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The map label for this gene is speC [H]

Identifier: 218691089

GI number: 218691089

Start: 3371460

End: 3373595

Strand: Reverse

Name: speC [H]

Synonym: ECED1_3428

Alternate gene names: 218691089

Gene position: 3373595-3371460 (Counterclockwise)

Preceding gene: 218691092

Following gene: 218691084

Centisome position: 64.76

GC content: 52.25

Gene sequence:

>2136_bases
ATGAAATCAATGAATATTGCCGCCAGTAGTGAACTGGTATCCCGACTTTCTACTCATCGCCGCGTGGTGGCGTTGGGAGA
TACTGATTTTACGGACGTCGCGGCAGTCGTCATTACCGCTGCGGATAGTCGCAGTGGCATTCTTGCGTTGCTTAAGCGCA
CCGGTTTTCATCTACCGGTGTTTTTGTATTCCGAACATGCTGTTGAATTACCTGCGGGCGTTACGGCGGTAATCAACGGC
AACGAGCAGCAGTGGCTGGAGCTGGAATCCGCAGCCTGTCAGTATGAAGAGAATTTGCTGCCACCGTTTTATGACACGCT
GACGCAGTACGTTGAGATGGGTAATAGCACCTTTGCTTGCCCTGGACATCAACATGGTGCGTTCTTTAAAAAGCATCCTG
CCGGACGCCATTTTTACGATTTCTTTGGCGAGAACATCTTTCGCGCCGATATGTGTAACGCTGACGTAAAATTGGGCGAT
CTGCTTATTCATGAAGGATCGGCGAAAGATGCGCAGAAATTTGCAGCCAAAGTCTTTCATGCCGATAAAACCTATTTTGT
GCTGAACGGCACATCGGCAGCGAATAAAGTGGTGACGAATGCGCTGTTAACGCGTGGCGATCTGGTGCTCTTCGACCGTA
ACAACCATAAGTCGAATCATCATGGCGCGTTGATTCAGGCGGGGGCGACGCCGGTCTATCTGGAAGCTTCACGTAACCCG
TTTGGTTTCATTGGCGGTATTGATGCGCACTGTTTTAATGAAGAGTATCTGCGCCAGCAAATTCGCGACGTTGCGCCAGA
AAAAGCCGACCTGCCGCGCCCGTTTCGCCTGGCGATTATTCAGCTGGGAACCTATGACGGCACTGTCTATAACGCCCGTC
AGGTGATCGATACCGTTGGGCATCTGTGTGATTACATTCTGTTTGATTCCGCGTGGGTCGGTTACGAACAGTTTATCCCG
ATGATGGCGGATAGCTCGCCGCTGCTGTTAGAACTTAACGAAAACGATCCGGGGATCTTTGTGACTCAGTCGGTGCACAA
ACAGCAGGCGGGATTCTCACAGACGTCGCAGATCCATAAAAAAGATAACCATATCCGTGGACAGGCGCGTTTTTGCCCGC
ATAAGCGGTTGAATAATGCCTTTATGCTCCATGCTTCTACCAGCCCGTTCTATCCGCTGTTCGCCGCCCTGGACGTTAAC
GCCAAAATTCATGAAGGGGAGAGTGGGCGTCGGCTGTGGGCTGAGTGCGTTGAGTTGGGTATTGAGTCGCGCAAGGCTAT
TCTTACGCGCTGTAAGCTGTTCCGCCCGTTTATCCCGCCCGTTGTTGATGGCAAATTGTGGCAGGATTATCCGACGTCAG
TGTTAGCCAGCGACCGCCGTTTTTTCAGTTTTGAGCCGGGGGCGAATTGGCACGGCTTTGAAGGATATGCCGCGGATCAG
TATTTTGTTGATCCGTGCAAGCTGTTACTCACTACGCCGGGTATCGATGCCGAAACCGGCGAATATAGCGACTTTGGCGT
TCCGGCGACGATTCTGGCGCACTACCTGCGTGAGAACGGCATTGTGCCGGAGAAGTGCGATCTCAACTCCATTCTGTTCT
TATTAACTCCGGCGGAAAGCCACGAGAAGCTGGCACAACTGGTGGCGATGCTGGCGCAGTTTGAACAGCATATTGAGGAT
GATTCGCCGCTGGCTGAGGTGTTGCCGAGCGTTTATAACAAATATCCGGTGCGCTATCGCGACTACACCCTGCGCCAGTT
GTGTCAGGAGATGCACGATTTGTATGTCAGTTTCGACGTCAAAGACCTACAAAAAGCGATGTTCCGCCAGCAGAGTTTCC
CGTCAGTGGTGATGAATCCCCAGGATGCGCATAGCGCTTATATTCGCGGTGAAGTGGAGTTGGTGCGGATTCGTGATGCC
GAAGGGCGAATTGCGGCAGAAGGGGCGTTGCCTTATCCACCTGGCGTGCTTTGCGTGGTACCCGGGGAAGTCTGGAGTGG
GGCGGTTCAACGTTATTTCCTTGCGCTGGAAGAAGGCGTGAATTTGTTGCCGGGATTTTCGCCGGAGTTGCAAGGTGTCT
ATAGCGAAACCGATGCGGATGGCATGAAACGGTTGTACGGTTATGTGTTGAAGTAA

Upstream 100 bases:

>100_bases
CTGGTGGTCGGAGCTGGTGACCAGTTTGACCCATATCTCATGGGGCAGGGTTTTCCACCTTGTCCGGTATTCTTACTTCC
CCTAAACGGGTTTTGCGCTT

Downstream 100 bases:

>100_bases
GAATAAAAAAACGGGTCACCTTCTGGCGACCCGTTTTTCTTTGCGTAATTAGTGGCTAACCGTCTGTGTACCTGTCGGGA
CACGAACGTGTTTATATTTG

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 711; Mature: 711

Protein sequence:

