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The map label for this gene is eutE [H]

Identifier: 218691116

GI number: 218691116

Start: 3397930

End: 3399456

Strand: Direct

Name: eutE [H]

Synonym: ECED1_3458

Alternate gene names: 218691116

Gene position: 3397930-3399456 (Clockwise)

Preceding gene: 218691115

Following gene: 218691117

Centisome position: 65.23

GC content: 53.63

Gene sequence:

>1527_bases
ATGAATGATATTGAAATCGCTCAGGCTGTCTCGACCATCCTGAGCAAATTCACCAAAGCAACACCGGATGAAGCTCCCGC
CACGTCAGAAGCAGCGCGGGTCGACGGGTTGGATGAAATTGTCGCTAAGGCGTTGGCGCAGCACTCTTCCGTGCGCGACG
CCAGTGCGATCTCTCAGGTAGCGAAGGTAGCGAAGGTAGCGAATGCTAGCACTGGAGCATTCGATACCATGGATGAGGCG
ATTTCCGCCGCCGTCTTGGCACAGGTACAGTATCGCCACTGTTCTATGCAAGACCGCGCCTCGTTTATCAATGGCATTCG
CGATGTCTTCCTGCAGGAAGATGTGCTGTGTGCCCTTTCCCGTATGGCGGTGGAAGAGACCGGCATGGGGAATTACGAGG
ACAAACTGATCAAAAACCGCGTCGCAGCGCTGAAAACGCCAGGTATCGAAGATCTGACCACCAGCGCGGTTTCCGGAGAC
GGGGGTTTAACGTTGATCGAATACTCTGCGTTCGGAGTGATTGGTTCGATTACACCAACGACTAACCCGACCGAAACCAT
TATCAACAACAGCATAGGCATGCTGGCGGCAGGCAACACTGTGGTGTTCAGTCCACATCCGCGCTCGCGCAAAGTGTCGC
TGTACGCGGTTGAGCTGATCAACAACAAGCTTGCCCAGTTGGGCGCACCGGCGAACATGGTGGTAACGGTGACCAAACCG
TCCATCGACAATACCAACGTCCTGATCAACGACCCACGTATCAACATGCTGGTAGCGACTGGCGGTCCAGCCATCGTGAA
AACCGTGATGTCATCAGGTAAAAAAGCGATTGGTGCAGGCGCAGGTAACCCGCCAGCTGTGGTAGATGAAACGGCGGATA
TCGAAAAAGCAGCCCGCGACATCATTAAGGGCTGTAGCTTCGACAACAACCTGCCGTGCGTGGCGGAAAAAGAGGTGATT
GTTGTGAACCAGGTAGCGGACTATCTGATTCACTGCATGAAGAAAAGCGGTGCCTATCTGTTGTGCGATAAGAAGTTAAG
TCAACAACTGCAATCGTTGGTGCTTAATGAAAAAGGCACTGGGCCGAATACCGCCTTTGTCGGCAAAGATGCGCGCTATA
TCCTGCAACAACTGGGAATCCAGGTTGGCGACGATATCAAAGTCATCTTAATTGAGGCTGAGAAAACACATCCGTTTGTG
GTGCATGAGCTGATGATGCCGGTCCTGCCGGTGGTGCGCGTAGACAATGTTGATGAAGCCATTGAGCTGGCGGTGAAAGT
GGAGCACGGCAATCGTCATACCGCGGTTATGCACTCCACCAACGTCGAAAAGCTGACCAAAATGGCGCGCCTGATCCAGA
CCACCATCTTTGTTAAAAATGGTCCCTCTTATGCAGGGCTGGGGGTGGGCGGTGAAGGGCATGCCACCTTTACGATTGCC
GGACCGACCGGCGAGGGACTTACGTCAGCGCGTTCGTTTGCACGCCGTCGTCGCTGTGTAATGGTTGAAGCGCTGAATAT
TCGCTAA

Upstream 100 bases:

>100_bases
TCCGGTGGAAATTAAATCCACCACGACGCCATATATCTAAGCATCTGATGACGATGCACGCGGCGCGGTCGGTAGATGAA
GAGTAGTAAGGAATTTAAAG

Downstream 100 bases:

