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The map label for this gene is uhpC [H]

Identifier: 218692576

GI number: 218692576

Start: 4974803

End: 4976119

Strand: Reverse

Name: uhpC [H]

Synonym: ECED1_5043

Alternate gene names: 218692576

Gene position: 4976119-4974803 (Counterclockwise)

Preceding gene: 218692577

Following gene: 218692575

Centisome position: 95.52

GC content: 54.06

Gene sequence:

>1317_bases
ATGGAGACGACCATGCACGCGCGTTCAGCGAGAGAGATTAATCAATGCTACCGGACATTACGTCCACGATTGCTGATGTG
CATGATTATTGGCTACGCCGCATTTTATCTGACGCGAAAAAGCGTGAATTACGTCCTTCCGGCGCTGCAAACCGACCTCG
GACTGGATAAAGGCGACATTGGCCTGCTGGGTTCACTGTTTTATCTCAGCTACGGATTGTCGAAATTTACCGCCGGACTG
TGGCATGACAGCCACGGACAACGCGGTTTTATGGGTATCGGCTTGTTCGCCACTGGGCTATTGAACGTGGTGTTTGCCTT
TGGCGAATCACTTACGCTTCTGCTTGTGGTCTGGACACTGAACGGATTTTTTCAAGGCTGGGGGTGGCCACCGTGTGCCC
GCTTACTGACCCATTGGTATTCCCGTAATGAACGTGGTTTCTGGTGGGGCTGCTGGAATATGTCGATCAACATTGGCGGA
GCGATTATTCCGCTGATTAGCGCCTTTGCCGCCCACTGGTGGGGCTGGCAGGCCGCGATGCTGACACCGGGGATAATCAG
CATGGCATTAGGGATCTGGTTAACGCTACAACTCAAAAGCACGCCCCAGGAAGAGGGATTACCGACAGTTGGTCACTGGC
GTCACGATCCGCTGGAGTTACGTCAGGAACAACAAAGTCCGCCGATGGGGCTGTGGCAAATGTTGCGCACCACCATGCTG
CAAAATCCGCTGATCTGGCTACTGGGTGTCTCTTATGTACTTGTTTATGTGATCCGGATTGCGCTAAACGACTGGGGCAA
TATCTGGCTGACGGAAAGCCACGGCGTCAACCTGCTCAGCGCCAACGCCACGGTAATGCTGTTTGAAGTAGGCGGCTTAC
TCGGGGCGTTATTTGCCGGATGGGGTTCGGATTTGCTGTTTAGCGGGCAGCGAGCCCCCATGATTTTGCTGTTTACCCTT
GGGTTGATGGTTTCGGTCGCTGCACTCTGGTTGGCACCGGTTCATCACTATGCCCTTCTGGCTGTGTGCTTTTTTACTGT
GGGCTTTTTTGTCTTTGGCCCGCAAATGCTGATTGGACTTGCGGCAGTGGAATGTGGACACAAAGCTGCGGCGGGTTCAA
TCACCGGATTTCTCGGCCTGTTCGCCTATCTCGGTGCGGCGCTGGCAGGCTGGCCGTTGTCGCTGGTTATCGAACGCTAC
GGCTGGTCGGGAATGTTCAGTTTACTCTCGGTCGCCGCAGTACTTATGGGTTTACTGCTGATGCCGTTACTGATGGCGGG
CATCACCACCACTCACGCTCGAAGGATAAAACAATGA

Upstream 100 bases:

>100_bases
CACATTTTTGCAACAAATCGCCGGATAACCAGGAAAAAGTCTTAGTCATCCCGGATTTTCTCTCATCCTCTTTCACTTTC
ATTTTCATATAGTCAGCAAC

Downstream 100 bases:

>100_bases
AAATGCCCCTTACCTCTACTCTGATTGCTTCTGCCGTTGCGCTAGCAACCTTAACGGGTGCCGCGCAGGCAAAAGGCCGG
CTGGTGGTCTATTGCAGCGC

Product: putative regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
METTMHARSAREINQCYRTLRPRLLMCMIIGYAAFYLTRKSVNYVLPALQTDLGLDKGDIGLLGSLFYLSYGLSKFTAGL
WHDSHGQRGFMGIGLFATGLLNVVFAFGESLTLLLVVWTLNGFFQGWGWPPCARLLTHWYSRNERGFWWGCWNMSINIGG
AIIPLISAFAAHWWGWQAAMLTPGIISMALGIWLTLQLKSTPQEEGLPTVGHWRHDPLELRQEQQSPPMGLWQMLRTTML
QNPLIWLLGVSYVLVYVIRIALNDWGNIWLTESHGVNLLSANATVMLFEVGGLLGALFAGWGSDLLFSGQRAPMILLFTL
GLMVSVAALWLAPVHHYALLAVCFFTVGFFVFGPQMLIGLAAVECGHKAAAGSITGFLGLFAYLGAALAGWPLSLVIERY
GWSGMFSLLSVAAVLMGLLLMPLLMAGITTTHARRIKQ

Sequences:

