAT
TATGCAATCGGCGAGGCAACCCCGGGTGCAGCTAATGCGGATGCGACCTTCAAGGTTCAGTATCAATAA

Upstream 100 bases:

>100_bases
AAAACTGTGCAGTGTTGGCAGTCAAACTCGTTGACAAAACAAAGTGTACAGAACGACTGCCCATGTCGATTTAGAAATAG
TTTTTTTAAAGGAAAGCAGC

Downstream 100 bases:

>100_bases
CCTACCCAGGTTCAGGGACGTCATTACGGGCAGGGATGCCCACCCTTGTGCGATAAAAATAACGATGAAAAGGAAGAGAT
TATTTCTGTTAGCGTCGTTG

Product: major type 1 subunit fimbrin

Products: NA

Alternate protein names: Type-1A pilin [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MKIKTLAIVVLSALSLSSTAALAAATTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLAQEGATSSAVGFNIQ
LNDCDTTVADKAAIAFLGTAIDGNHPNVLALQSSAAGSATSVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARY
YAIGEATPGAANADATFKVQYQ

Sequences:

>Translated_182_residues
MKIKTLAIVVLSALSLSSTAALAAATTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLAQEGATSSAVGFNIQ
LNDCDTTVADKAAIAFLGTAIDGNHPNVLALQSSAAGSATSVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARY
YAIGEATPGAANADATFKVQYQ
>Mature_182_residues
MKIKTLAIVVLSALSLSSTAALAAATTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLAQEGATSSAVGFNIQ
LNDCDTTVADKAAIAFLGTAIDGNHPNVLALQSSAAGSATSVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARY
YAIGEATPGAANADATFKVQYQ

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

Organism=Escherichia coli, GI1790769, Length=182, Percent_Identity=92.8571428571429, Blast_Score=280, Evalue=3e-77,
Organism=Escherichia coli, GI87081753, Length=160, Percent_Identity=49.375, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI87082421, Length=183, Percent_Identity=33.879781420765, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1786938, Length=191, Percent_Identity=32.4607329842932, Blast_Score=73, Evalue=9e-15,
Organism=Escherichia coli, GI87081804, Length=183, Percent_Identity=32.7868852459016, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786746, Length=167, Percent_Identity=30.5389221556886, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1789422, Length=161, Percent_Identity=34.7826086956522, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1790773, Length=185, Percent_Identity=32.4324324324324, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 18264; Mature: 18264

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKTLAIVVLSALSLSSTAALAAATTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQV
CCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECEEEEEEEEECCCCCCCEEEECCE
RTASLAQEGATSSAVGFNIQLNDCDTTVADKAAIAFLGTAIDGNHPNVLALQSSAAGSAT
EEHHHHHCCCCCCEEEEEEEECCCCCCHHCCEEEEEEEEEECCCCCCEEEEECCCCCCCC
SVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARYYAIGEATPGAANADATFKVQ
EEEEEEEECCCCEEEECCCEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEE
YQ
EC
>Mature Secondary Structure
MKIKTLAIVVLSALSLSSTAALAAATTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQV
CCCHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECEEEEEEEEECCCCCCCEEEECCE
RTASLAQEGATSSAVGFNIQLNDCDTTVADKAAIAFLGTAIDGNHPNVLALQSSAAGSAT
EEHHHHHCCCCCCEEEEEEEECCCCCCHHCCEEEEEEEEEECCCCCCEEEEECCCCCCCC
SVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARYYAIGEATPGAANADATFKVQ
EEEEEEEECCCCEEEECCCEEEEEEEECCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEE
YQ
EC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8636962; 11251843; 12657207 [H]