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The map label for this gene is gapC [H]

Identifier: 218689350

GI number: 218689350

Start: 1557794

End: 1558795

Strand: Reverse

Name: gapC [H]

Synonym: ECED1_1574

Alternate gene names: 218689350

Gene position: 1558795-1557794 (Counterclockwise)

Preceding gene: 218689353

Following gene: 218689346

Centisome position: 29.92

GC content: 48.4

Gene sequence:

>1002_bases
ATGAGTAAAGTTGGTATTAATGGTTTTGGTCGTATCGGTCGACTGGTGTTGCGTCGATTACTTGAAGTCAAAAGCAACAT
AGACGTTGTCGCTATTAATGATCTCACTTCCCCAAAAATTCTCGCCTACCTGCTGAAACATGATTCAAACTACGGACCGT
TCCCCTGGAGCGTTGATTATACGGAAGATTCACTTATCGTTGATGGGAAAAGTATCGCGGTTTACGCCGAAAAAGAGGCT
AAAAATATTCTGTGGAAAGCGAAAGGCGCAGAAATCATTGTCGAATGTACTGGCTTTTATACCTCCGCCGAGAAATCGCA
GGCGCATCTTGATGCTGGCGCGAAGAAGGTGTTGATTTCCGCCCCTGCCGGTGAAATGAAAACCATCGTTTATAACGTCA
ATGACGACACTCTGGATGGCAACGACACCATTGTTTCCGTGGCGTCATGCACCACTAACTGCCTTGCGCCGATGACCAAA
GCCTTGCATGACAGTTTCGGGATAGAAGTCGGCACGATGACGACCATTCATGCCTATACCGGCACCCAGTCACTGGTGGA
TGGCCCACGTGGTAAAGATTTACGTGCTTCACGCGCAGCGGCAGAAAATATCATTCCCCACACTACGGGGGCGGCAAAAG
CCATTGGTCTGGTGATCCCGGAATTGAGCGGCAAACTGAAAGGTCATGCGCAACGCGTGCCGGTGAAAACAGGTTCGGTC
ACTGAACTGGTGTCGATTCTCGGAAAAAAAGTGACTGCCGAAGAGGTGAACAACGCGCTTAAAAAGGCGACAAACAATAA
CGAGTCATTTGGTTATACCGATGAAGAAATAGTCTCTTCCGATATCATTGGCAGCCATTTCGGTTCGGTGTTTGATGCCA
CGCAAACGGAAATTACCGCCGTGGGCGATTTACAACTGGTGAAAACGGTCGCCTGGTACGATAACGAATATGGCTTCGTC
ACGCAGCTTATTCGCACCCTCGAAAAATTCGCTAAACTCTGA

Upstream 100 bases:

>100_bases
TTACGTTTCACTGCAAGAATGTAGATTGCCCATCCCGCCATCCTGGTCTAAGCCTGGAAAGGATCAATTTTCATCCGAAC
GTTCCTGACAGGAGAAGACC

Downstream 100 bases:

>100_bases
CGCGCACAGGCGGAGGAAAAAACCTCCGCCTCTTTCACTCATTACGACTGTAAATAAACCACCTGGGTCTGCAGATATTC
ATGCAAGCCATGTTTACCAT

Product: glyceraldehyde-3-phosphate dehydrogenase C

Products: NA

Alternate protein names: GAPDH-C [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDYTEDSLIVDGKSIAVYAEKEA
KNILWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMTK
ALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSV
TELVSILGKKVTAEEVNNALKKATNNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFV
TQLIRTLEKFAKL

Sequences:

>Translated_333_residues
MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDYTEDSLIVDGKSIAVYAEKEA
KNILWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMTK
ALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSV
TELVSILGKKVTAEEVNNALKKATNNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFV
TQLIRTLEKFAKL
>Mature_332_residues
SKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDYTEDSLIVDGKSIAVYAEKEAK
NILWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMTKA
LHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSVT
ELVSILGKKVTAEEVNNALKKATNNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFVT
QLIRTLEKFAKL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=331, Percent_Identity=45.619335347432, Blast_Score=278, Evalue=4e-75,
Organism=Homo sapiens, GI7669492, Length=332, Percent_Identity=43.9759036144578, Blast_Score=274, Evalue=7e-74,
Organism=Escherichia coli, GI1788079, Length=333, Percent_Identity=45.945945945946, Blast_Score=277, Evalue=7e-76,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=40.3030303030303, Blast_Score=235, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=45.9940652818991, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=45.9940652818991, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=47.4626865671642, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=46.865671641791, Blast_Score=274, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=44.9404761904762, Blast_Score=289, Evalue=5e-79,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=45.7227138643068, Blast_Score=285, Evalue=6e-78,
Organism=Saccharomyces cerevisiae, GI6322409, Length=336, Percent_Identity=44.3452380952381, Blast_Score=281, Evalue=8e-77,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=45.8715596330275, Blast_Score=286, Evalue=1e-77,
Organism=Drosophila melanogaster, GI17933600, Length=331, Percent_Identity=47.1299093655589, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI18110149, Length=331, Percent_Identity=47.1299093655589, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI85725000, Length=331, Percent_Identity=46.5256797583082, Blast_Score=280, Evalue=8e-76,
Organism=Drosophila melanogaster, GI22023983, Length=331, Percent_Identity=46.5256797583082, Blast_Score=280, Evalue=8e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35824; Mature: 35693

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00071 GAPDH ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDY
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEECC
TEDSLIVDGKSIAVYAEKEAKNILWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLIS
CCCCEEECCCEEEEEECCCCCCEEEEECCCEEEEEECCCCCCCCHHHHHHCCCCCEEEEE
APAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMTKALHDSFGIEVGTMTTIHAYT
CCCCCEEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCEEECCEEEEEEEC
GTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSV
CCHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEECCCCCCCCCCCEECCCCCCCH
TELVSILGKKVTAEEVNNALKKATNNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITA
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
VGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDY
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCCEECC
TEDSLIVDGKSIAVYAEKEAKNILWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLIS
CCCCEEECCCEEEEEECCCCCCEEEEECCCEEEEEECCCCCCCCHHHHHHCCCCCEEEEE
APAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMTKALHDSFGIEVGTMTTIHAYT
CCCCCEEEEEEECCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCEEECCEEEEEEEC
GTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSV
CCHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHEEECCCCCCCCCCCEECCCCCCCH
TELVSILGKKVTAEEVNNALKKATNNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITA
HHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
VGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL
ECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]