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The map label for this gene is ygcN [H]

Identifier: 218690886

GI number: 218690886

Start: 3148454

End: 3149725

Strand: Direct

Name: ygcN [H]

Synonym: ECED1_3215

Alternate gene names: 218690886

Gene position: 3148454-3149725 (Clockwise)

Preceding gene: 218690885

Following gene: 218690887

Centisome position: 60.44

GC content: 55.82

Gene sequence:

>1272_bases
ATGGAAGACGACTGCGACATTATTATTATCGGTGCCGGTATTGCTGGCACCGCTTGCGCGTTACGCTGCGCGCGAGCGGG
TTTATCCGTTTTGTTACTGGAACGAGCGGAGATTCCCGGCAGCAAAAATCTTTCCGGCGGGCGGCTATACACCCATGCGC
TCGCGGAACTCCTCCCGCAATTTCACCTGACCGCGCCTCTTGAACGACGCATCACTCACGAAAGTCTTTCTCTGTTAACG
CCAGATGGCGCAACGACGTTTTCCAGCTTACTGCCCGGCGGTGAATCCTGGAGTGTATTACGCGCACGATTCGATCCGTG
GCTGGTTGCCGAAGCCGAAAAAGAAGGTGTCGAATGCATCCCCGGTGCGACGGTAGATGCACTGTATGAAGAAAACGGCA
GGGTGTGTGGTGTCATTTGTGGTGACGATATTCTTCGCGCCCGTTATGTGGTGCTGGCAGAAGGTGCCAACAGCGTCCTG
GCGGAACGCCACGGGTTAGTGACTCGTCCTGCTGGCGAAGCGATGGCATTGGGGATCAAAGAAGTGCTGACGCTGGAACC
ATCCGCTATTGAAGAACGTTTTCATCTGGAGAATAACGAAGGCGCAGCGTTGTTGTTCAGCGGCGGGATCTGTGATGACT
TACCCGGCGGCGCATTTCTTTATACTAATCAACAAACGCTCTCGTTAGGGATTGTTTGCCCGCTCTCCTCCCTTACGCAA
AGTCGTGTTCCGGCAAGCGAGCTGCTGGCTCGCTTTAAAACGCATCCGGCAGTGCGCCCGCTTATCAAAAACACGGAATC
ACTGGAGTATGGTGCGCATCTGGTGCCAGAAGGTGGCCTGCGCAGTATGCCGGTGCAATACGCCGGTAACGGCTGGCTGC
TGGTGGGCGATGCGTTGCGCAGTTGCGTCAATACCGGAATTTCCGTGCGCGGTATGGATATGGCGCTAACTGGCGCGCAG
GCGGCGGCACAAACGCTGATAAGCGCCTGCCAGCACCGCGAGCCGCAAAATCTGTTTCCGCTTTATCATCACAACGTAGA
GCGCAGCCTGCTGTGGGATGTTCTACAGCGTTATCAGCATGTTCCGGCGCTTTTGCAACGCCCTGGCTGGTATCGGGTGT
GGTCTGGGTTAATGCAGGATATTTCCCGTGATTTATGGGATCAGGGGAATACACCTGTTCCACCGCTGCGCCAGTTGCTC
TGGCGTCATTTACGTCGTCACGGCTTGTGGCATCTGACGGGCGATGTTATCAGGAGTCTGCGATGTCTGTAG

Upstream 100 bases:

>100_bases
GTTGTATCTATCGCGGCGAATGATAAGAGTGTGTCGGCGGTCAATTTCCCTTAAGTAACGCTATGTTAGGGTGTTGTGTT
CTGGATATCTGGGGCATGAC

Downstream 100 bases:

>100_bases
CCCGTAATCTCTGGCGCGCTGCCGATGCGCCGCACATTGTTCCAGCTGACTCCGTTGAGCGCCAGACGGCACAACGGTTG
ATTAACGCCTGTCCAGCAGG

Product: putative oxidoreductase with FAD/NAD(P)-binding domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDGATTFSSLLPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLTLEPSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLRSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRVWSGLMQDISRDLWDQGNTPVPPLRQLL
WRHLRRHGLWHLTGDVIRSLRCL

Sequences:

>Translated_423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDGATTFSSLLPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLTLEPSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLRSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRVWSGLMQDISRDLWDQGNTPVPPLRQLL
WRHLRRHGLWHLTGDVIRSLRCL
>Mature_423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDGATTFSSLLPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLTLEPSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLRSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRVWSGLMQDISRDLWDQGNTPVPPLRQLL
WRHLRRHGLWHLTGDVIRSLRCL

Specific function: Probably accepts electrons from ygcQ/ygcR and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=403, Percent_Identity=24.8138957816377, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87082155, Length=423, Percent_Identity=96.2174940898345, Blast_Score=800, Evalue=0.0,
Organism=Escherichia coli, GI1787991, Length=428, Percent_Identity=41.588785046729, Blast_Score=338, Evalue=5e-94,
Organism=Escherichia coli, GI1786227, Length=428, Percent_Identity=40.6542056074766, Blast_Score=325, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI25144720, Length=424, Percent_Identity=25.9433962264151, Blast_Score=107, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324932, Length=367, Percent_Identity=26.9754768392371, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24652256, Length=408, Percent_Identity=26.4705882352941, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.5.5.-

Molecular weight: Translated: 46242; Mature: 46242

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
CCCCCCEEEEECCCHHHHHHHHHHHCCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHH
FHLTAPLERRITHESLSLLTPDGATTFSSLLPGGESWSVLRARFDPWLVAEAEKEGVECI
HCCCCCHHHHHHHHHHHEECCCCHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCEEC
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
CCCHHHHHHHCCCCEEEEEECCHHHHHEEEEEECCCHHHHHHHCCCEECCCCCHHHHHHH
EVLTLEPSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
HHHHCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCHHHHHH
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLRSMPVQYAGNGWLLVGDALR
HCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCEEEEHHHHH
SCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQH
HHHHCCCEEECCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
VPALLQRPGWYRVWSGLMQDISRDLWDQGNTPVPPLRQLLWRHLRRHGLWHLTGDVIRSL
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHH
RCL
CCC
>Mature Secondary Structure
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
CCCCCCEEEEECCCHHHHHHHHHHHCCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHH
FHLTAPLERRITHESLSLLTPDGATTFSSLLPGGESWSVLRARFDPWLVAEAEKEGVECI
HCCCCCHHHHHHHHHHHEECCCCHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCEEC
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
CCCHHHHHHHCCCCEEEEEECCHHHHHEEEEEECCCHHHHHHHCCCEECCCCCHHHHHHH
EVLTLEPSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
HHHHCCHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCHHHHHH
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLRSMPVQYAGNGWLLVGDALR
HCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCEEEEHHHHH
SCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQH
HHHHCCCEEECCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
VPALLQRPGWYRVWSGLMQDISRDLWDQGNTPVPPLRQLLWRHLRRHGLWHLTGDVIRSL
HHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECHHHHHHH
RCL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]