>100_bases
CTATCGCGAAGGGTGACTTAAAGATGAAAAAACGAATCATAAACGCACCGACCCCGGATATTTTGGCTATGTTGAAACGG
CGTATGCCCGGGGAGTTTCG

Product: putative acetaldehyde/propionaldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MNDIEIAQAVSTILSKFTKATPDEAPATSEAARVDGLDEIVAKALAQHSSVRDASAISQVAKVAKVANASTGAFDTMDEA
ISAAVLAQVQYRHCSMQDRASFINGIRDVFLQEDVLCALSRMAVEETGMGNYEDKLIKNRVAALKTPGIEDLTTSAVSGD
GGLTLIEYSAFGVIGSITPTTNPTETIINNSIGMLAAGNTVVFSPHPRSRKVSLYAVELINNKLAQLGAPANMVVTVTKP
SIDNTNVLINDPRINMLVATGGPAIVKTVMSSGKKAIGAGAGNPPAVVDETADIEKAARDIIKGCSFDNNLPCVAEKEVI
VVNQVADYLIHCMKKSGAYLLCDKKLSQQLQSLVLNEKGTGPNTAFVGKDARYILQQLGIQVGDDIKVILIEAEKTHPFV
VHELMMPVLPVVRVDNVDEAIELAVKVEHGNRHTAVMHSTNVEKLTKMARLIQTTIFVKNGPSYAGLGVGGEGHATFTIA
GPTGEGLTSARSFARRRRCVMVEALNIR

Sequences:

>Translated_508_residues
MNDIEIAQAVSTILSKFTKATPDEAPATSEAARVDGLDEIVAKALAQHSSVRDASAISQVAKVAKVANASTGAFDTMDEA
ISAAVLAQVQYRHCSMQDRASFINGIRDVFLQEDVLCALSRMAVEETGMGNYEDKLIKNRVAALKTPGIEDLTTSAVSGD
GGLTLIEYSAFGVIGSITPTTNPTETIINNSIGMLAAGNTVVFSPHPRSRKVSLYAVELINNKLAQLGAPANMVVTVTKP
SIDNTNVLINDPRINMLVATGGPAIVKTVMSSGKKAIGAGAGNPPAVVDETADIEKAARDIIKGCSFDNNLPCVAEKEVI
VVNQVADYLIHCMKKSGAYLLCDKKLSQQLQSLVLNEKGTGPNTAFVGKDARYILQQLGIQVGDDIKVILIEAEKTHPFV
VHELMMPVLPVVRVDNVDEAIELAVKVEHGNRHTAVMHSTNVEKLTKMARLIQTTIFVKNGPSYAGLGVGGEGHATFTIA
GPTGEGLTSARSFARRRRCVMVEALNIR
>Mature_508_residues
MNDIEIAQAVSTILSKFTKATPDEAPATSEAARVDGLDEIVAKALAQHSSVRDASAISQVAKVAKVANASTGAFDTMDEA
ISAAVLAQVQYRHCSMQDRASFINGIRDVFLQEDVLCALSRMAVEETGMGNYEDKLIKNRVAALKTPGIEDLTTSAVSGD
GGLTLIEYSAFGVIGSITPTTNPTETIINNSIGMLAAGNTVVFSPHPRSRKVSLYAVELINNKLAQLGAPANMVVTVTKP
SIDNTNVLINDPRINMLVATGGPAIVKTVMSSGKKAIGAGAGNPPAVVDETADIEKAARDIIKGCSFDNNLPCVAEKEVI
VVNQVADYLIHCMKKSGAYLLCDKKLSQQLQSLVLNEKGTGPNTAFVGKDARYILQQLGIQVGDDIKVILIEAEKTHPFV
VHELMMPVLPVVRVDNVDEAIELAVKVEHGNRHTAVMHSTNVEKLTKMARLIQTTIFVKNGPSYAGLGVGGEGHATFTIA
GPTGEGLTSARSFARRRRCVMVEALNIR