>Translated_438_residues
METTMHARSAREINQCYRTLRPRLLMCMIIGYAAFYLTRKSVNYVLPALQTDLGLDKGDIGLLGSLFYLSYGLSKFTAGL
WHDSHGQRGFMGIGLFATGLLNVVFAFGESLTLLLVVWTLNGFFQGWGWPPCARLLTHWYSRNERGFWWGCWNMSINIGG
AIIPLISAFAAHWWGWQAAMLTPGIISMALGIWLTLQLKSTPQEEGLPTVGHWRHDPLELRQEQQSPPMGLWQMLRTTML
QNPLIWLLGVSYVLVYVIRIALNDWGNIWLTESHGVNLLSANATVMLFEVGGLLGALFAGWGSDLLFSGQRAPMILLFTL
GLMVSVAALWLAPVHHYALLAVCFFTVGFFVFGPQMLIGLAAVECGHKAAAGSITGFLGLFAYLGAALAGWPLSLVIERY
GWSGMFSLLSVAAVLMGLLLMPLLMAGITTTHARRIKQ
>Mature_438_residues
METTMHARSAREINQCYRTLRPRLLMCMIIGYAAFYLTRKSVNYVLPALQTDLGLDKGDIGLLGSLFYLSYGLSKFTAGL
WHDSHGQRGFMGIGLFATGLLNVVFAFGESLTLLLVVWTLNGFFQGWGWPPCARLLTHWYSRNERGFWWGCWNMSINIGG
AIIPLISAFAAHWWGWQAAMLTPGIISMALGIWLTLQLKSTPQEEGLPTVGHWRHDPLELRQEQQSPPMGLWQMLRTTML
QNPLIWLLGVSYVLVYVIRIALNDWGNIWLTESHGVNLLSANATVMLFEVGGLLGALFAGWGSDLLFSGQRAPMILLFTL
GLMVSVAALWLAPVHHYALLAVCFFTVGFFVFGPQMLIGLAAVECGHKAAAGSITGFLGLFAYLGAALAGWPLSLVIERY
GWSGMFSLLSVAAVLMGLLLMPLLMAGITTTHARRIKQ

Specific function: UhpC is required for uhpT expression, it may act jointly with the uhpB signaling protein [H]

COG id: COG2271

COG function: function code G; Sugar phosphate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family [H]

Homologues:

Organism=Homo sapiens, GI256219598, Length=405, Percent_Identity=28.3950617283951, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI4503847, Length=405, Percent_Identity=28.3950617283951, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI256219483, Length=405, Percent_Identity=28.3950617283951, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI256219543, Length=424, Percent_Identity=27.5943396226415, Blast_Score=185, Evalue=8e-47,
Organism=Homo sapiens, GI256219564, Length=326, Percent_Identity=27.6073619631902, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI46361976, Length=411, Percent_Identity=23.1143552311436, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI223717983, Length=481, Percent_Identity=22.2453222453222, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI38093649, Length=481, Percent_Identity=22.2453222453222, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI49619231, Length=349, Percent_Identity=24.0687679083095, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082310, Length=415, Percent_Identity=53.7349397590362, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1788573, Length=435, Percent_Identity=31.264367816092, Blast_Score=244, Evalue=5e-66,
Organism=Escherichia coli, GI2367259, Length=432, Percent_Identity=29.1666666666667, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI2367379, Length=384, Percent_Identity=24.4791666666667, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17561094, Length=400, Percent_Identity=23.5, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17542316, Length=465, Percent_Identity=23.8709677419355, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI133901854, Length=435, Percent_Identity=24.367816091954, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI133901856, Length=435, Percent_Identity=24.367816091954, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI133930953, Length=407, Percent_Identity=23.5872235872236, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17539138, Length=322, Percent_Identity=22.0496894409938, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24656861, Length=485, Percent_Identity=25.7731958762887, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24656866, Length=485, Percent_Identity=25.7731958762887, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI45550478, Length=485, Percent_Identity=25.7731958762887, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000849
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR021159 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48418; Mature: 48418

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METTMHARSAREINQCYRTLRPRLLMCMIIGYAAFYLTRKSVNYVLPALQTDLGLDKGDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GLLGSLFYLSYGLSKFTAGLWHDSHGQRGFMGIGLFATGLLNVVFAFGESLTLLLVVWTL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
NGFFQGWGWPPCARLLTHWYSRNERGFWWGCWNMSINIGGAIIPLISAFAAHWWGWQAAM
HHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHCCCHHHH
LTPGIISMALGIWLTLQLKSTPQEEGLPTVGHWRHDPLELRQEQQSPPMGLWQMLRTTML
HCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
QNPLIWLLGVSYVLVYVIRIALNDWGNIWLTESHGVNLLSANATVMLFEVGGLLGALFAG
HCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCEEEEEHHHHHHHHHHHC
WGSDLLFSGQRAPMILLFTLGLMVSVAALWLAPVHHYALLAVCFFTVGFFVFGPQMLIGL
CCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVECGHKAAAGSITGFLGLFAYLGAALAGWPLSLVIERYGWSGMFSLLSVAAVLMGLLL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
MPLLMAGITTTHARRIKQ
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
METTMHARSAREINQCYRTLRPRLLMCMIIGYAAFYLTRKSVNYVLPALQTDLGLDKGDI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
GLLGSLFYLSYGLSKFTAGLWHDSHGQRGFMGIGLFATGLLNVVFAFGESLTLLLVVWTL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
NGFFQGWGWPPCARLLTHWYSRNERGFWWGCWNMSINIGGAIIPLISAFAAHWWGWQAAM
HHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHCCCHHHH
LTPGIISMALGIWLTLQLKSTPQEEGLPTVGHWRHDPLELRQEQQSPPMGLWQMLRTTML
HCHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHH
QNPLIWLLGVSYVLVYVIRIALNDWGNIWLTESHGVNLLSANATVMLFEVGGLLGALFAG
HCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCEEEEEHHHHHHHHHHHC
WGSDLLFSGQRAPMILLFTLGLMVSVAALWLAPVHHYALLAVCFFTVGFFVFGPQMLIGL
CCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAVECGHKAAAGSITGFLGLFAYLGAALAGWPLSLVIERYGWSGMFSLLSVAAVLMGLLL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
MPLLMAGITTTHARRIKQ
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1569007; 11677609 [H]