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The map label for this gene is dppB [H]

Identifier: 218692374

GI number: 218692374

Start: 4771522

End: 4772664

Strand: Reverse

Name: dppB [H]

Synonym: ECED1_4810

Alternate gene names: 218692374

Gene position: 4772664-4771522 (Counterclockwise)

Preceding gene: 218692375

Following gene: 218692373

Centisome position: 91.61

GC content: 54.42

Gene sequence:

>1143_bases
ATGCAACTCGCGTCCAGCCCTGTTACCGGGCGCGGTACCAGGGCTGGCCTGTATTGCAGGCCAGCCGCTGATTTATCACT
GTATGGAAAGATCATGTCTGTCGTTTTTTCCACTCGCGCGAGATGGCGAGGCAAGCGCCCTCTGCTCGCGCTGTTGCAAG
GGCTGTTTACCGTTGCTCTGACGCTACTCGGCCTGCTGCTGATTACCTTTGCGCTTTCGGCTCTCTCACCGGTCGATCGC
GTACTACAAATCGTTGGCGATCACGCCAGCCAGTCCACCTATGATCAGGTACGCCACCAGTTAGGATTGGATCAGCCGTT
AGCCGTCCAGTTCTGGCATTACCTGATGAATCTGGCACACGGCGATCTGGGCATCGCCAGCTCCACCGGGCAACCGGTAC
TCCAGGACTTGCTATCAGTATTCCCGGCGACCATTGAACTGGCAACGTTGGCGCTTATTGTCGGTGCTGTTGTCGGCGTC
ATTGCGGGTGTACTTTGCGCCCGTTATGTCGGTTCTCCGCTGGATTTCACCGTGCGAACATTAACTCTACTGGGAAATTC
CGTCCCTGTTTTTTGGCTTGGTCTGCTGATGCTGGCGCTGTTCTACGCCAGACTGCAATGGAGTGCCGGGCCGGGCAGGC
TGGATGATATTTATCAATTCACCATAGAACCCCGCAGCGGATTTGCGCTGATTGATACGTGGCTTTCTGGCGATCGCGAG
GCATTTACCAATGCAATCAACCATTTGATACTTCCGGTTTTATTACTGGCGTACTTCTCGCTCGCCAGTATTACGCGCCT
GACTCGTTCCGCCTGTCTTGGCGAAATGAATAAAGAATATATTCTGCTGGCGCGCGCCAAAGGGGCCAGCGAGATGACAA
TTTTGCTACGTCATGTTTTACCCAACATTCGCGGCACCTTGCTCACCGTTATCGCCCTCGCCTATACATCAATGCTGGAA
GGCGCGGTACTGACAGAAACCGTCTTTTCATGGCCAGGTATTGGGCGCTACCTCACTACAGCGCTCTTCGCGGGTGATAC
CACAGCAATCATGGGAGGAACGCTGCTGATTGGCGTCTGCTTTGTGTTGATAAATAACTTAACCGACCTGCTGGTCCGGC
TGACCGATCCGAGGTTACGCTGA

Upstream 100 bases:

>100_bases
AGGCAAAACGCAAATTGTCATGCGTGATAATGTGCAGGGGTATCAACAAGGGTTGAATGCCGATATGGTCTGGTTTGATC
AGGTAACCAAATAACCCTGT

Downstream 100 bases:

>100_bases
TGCCGATGTTTCTCTTTTTACGCCGTTTACGCCATTCACCCGCCGCGTTTTGCGGGTTGATAATTATCCTGTTATTGATG
CTAATTGCGCTCTTCGCGCC

Product: putative dipeptide/nickel transporter, Inner membrane permease subunit (yddR)

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MQLASSPVTGRGTRAGLYCRPAADLSLYGKIMSVVFSTRARWRGKRPLLALLQGLFTVALTLLGLLLITFALSALSPVDR
VLQIVGDHASQSTYDQVRHQLGLDQPLAVQFWHYLMNLAHGDLGIASSTGQPVLQDLLSVFPATIELATLALIVGAVVGV
IAGVLCARYVGSPLDFTVRTLTLLGNSVPVFWLGLLMLALFYARLQWSAGPGRLDDIYQFTIEPRSGFALIDTWLSGDRE
AFTNAINHLILPVLLLAYFSLASITRLTRSACLGEMNKEYILLARAKGASEMTILLRHVLPNIRGTLLTVIALAYTSMLE
GAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVCFVLINNLTDLLVRLTDPRLR

