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The map label for this gene is yfaV [H]

Identifier: 218690409

GI number: 218690409

Start: 2648996

End: 2650285

Strand: Reverse

Name: yfaV [H]

Synonym: ECED1_2712

Alternate gene names: 218690409

Gene position: 2650285-2648996 (Counterclockwise)

Preceding gene: 218690410

Following gene: 218690408

Centisome position: 50.87

GC content: 52.95

Gene sequence:

>1290_bases
ATGAGCACCGCTTTGCTTGACGCCGTGGTGAAGAAAAACCGCGCGCGTTTAATTCCGTTTATGTTGGCGCTGTATGTGCT
GGCGTTTCTCGACCGTTCGAATATTGGTTTTGCCAAACAGACCTACCAGATTGATACCGGGCTGAGTAATGAAGCTTATG
CGCTGGGAGCAGGCATTTTCTTTGTGGTATACGCGTTTCTGGGGGTTCCGGCGAATCTTTTGATGCGCAAACTGGGGGCA
AGAACCTGGATTGGTACGACAACACTGCTGTGGGGATTTCTTTCGGCTGCCATGGCATGGGCCGATACTGAAGCGAAATT
TCTGATTGTTCGCACTCTGCTTGGTGCTGCGGAGGCTGGGTTTTTCCCTGGTATGATTTATCTCACCTCGCAATGGTTTC
CGCAGCGTAATCGCGCCAGCATTATGGGGCTGTTCTATATGGGCGCACCGCTGGCGTTAACACTGGGATCACCGCTTTCT
GGCGCGCTGCTGGAGATGCATGGATTTATGGGGCATCCCGGCTGGTTCTGGATGTTTGTGATTGAAGGATTGTTGGCAGT
CGGCGCTGGGGTATTCACATTCTTTTGGCTTGATGACACACCGGAGCAGGCACGTTTTCTGAGTAAACAAGAAAAAACGT
TACTTATCAATCAACTGGCAAGTGAAGAACAACAGAAAGTGACTTCGCGACTGAGCGATGCGTTGCGTAATGGGCGAGTC
TGGCAACTGGCGATTATCTACCTGACCATTCAGGTGGCGGTTTACGGATTAATTTTCTTCCTGCCGACCCAGGTTGCTGC
ATTGCTGGGGACAAAAGTGGGCTTTACGGCGTCGGTGGTCACCGCCATTCCGTGGGTTGCGGCCTTGTTTGGGACCTGGC
TTATTCCGTGCTACTCCGATAAAACCGGCGAACGGCGTAATGTCGCAGCGCTGACATTACTGGCGGCGGGCATTGGTATT
GGTCTGTCCGGGCTGCTTTCTCCAGTACTGGCGATCGTAGCACTGTGTGTTGCAGCCATCGGGTTTATTGCCGTGCAACC
GGTGTTCTGGACGATGCCGACACAGCTTCTTTCCGGTACGGCGCTGGCTGCGGGGATTGGTTTTATAAACCTGTTTGGTG
CAGTGGGCGGGTTTATTGACCCGATCCTGCGCGTGAAAGCAGAAACGTTATTTTCCAGCGATGCGGCGGGATTACTGACG
CTGGCAGCGGTGGCGGTCATCGGTTCGCTGATTATTTTCACTCTGCGTGTAAATCGCACTGTTGCGCAGACCGACGTGGC
ACATCATTAA

Upstream 100 bases:

>100_bases
AACTCAATCGTGACTGCAATTTGAACCCCCCCTACAGCCACTAATCACTCCGGGCGTTGCTGTGACAACGGTAACGCCCA
CATATTCTAAGGAGCTTTTT

Downstream 100 bases:

>100_bases
ATAGTTTAAGGAACACGATGAACGCATTATTAACCAATCCCTTTAAAGAACGTTTACGCAAGGGCGAAGTGCAAATTGGT
CTGTGGTTAAGCTCAACGAC

Product: putative carboxylate transporter; phthalate permease family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MSTALLDAVVKKNRARLIPFMLALYVLAFLDRSNIGFAKQTYQIDTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKLGA
RTWIGTTTLLWGFLSAAMAWADTEAKFLIVRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
GALLEMHGFMGHPGWFWMFVIEGLLAVGAGVFTFFWLDDTPEQARFLSKQEKTLLINQLASEEQQKVTSRLSDALRNGRV
WQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAIPWVAALFGTWLIPCYSDKTGERRNVAALTLLAAGIGI
GLSGLLSPVLAIVALCVAAIGFIAVQPVFWTMPTQLLSGTALAAGIGFINLFGAVGGFIDPILRVKAETLFSSDAAGLLT
LAAVAVIGSLIIFTLRVNRTVAQTDVAHH