>711_residues
MKSMNIAASSELVSRLSTHRRVVALGDTDFTDVAAVVITAADSRSGILALLKRTGFHLPVFLYSEHAVELPAGVTAVING
NEQQWLELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENIFRADMCNADVKLGD
LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPVYLEASRNP
FGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIP
MMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVN
AKIHEGESGRRLWAECVELGIESRKAILTRCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGANWHGFEGYAADQ
YFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIED
DSPLAEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAHSAYIRGEVELVRIRDA
EGRIAAEGALPYPPGVLCVVPGEVWSGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGMKRLYGYVLK

Sequences:

>Translated_711_residues
MKSMNIAASSELVSRLSTHRRVVALGDTDFTDVAAVVITAADSRSGILALLKRTGFHLPVFLYSEHAVELPAGVTAVING
NEQQWLELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENIFRADMCNADVKLGD
LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPVYLEASRNP
FGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIP
MMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVN
AKIHEGESGRRLWAECVELGIESRKAILTRCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGANWHGFEGYAADQ
YFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIED
DSPLAEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAHSAYIRGEVELVRIRDA
EGRIAAEGALPYPPGVLCVVPGEVWSGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGMKRLYGYVLK
>Mature_711_residues
MKSMNIAASSELVSRLSTHRRVVALGDTDFTDVAAVVITAADSRSGILALLKRTGFHLPVFLYSEHAVELPAGVTAVING
NEQQWLELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENIFRADMCNADVKLGD
LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPVYLEASRNP
FGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIP
MMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVN
AKIHEGESGRRLWAECVELGIESRKAILTRCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGANWHGFEGYAADQ
YFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIED
DSPLAEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAHSAYIRGEVELVRIRDA
EGRIAAEGALPYPPGVLCVVPGEVWSGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGMKRLYGYVLK

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI87082193, Length=711, Percent_Identity=98.4528832630099, Blast_Score=1464, Evalue=0.0,
Organism=Escherichia coli, GI1786909, Length=719, Percent_Identity=67.1766342141864, Blast_Score=1015, Evalue=0.0,
Organism=Escherichia coli, GI221142684, Length=636, Percent_Identity=33.4905660377358, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1790573, Length=619, Percent_Identity=34.248788368336, Blast_Score=333, Evalue=3e-92,
Organism=Escherichia coli, GI1786384, Length=621, Percent_Identity=34.2995169082126, Blast_Score=330, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 79509; Mature: 79509

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSMNIAASSELVSRLSTHRRVVALGDTDFTDVAAVVITAADSRSGILALLKRTGFHLPV
CCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHEEEEEEECCCCCHHHHHHHHCCCCEEE
FLYSEHAVELPAGVTAVINGNEQQWLELESAACQYEENLLPPFYDTLTQYVEMGNSTFAC
EEECCCCEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEC
PGHQHGAFFKKHPAGRHFYDFFGENIFRADMCNADVKLGDLLIHEGSAKDAQKFAAKVFH
CCCCCCCCHHCCCCCCHHHHHHCCCEEEHHCCCCCCEECEEEEECCCCHHHHHHHHHHHC
ADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPVYLEASRNP
CCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCEEEEEECCCC
FGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFRLAIIQLGTYDGTVYNARQVIDTVG
CEEECCCCHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHH
HLCDYILFDSAWVGYEQFIPMMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHK
HHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHCCCHHHHHHHH
KDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGESGRRLWAECVELG
CCCCCCCCCCCCCHHHCCCEEEEEECCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHC
IESRKAILTRCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGANWHGFEGYAADQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCC
YFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAES
EECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHH
HEKLAQLVAMLAQFEQHIEDDSPLAEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDV
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHEEECCH
KDLQKAMFRQQSFPSVVMNPQDAHSAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLCVV
HHHHHHHHHHCCCCCEEECCCHHCCEEEECCEEEEEEECCCCCEEECCCCCCCCCEEEEE
PGEVWSGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGMKRLYGYVLK
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKSMNIAASSELVSRLSTHRRVVALGDTDFTDVAAVVITAADSRSGILALLKRTGFHLPV
CCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHEEEEEEECCCCCHHHHHHHHCCCCEEE
FLYSEHAVELPAGVTAVINGNEQQWLELESAACQYEENLLPPFYDTLTQYVEMGNSTFAC
EEECCCCEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEC
PGHQHGAFFKKHPAGRHFYDFFGENIFRADMCNADVKLGDLLIHEGSAKDAQKFAAKVFH
CCCCCCCCHHCCCCCCHHHHHHCCCEEEHHCCCCCCEECEEEEECCCCHHHHHHHHHHHC
ADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPVYLEASRNP
CCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCEEEEEECCCC
FGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFRLAIIQLGTYDGTVYNARQVIDTVG
CEEECCCCHHHCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHH
HLCDYILFDSAWVGYEQFIPMMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHK
HHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCCEEEEHHHHHHHCCCHHHHHHHH
KDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEGESGRRLWAECVELG
CCCCCCCCCCCCCHHHCCCEEEEEECCCCCCEEEEEEECCCEEECCCCCHHHHHHHHHHC
IESRKAILTRCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGANWHGFEGYAADQ
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCEEEEECCCCCCCCCCCCCCCC
YFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAES
EECCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHH
HEKLAQLVAMLAQFEQHIEDDSPLAEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDV
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHEEECCH
KDLQKAMFRQQSFPSVVMNPQDAHSAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLCVV
HHHHHHHHHHCCCCCEEECCCHHCCEEEECCEEEEEEECCCCCEEECCCCCCCCCEEEEE
PGEVWSGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGMKRLYGYVLK
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]