Sequences:

>Translated_380_residues
MQLASSPVTGRGTRAGLYCRPAADLSLYGKIMSVVFSTRARWRGKRPLLALLQGLFTVALTLLGLLLITFALSALSPVDR
VLQIVGDHASQSTYDQVRHQLGLDQPLAVQFWHYLMNLAHGDLGIASSTGQPVLQDLLSVFPATIELATLALIVGAVVGV
IAGVLCARYVGSPLDFTVRTLTLLGNSVPVFWLGLLMLALFYARLQWSAGPGRLDDIYQFTIEPRSGFALIDTWLSGDRE
AFTNAINHLILPVLLLAYFSLASITRLTRSACLGEMNKEYILLARAKGASEMTILLRHVLPNIRGTLLTVIALAYTSMLE
GAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVCFVLINNLTDLLVRLTDPRLR
>Mature_380_residues
MQLASSPVTGRGTRAGLYCRPAADLSLYGKIMSVVFSTRARWRGKRPLLALLQGLFTVALTLLGLLLITFALSALSPVDR
VLQIVGDHASQSTYDQVRHQLGLDQPLAVQFWHYLMNLAHGDLGIASSTGQPVLQDLLSVFPATIELATLALIVGAVVGV
IAGVLCARYVGSPLDFTVRTLTLLGNSVPVFWLGLLMLALFYARLQWSAGPGRLDDIYQFTIEPRSGFALIDTWLSGDRE
AFTNAINHLILPVLLLAYFSLASITRLTRSACLGEMNKEYILLARAKGASEMTILLRHVLPNIRGTLLTVIALAYTSMLE
GAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVCFVLINNLTDLLVRLTDPRLR

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=334, Percent_Identity=39.2215568862275, Blast_Score=228, Evalue=4e-61,
Organism=Escherichia coli, GI1787761, Length=332, Percent_Identity=43.6746987951807, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1787550, Length=274, Percent_Identity=38.6861313868613, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1789888, Length=283, Percent_Identity=34.2756183745583, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1787053, Length=335, Percent_Identity=30.7462686567164, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787497, Length=322, Percent_Identity=27.639751552795, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788504, Length=293, Percent_Identity=27.3037542662116, Blast_Score=99, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 41243; Mature: 41243

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLASSPVTGRGTRAGLYCRPAADLSLYGKIMSVVFSTRARWRGKRPLLALLQGLFTVAL
CCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TLLGLLLITFALSALSPVDRVLQIVGDHASQSTYDQVRHQLGLDQPLAVQFWHYLMNLAH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
GDLGIASSTGQPVLQDLLSVFPATIELATLALIVGAVVGVIAGVLCARYVGSPLDFTVRT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LTLLGNSVPVFWLGLLMLALFYARLQWSAGPGRLDDIYQFTIEPRSGFALIDTWLSGDRE
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEECCCCCCCHHHHHHCCCHH
AFTNAINHLILPVLLLAYFSLASITRLTRSACLGEMNKEYILLARAKGASEMTILLRHVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
PNIRGTLLTVIALAYTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVC
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
FVLINNLTDLLVRLTDPRLR
HHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQLASSPVTGRGTRAGLYCRPAADLSLYGKIMSVVFSTRARWRGKRPLLALLQGLFTVAL
CCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
TLLGLLLITFALSALSPVDRVLQIVGDHASQSTYDQVRHQLGLDQPLAVQFWHYLMNLAH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHC
GDLGIASSTGQPVLQDLLSVFPATIELATLALIVGAVVGVIAGVLCARYVGSPLDFTVRT
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LTLLGNSVPVFWLGLLMLALFYARLQWSAGPGRLDDIYQFTIEPRSGFALIDTWLSGDRE
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEEEECCCCCCCHHHHHHCCCHH
AFTNAINHLILPVLLLAYFSLASITRLTRSACLGEMNKEYILLARAKGASEMTILLRHVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
PNIRGTLLTVIALAYTSMLEGAVLTETVFSWPGIGRYLTTALFAGDTTAIMGGTLLIGVC
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
FVLINNLTDLLVRLTDPRLR
HHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]