Click here to switch to the map view.

The map label for this gene is yeiC [H]

Identifier: 218690316

GI number: 218690316

Start: 2540892

End: 2541947

Strand: Reverse

Name: yeiC [H]

Synonym: ECED1_2614

Alternate gene names: 218690316

Gene position: 2541947-2540892 (Counterclockwise)

Preceding gene: 218690317

Following gene: 218690315

Centisome position: 48.79

GC content: 44.89

Gene sequence:

>1056_bases
ATGCTTATTATGAACATGTGTTTAAATCTGAACACGTGTTCTAATAGTCTTATTGACTGTAATGACTATTTTACCCAATT
TCTTCGTTGGCAATTTATTGCCAGGGGGCGTGCTATGCGCGAAAAGGACTACATAGTAATTATTGGCTCGGCGAATATTG
ATGTGGCTGGGTATTCACATCATCCATTGAATTATGCGGATTCGAATCCCGGAAAAATTAAATTTACCCCAGGTGGCGTG
GGAAGGAATATCGCTCATAATCTGGCGTTACTGGGGAAAAATGCCTGGCTTTTAAGTGCAGTAGGTGGTGATTTTTATGG
GCAATCATTACTGGCGCAAACTAATCAATCCGGTGTTTATGTCGATAAATGCTTAATTGTTCCGGGTGAGAATACATCCA
GCTATTTATCACTGCTCGATAATACAGGAGAAATGCTTGTCGCGATAAATGATATGAGTATTAGTGACTGTATTTCTGCA
GAATTTCTTGCCCAGCATCAGGAGTTTATTCGCGGTGCAAAGGTTATTGTCGCGGATTGCAACCTTAGTGAAGAGGCGCT
GGTCTGGGTTCTGGAAAATAGCGGGGAAACGCCTGTATTTATTGATCCGGTATCGGCATGGAAATGCGTCAAAATCCGCG
ATCATCTGAGCAAAATCCATACGTTAAAACCTAACCGTCTTGAAGCCGAAACGTTGAGCGGAATTGCACTTTCCGGACGT
GAAGATGTCGCAAAGGTCGCCGCCTGGTTTCATCAACACGGCCTGAACCGCCTGGTGCTGAGCATGGGAGGGGATGGCGT
TTACTACAGTGATATCAACGGTGAAAGTGGGTGGTCGGCCCCTATTAAAACTAATGTCATCAATGTTACTGGGGCAGGCG
ACGCCATGATGGCGGGGCTGGCCTCCTGTTGGGTAGACGGTATGCCGTTTATCGATTCTGTTCGATTTGCGCAGGGATGT
TCGTCAATGGCACTTGCCTGTGAATATACCAACAACCCTGAATTATCAATTGCCAATGTTACATCGTTAGTGGAGAACAC
AGAATGTCTGAATTAA

Upstream 100 bases:

>100_bases
ACAACTTTCTCTTTTGTTGCTGCATAAATAGACAAATTTTGTGACCGCCTTCATATCTGGCCGATTTCGTTTTTTCTGAT
CGATTTACATTGCGTTAAAC

Downstream 100 bases:

>100_bases
CTCTGTCCCCTGAATTATTACAAATATCCGCTGAAGTACAGGATGCTTTAAAAAATAAAAAACCGGTTGTTGCGCTGGAA
TCGACCATAATTTCTCACGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MLIMNMCLNLNTCSNSLIDCNDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSHHPLNYADSNPGKIKFTPGGV
GRNIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDKCLIVPGENTSSYLSLLDNTGEMLVAINDMSISDCISA
EFLAQHQEFIRGAKVIVADCNLSEEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGR
EDVAKVAAWFHQHGLNRLVLSMGGDGVYYSDINGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFIDSVRFAQGC
SSMALACEYTNNPELSIANVTSLVENTECLN

Sequences:

>Translated_351_residues
MLIMNMCLNLNTCSNSLIDCNDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSHHPLNYADSNPGKIKFTPGGV
GRNIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDKCLIVPGENTSSYLSLLDNTGEMLVAINDMSISDCISA
EFLAQHQEFIRGAKVIVADCNLSEEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGR
EDVAKVAAWFHQHGLNRLVLSMGGDGVYYSDINGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFIDSVRFAQGC
SSMALACEYTNNPELSIANVTSLVENTECLN
>Mature_351_residues
MLIMNMCLNLNTCSNSLIDCNDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSHHPLNYADSNPGKIKFTPGGV
GRNIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDKCLIVPGENTSSYLSLLDNTGEMLVAINDMSISDCISA
EFLAQHQEFIRGAKVIVADCNLSEEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGR
EDVAKVAAWFHQHGLNRLVLSMGGDGVYYSDINGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFIDSVRFAQGC
SSMALACEYTNNPELSIANVTSLVENTECLN

Specific function: Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788491, Length=313, Percent_Identity=88.4984025559105, Blast_Score=580, Evalue=1e-167,
Organism=Escherichia coli, GI1788484, Length=311, Percent_Identity=40.5144694533762, Blast_Score=234, Evalue=6e-63,
Organism=Escherichia coli, GI1790193, Length=281, Percent_Identity=23.8434163701068, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17532905, Length=296, Percent_Identity=24.3243243243243, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24580669, Length=278, Percent_Identity=29.4964028776978, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.83 [H]

Molecular weight: Translated: 38131; Mature: 38131

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIMNMCLNLNTCSNSLIDCNDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSH
CEEEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCC
HPLNYADSNPGKIKFTPGGVGRNIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVY
CCCCCCCCCCCEEEECCCCCCCHHHHHHHEECCCCEEEEECCCCHHCCHHHHHCCCCCEE
VDKCLIVPGENTSSYLSLLDNTGEMLVAINDMSISDCISAEFLAQHQEFIRGAKVIVADC
EEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
NLSEEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGR
CCCCCEEEEEEECCCCCCEEECCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHCCEEECCH
EDVAKVAAWFHQHGLNRLVLSMGGDGVYYSDINGESGWSAPIKTNVINVTGAGDAMMAGL
HHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHH
ASCWVDGMPFIDSVRFAQGCSSMALACEYTNNPELSIANVTSLVENTECLN
HHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLIMNMCLNLNTCSNSLIDCNDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSH
CEEEEEEECCCCCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCC
HPLNYADSNPGKIKFTPGGVGRNIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVY
CCCCCCCCCCCEEEECCCCCCCHHHHHHHEECCCCEEEEECCCCHHCCHHHHHCCCCCEE
VDKCLIVPGENTSSYLSLLDNTGEMLVAINDMSISDCISAEFLAQHQEFIRGAKVIVADC
EEEEEEEECCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEEC
NLSEEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGR
CCCCCEEEEEEECCCCCCEEECCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHCCEEECCH
EDVAKVAAWFHQHGLNRLVLSMGGDGVYYSDINGESGWSAPIKTNVINVTGAGDAMMAGL
HHHHHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHH
ASCWVDGMPFIDSVRFAQGCSSMALACEYTNNPELSIANVTSLVENTECLN
HHHHCCCCCHHHHHHHHHCCCCEEEEEEECCCCCEEHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 3076173 [H]