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The map label for this gene is yfaX [H]

Identifier: 218690411

GI number: 218690411

Start: 2651562

End: 2652344

Strand: Reverse

Name: yfaX [H]

Synonym: ECED1_2714

Alternate gene names: 218690411

Gene position: 2652344-2651562 (Counterclockwise)

Preceding gene: 218690412

Following gene: 218690410

Centisome position: 50.91

GC content: 50.7

Gene sequence:

>783_bases
ATGTTGGAATCAAGCAAAGTTCCCGCCCTGACACGGGCTATTGATATTCTCAATTTGATTGCCCGGATTGGCCCCTGTAG
TGCTGCGACGATCATTGACACATTGGGGATCCCTAAAAGCACAGCCTATTTGCTGCTTAATGAACTCAGGCGTCAGCGTT
TTCTTAGCCTTGATCATCAGGAAAATTTTTGTTTGTGGACCAGGCTGGTGGAGCTTTCCGGTCATGCGTTAAGCAAGATG
GATCTCCGGGAACTGGCTCGACCGCGTTTGACGCAACTGATGGATACCACCGGGCTGTTATGTCACCTGGGGATTATTGA
TAACGGCAGCGCTTATTACATTTTGAAAGTGGAGTCATCAGCCACTATCAGCGTGCGTTCCCATGAAGGAAAAAGCCTTT
CGCTTTATCGCTCCGGAATAGGTAAATGCCTGCTTGCCTGGCAACCTGCAGCTGTACAGCAAAGCATTATCGAAGGGCTG
GTCTGGGAACGGGCGACACCCACAACGATTACTCATCCACAGCAACTTCACGAAGAACTGGCGCGTATTCGCCGCCAGGG
CTGGAGCTATGACAACGGCGAAGATTACGCCGATGTCCGTTGTGTCGCTGCGCCGGTGTTTAACGCCAATAACGAGCTTA
CTGCTGCGATTTCGGTGGTCGGTACCCGCTTACAAATCAATGAAGAATACCGTGATTATCTGGCGGGCAAGGCCATTGCC
TGCGCCAGGGATATTTCACGTTTGTTGGGATGGAAAAGTCCCTTTGACTTACAGGCCTCATAA

Upstream 100 bases:

>100_bases
TCTCCAGTCCGCTGGACGAGAAACGGGATTTGATGCGCTTCACAATTTTACTCCCCCTGAGCAACGAGACTGATTCCAGT
ATCTAAGACTGGAGTCCAGT

Downstream 100 bases:

>100_bases
CAATGGAGAACATCATGACCCTACCAAAAATCAAACAGGTTCGCGCCTGGTTTACTGGCGGTGCGACAGCAGAAAAAGGC
GCTGGCGGCGGTGATTATCA

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYLLLNELRRQRFLSLDHQENFCLWTRLVELSGHALSKM
DLRELARPRLTQLMDTTGLLCHLGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGL
VWERATPTTITHPQQLHEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAISVVGTRLQINEEYRDYLAGKAIA
CARDISRLLGWKSPFDLQAS

Sequences:

>Translated_260_residues
MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYLLLNELRRQRFLSLDHQENFCLWTRLVELSGHALSKM
DLRELARPRLTQLMDTTGLLCHLGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGL
VWERATPTTITHPQQLHEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAISVVGTRLQINEEYRDYLAGKAIA
CARDISRLLGWKSPFDLQAS
>Mature_260_residues
MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYLLLNELRRQRFLSLDHQENFCLWTRLVELSGHALSKM
DLRELARPRLTQLMDTTGLLCHLGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGL
VWERATPTTITHPQQLHEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAISVVGTRLQINEEYRDYLAGKAIA
CARDISRLLGWKSPFDLQAS

Specific function: Unknown

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788581, Length=260, Percent_Identity=99.6153846153846, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1790752, Length=246, Percent_Identity=31.7073170731707, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788131, Length=222, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786468, Length=251, Percent_Identity=30.6772908366534, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI87082359, Length=251, Percent_Identity=24.7011952191235, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786715, Length=248, Percent_Identity=27.8225806451613, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789999, Length=238, Percent_Identity=26.890756302521, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28933; Mature: 28933

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYLLLNELRRQRFLSLDHQ
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
ENFCLWTRLVELSGHALSKMDLRELARPRLTQLMDTTGLLCHLGIIDNGSAYYILKVESS
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEECCC
ATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGLVWERATPTTITHPQQLHEEL
CEEEEECCCCCCHHHHHHCHHHEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAISVVGTRLQINEEYRDYLAGKAIA
HHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHEEECHHHHHHHHCCHHH
CARDISRLLGWKSPFDLQAS
HHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYLLLNELRRQRFLSLDHQ
CCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
ENFCLWTRLVELSGHALSKMDLRELARPRLTQLMDTTGLLCHLGIIDNGSAYYILKVESS
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEEEECCC
ATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGLVWERATPTTITHPQQLHEEL
CEEEEECCCCCCHHHHHHCHHHEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAISVVGTRLQINEEYRDYLAGKAIA
HHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHEEECHHHHHHHHCCHHH
CARDISRLLGWKSPFDLQAS
HHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]