Specific function: May act as an acetaldehyde dehydrogenase that converts acetaldehyde into acetyl-CoA [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4502043, Length=465, Percent_Identity=22.7956989247312, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI238814371, Length=465, Percent_Identity=22.7956989247312, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI73695881, Length=356, Percent_Identity=23.314606741573, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI73695879, Length=356, Percent_Identity=23.314606741573, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI71773324, Length=372, Percent_Identity=23.6559139784946, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788797, Length=394, Percent_Identity=51.2690355329949, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1787493, Length=365, Percent_Identity=35.0684931506849, Blast_Score=190, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI25146394, Length=446, Percent_Identity=25.7847533632287, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI32566756, Length=446, Percent_Identity=25.7847533632287, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI25146391, Length=466, Percent_Identity=25.3218884120172, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17564084, Length=266, Percent_Identity=25.187969924812, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24666674, Length=286, Percent_Identity=24.4755244755245, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012408
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: NA

Molecular weight: Translated: 54014; Mature: 54014

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDIEIAQAVSTILSKFTKATPDEAPATSEAARVDGLDEIVAKALAQHSSVRDASAISQV
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
AKVAKVANASTGAFDTMDEAISAAVLAQVQYRHCSMQDRASFINGIRDVFLQEDVLCALS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RMAVEETGMGNYEDKLIKNRVAALKTPGIEDLTTSAVSGDGGLTLIEYSAFGVIGSITPT
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEEECCEEEECCCC
TNPTETIINNSIGMLAAGNTVVFSPHPRSRKVSLYAVELINNKLAQLGAPANMVVTVTKP
CCCHHHHHCCCCCEEEECCEEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEEECC
SIDNTNVLINDPRINMLVATGGPAIVKTVMSSGKKAIGAGAGNPPAVVDETADIEKAARD
CCCCCEEEEECCCEEEEEECCCHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHH
IIKGCSFDNNLPCVAEKEVIVVNQVADYLIHCMKKSGAYLLCDKKLSQQLQSLVLNEKGT
HHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCC
GPNTAFVGKDARYILQQLGIQVGDDIKVILIEAEKTHPFVVHELMMPVLPVVRVDNVDEA
CCCCEEECCHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEECCHHHE
IELAVKVEHGNRHTAVMHSTNVEKLTKMARLIQTTIFVKNGPSYAGLGVGGEGHATFTIA
EEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHEEEECCCCEECCCCCCCCCEEEEEE
GPTGEGLTSARSFARRRRCVMVEALNIR
CCCCCCHHHHHHHHHHHHEEEEEEECCC
>Mature Secondary Structure
MNDIEIAQAVSTILSKFTKATPDEAPATSEAARVDGLDEIVAKALAQHSSVRDASAISQV
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHH
AKVAKVANASTGAFDTMDEAISAAVLAQVQYRHCSMQDRASFINGIRDVFLQEDVLCALS
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RMAVEETGMGNYEDKLIKNRVAALKTPGIEDLTTSAVSGDGGLTLIEYSAFGVIGSITPT
HHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEEEEECCEEEECCCC
TNPTETIINNSIGMLAAGNTVVFSPHPRSRKVSLYAVELINNKLAQLGAPANMVVTVTKP
CCCHHHHHCCCCCEEEECCEEEECCCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEEECC
SIDNTNVLINDPRINMLVATGGPAIVKTVMSSGKKAIGAGAGNPPAVVDETADIEKAARD
CCCCCEEEEECCCEEEEEECCCHHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHH
IIKGCSFDNNLPCVAEKEVIVVNQVADYLIHCMKKSGAYLLCDKKLSQQLQSLVLNEKGT
HHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCCCC
GPNTAFVGKDARYILQQLGIQVGDDIKVILIEAEKTHPFVVHELMMPVLPVVRVDNVDEA
CCCCEEECCHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHEEECCHHHE
IELAVKVEHGNRHTAVMHSTNVEKLTKMARLIQTTIFVKNGPSYAGLGVGGEGHATFTIA
EEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHEEEECCCCEECCCCCCCCCEEEEEE
GPTGEGLTSARSFARRRRCVMVEALNIR
CCCCCCHHHHHHHHHHHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]