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The map label for this gene is uhpA [H]

Identifier: 218692578

GI number: 218692578

Start: 4977733

End: 4978362

Strand: Reverse

Name: uhpA [H]

Synonym: ECED1_5045

Alternate gene names: 218692578

Gene position: 4978362-4977733 (Counterclockwise)

Preceding gene: 218692579

Following gene: 218692577

Centisome position: 95.56

GC content: 51.9

Gene sequence:

>630_bases
ATGATTCGGGTTGTGCTGGTGGATGACCATGTGGTGGTGCGCTCTGGTTTCGCACAGTTACTCTCTCTGGAAGACGATCT
GGAGGTCATTGGTCAGTACAGTAGTGCCGCACAGGCATGGTCGGCATTAATCTGTGATGACGTCAATGTTGCCGTCATTG
ATATTGCTATGCCGGACGAAAACGGCCTCAGTTTGGTTAAGCGCCTGCGTGCACAAAAACCGCAATTCCGCGCCATTATT
CTTAGCATTTATGACACGCCAACCTTTGTACAAAGCGCTCTGGATGCTGGTGCCAGTGGCTATTTGACCAAACGCTGTGG
GCCGGAAGAGTTAGTGCAGGCGGTGCGCTCTGTCGGTATGGGAGGGCATTATCTCTGCGCCGATGCAATTCGGGCTTTAC
GCGGCGGCGGGCAACCCGCCCAGGCACTGGAAATTCTCACCCCACGAGAACGTGAAGTGTTTGATTTATTAGTCAAAGGC
GACAGTGTAAAAGAGATTGCCTTTAAGCTCGAACTCAGCCATAAAACGGTACATGTACATCGCGCCAACGTGCTGGGAAA
ACTGAACTGTCATAGCACCATTGAGCTGGTGCATTTTGCACTCAACCACCATCTGCTGGCGGGGCATTAA

Upstream 100 bases:

>100_bases
TACATTTTTTGTTACATCCATTCCATATCTGTCGCTGGTTGATTGCCAGCGACGCGTCGTGATGCATGATAGGAGAATGA
GATAATAAGAGAAGAAAAGT

Downstream 100 bases:

>100_bases
TGTCGCGTAACCTTCGTCATTGGGTGATTTCGCTGTTTATTGTGCTGGCCTGGGGAAGCGGCTGGCTGATGTTGTGGACG
CTCAGCTTTTATCTGACCAA

Product: putative response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIRVVLVDDHVVVRSGFAQLLSLEDDLEVIGQYSSAAQAWSALICDDVNVAVIDIAMPDENGLSLVKRLRAQKPQFRAII
LSIYDTPTFVQSALDAGASGYLTKRCGPEELVQAVRSVGMGGHYLCADAIRALRGGGQPAQALEILTPREREVFDLLVKG
DSVKEIAFKLELSHKTVHVHRANVLGKLNCHSTIELVHFALNHHLLAGH

Sequences:

>Translated_209_residues
MIRVVLVDDHVVVRSGFAQLLSLEDDLEVIGQYSSAAQAWSALICDDVNVAVIDIAMPDENGLSLVKRLRAQKPQFRAII
LSIYDTPTFVQSALDAGASGYLTKRCGPEELVQAVRSVGMGGHYLCADAIRALRGGGQPAQALEILTPREREVFDLLVKG
DSVKEIAFKLELSHKTVHVHRANVLGKLNCHSTIELVHFALNHHLLAGH
>Mature_209_residues
MIRVVLVDDHVVVRSGFAQLLSLEDDLEVIGQYSSAAQAWSALICDDVNVAVIDIAMPDENGLSLVKRLRAQKPQFRAII
LSIYDTPTFVQSALDAGASGYLTKRCGPEELVQAVRSVGMGGHYLCADAIRALRGGGQPAQALEILTPREREVFDLLVKG
DSVKEIAFKLELSHKTVHVHRANVLGKLNCHSTIELVHFALNHHLLAGH

Specific function: Appears to be the positive activator of uhpT transcription [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=197, Percent_Identity=48.7309644670051, Blast_Score=173, Evalue=9e-45,
Organism=Escherichia coli, GI1788222, Length=209, Percent_Identity=32.5358851674641, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=34.8717948717949, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1786747, Length=205, Percent_Identity=26.8292682926829, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=32.6086956521739, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788546, Length=201, Percent_Identity=25.8706467661692, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788712, Length=199, Percent_Identity=24.6231155778894, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22793; Mature: 22793

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVVLVDDHVVVRSGFAQLLSLEDDLEVIGQYSSAAQAWSALICDDVNVAVIDIAMPDE
CEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
NGLSLVKRLRAQKPQFRAIILSIYDTPTFVQSALDAGASGYLTKRCGPEELVQAVRSVGM
CHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHCCC
GGHYLCADAIRALRGGGQPAQALEILTPREREVFDLLVKGDSVKEIAFKLELSHKTVHVH
CCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHCCCCHHEEEEEEEECCCEEEEE
RANVLGKLNCHSTIELVHFALNHHLLAGH
ECCCEEECCCHHHHHHHHHHHHCEEECCC
>Mature Secondary Structure
MIRVVLVDDHVVVRSGFAQLLSLEDDLEVIGQYSSAAQAWSALICDDVNVAVIDIAMPDE
CEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
NGLSLVKRLRAQKPQFRAIILSIYDTPTFVQSALDAGASGYLTKRCGPEELVQAVRSVGM
CHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCEECCCCHHHHHHHHHHCCC
GGHYLCADAIRALRGGGQPAQALEILTPREREVFDLLVKGDSVKEIAFKLELSHKTVHVH
CCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHCCCCHHEEEEEEEECCCEEEEE
RANVLGKLNCHSTIELVHFALNHHLLAGH
ECCCEEECCCHHHHHHHHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]