Sequences:

>Translated_429_residues
MSTALLDAVVKKNRARLIPFMLALYVLAFLDRSNIGFAKQTYQIDTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKLGA
RTWIGTTTLLWGFLSAAMAWADTEAKFLIVRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
GALLEMHGFMGHPGWFWMFVIEGLLAVGAGVFTFFWLDDTPEQARFLSKQEKTLLINQLASEEQQKVTSRLSDALRNGRV
WQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAIPWVAALFGTWLIPCYSDKTGERRNVAALTLLAAGIGI
GLSGLLSPVLAIVALCVAAIGFIAVQPVFWTMPTQLLSGTALAAGIGFINLFGAVGGFIDPILRVKAETLFSSDAAGLLT
LAAVAVIGSLIIFTLRVNRTVAQTDVAHH
>Mature_428_residues
STALLDAVVKKNRARLIPFMLALYVLAFLDRSNIGFAKQTYQIDTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKLGAR
TWIGTTTLLWGFLSAAMAWADTEAKFLIVRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLSG
ALLEMHGFMGHPGWFWMFVIEGLLAVGAGVFTFFWLDDTPEQARFLSKQEKTLLINQLASEEQQKVTSRLSDALRNGRVW
QLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAIPWVAALFGTWLIPCYSDKTGERRNVAALTLLAAGIGIG
LSGLLSPVLAIVALCVAAIGFIAVQPVFWTMPTQLLSGTALAAGIGFINLFGAVGGFIDPILRVKAETLFSSDAAGLLTL
AAVAVIGSLIIFTLRVNRTVAQTDVAHH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=423, Percent_Identity=25.0591016548463, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082071, Length=429, Percent_Identity=98.3682983682984, Blast_Score=835, Evalue=0.0,
Organism=Escherichia coli, GI2367193, Length=441, Percent_Identity=23.3560090702948, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI87082320, Length=420, Percent_Identity=21.6666666666667, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789152, Length=417, Percent_Identity=23.7410071942446, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI2367379, Length=268, Percent_Identity=22.0149253731343, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71991453, Length=335, Percent_Identity=25.6716417910448, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=335, Percent_Identity=25.6716417910448, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=219, Percent_Identity=26.4840182648402, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323032, Length=222, Percent_Identity=29.2792792792793, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321698, Length=281, Percent_Identity=24.5551601423488, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322612, Length=271, Percent_Identity=22.5092250922509, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI20130167, Length=255, Percent_Identity=27.4509803921569, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46170; Mature: 46039

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTALLDAVVKKNRARLIPFMLALYVLAFLDRSNIGFAKQTYQIDTGLSNEAYALGAGIF
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEEECCCCCCCHHHHHHHHH
FVVYAFLGVPANLLMRKLGARTWIGTTTLLWGFLSAAMAWADTEAKFLIVRTLLGAAEAG
HHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
FFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLSGALLEMHGFMGHPGWFWMFV
CCCCHHEEECCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHH
IEGLLAVGAGVFTFFWLDDTPEQARFLSKQEKTLLINQLASEEQQKVTSRLSDALRNGRV
HHHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAIPWVAALFGTWLIPCYSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCC
KTGERRNVAALTLLAAGIGIGLSGLLSPVLAIVALCVAAIGFIAVQPVFWTMPTQLLSGT
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALAAGIGFINLFGAVGGFIDPILRVKAETLFSSDAAGLLTLAAVAVIGSLIIFTLRVNRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
VAQTDVAHH
HHHHHCCCC
>Mature Secondary Structure 
STALLDAVVKKNRARLIPFMLALYVLAFLDRSNIGFAKQTYQIDTGLSNEAYALGAGIF
CHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHEEEECCCCCCCHHHHHHHHH
FVVYAFLGVPANLLMRKLGARTWIGTTTLLWGFLSAAMAWADTEAKFLIVRTLLGAAEAG
HHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCC
FFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLSGALLEMHGFMGHPGWFWMFV
CCCCHHEEECCCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCCCCHHHHHHH
IEGLLAVGAGVFTFFWLDDTPEQARFLSKQEKTLLINQLASEEQQKVTSRLSDALRNGRV
HHHHHHHCCHHHEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFTASVVTAIPWVAALFGTWLIPCYSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHEEECCCC
KTGERRNVAALTLLAAGIGIGLSGLLSPVLAIVALCVAAIGFIAVQPVFWTMPTQLLSGT
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ALAAGIGFINLFGAVGGFIDPILRVKAETLFSSDAAGLLTLAAVAVIGSLIIFTLRVNRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCH
VAQTDVAHH
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]