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The map label for this gene is iolC [H]

Identifier: 218688159

GI number: 218688159

Start: 328589

End: 330526

Strand: Reverse

Name: iolC [H]

Synonym: ECED1_0311

Alternate gene names: 218688159

Gene position: 330526-328589 (Counterclockwise)

Preceding gene: 218688163

Following gene: 218688158

Centisome position: 6.34

GC content: 56.09

Gene sequence:

>1938_bases
ATGTCAATGAATAAAGCAGTCAGTAGTGAGCAAAAGCCGCTGGACGTTATCTGTCTGGGACGAGTCGCTGTTGATTTGTA
TGGTCAACAAATCGGGTCGCGGCTGGAGGATATGACGACTTTCGCTAAATATTTAGGGGGATCGTCAGGCAATGTTGCCT
ACGGCACGGCCATTCAGGGATTACGTTCCGCTATGCTGGCCCGCGTCGGCGATGAGCATATGGGACGTTTCGTTCGTGAA
GAATTAAACCGCGTTGGTGTGGATACGCAGTGCCTGCTGTCGGATCGCGATCGTCTGACCGCGCTGGTGATCCTCGGCAT
TAAAGATCAGGACACCTTTCCTCTGATCTTCTACCGCGATAACTGCGCGGACATGGCGCTAACACCCGAGGATATCCGCG
AAGATTACATCGCTTCTTCACGCGCATTAGCCGTCACTGGTACCCATCTTTCTCACCCCAATACGCGCGCCGCCGTTCTT
AAAGCACTGGAGTATGCGCAAAAACACGGGCTGCGGCGGGTGCTGGATATCGACTACCGCCCCGTACTGTGGGGCCTGAC
GTCGCTAGGAGACGGTGAAACGCGTTTCATCGCCTCATCACAGGTTACCGAACAGCTCCAGCAGGTATTGCGCCATTTCG
ATCTGATCGTTGGGACCGAAGAAGAATTCCATATCGCCGGCGGCAGTACCGACACGCTGACCGCCCTGCGGCGCGTCCGT
CAGTTGACCCAAGCCGTACTGGTGTGCAAACGCGGCGCGCTGGGCTGCTCAGTCTTTGAAGGCAACATTGCCGATGACTG
GTCGCAGGTGAAGATACATAGCGGCGTTCGCGTAGACGTTCTGAACGTTCTGGGCGCGGGCGATGCCTTTATGTCAGGAC
TGCTGCGGGGATACCTGAACGATGAAAGCTGGGAGCAAGCCTGCCGTTATGCAAACGCCTGCGGCGCGTTAGTGGTATCG
CGCCACGGTTGTGCCCCCGCCATGCCAACCAAAAAAGAGCTGGACGACTACCTCGCGCGTGAACAATCCATCACCCGGCC
AGACAAAGACCCGCGGCTGAATCACCTTCATCGGGTCACAACCCGTAAACAGCACTGGCCGGAGCTGTGCGTATTCGCCT
TCGACCATCGCAAGCAACTGGTGGATATCGCAAATGAAGTCGGCGCCAGTGAATCCGCGATCCCCCCTCTGAAGATGCTA
CTGCTGGAAGGGGCGCGTCAGGCGGCGCTTGAGGCCGGTTTACAGAATAATAGCGGCATCCTTGCCGATACCACCTTTGG
TCAGCAGGCGCTTAACGACGTGACCGGCCAGGGATGGTGGATTGGCCGACCGGTTGAGATGCCCGGTTCGTATCCGCTGA
AGCTGGAACATGGCGATATTGGCTCTCAGCTTGTCAGCTGGCCGCAAGAGCACGTCGTGAAATGTCTGGTCTTCTATCAT
CCACTCGATGCAGAGTCGGTACGTCTTGAACAAGAGGCGCTCATTGACGAGGTTTACCGCGCCTGCTGCCAGTCTGGTCA
CGATCTGCTGCTGGAAGTCATCTTGCCGCGCGATACGGCAGACCAAAATGAGCAATACTATCCTCAGATTGTGGAACGTT
TTTATCAACTGGGGATCCTGCCGGACTGGTGGAAACTGCCACCGTTAAGCCCAGATCGTTGGCGAGAAATCAGCCAGCAT
ATTGAGCATTATGACCCTGAATGTCGCGGTATATTGATACTTGGCCTGGACGCACCGGAAAGCGAGTTGAAGTCAGGATT
CGCCGCAGCAGCGGATATGCCCTGGGTGAAAGGTTTCGCCGTCGGCCGGACCATCTTTGGCGAACCGTCACGCCAGTGGT
TAGGCGGCCAGCTTAACGATGAACAGCTCATCGCAACGGTGAAACAAAAATACCGCATGCTTATTGACTACTGGCGCGAA
TACCGCCCGGCACGTTAA

Upstream 100 bases:

>100_bases
TTATTCAAACAATAAATGAAAACGTCATTCCATTTTTATTGAAAATGAAATCACCAAACCTTAGTATAAGCAAAAATAAC
ACCGTCTTCTGTTAGGGGAT

Downstream 100 bases:

>100_bases
TGCCTGCCTCATCACGCCCCGTGTCTGCATCGGACAAGGGGCGTGTTCGAGTAGGCAGCCTGGCGGCTGCGGCTTGTCAT
GACCTGATATTACCGTTATA

Product: putative carbohydrate kinase

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MSMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQGLRSAMLARVGDEHMGRFVRE
ELNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRDNCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVL
KALEYAQKHGLRRVLDIDYRPVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVR
QLTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLNDESWEQACRYANACGALVVS
RHGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVTTRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKML
LLEGARQAALEAGLQNNSGILADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYH
PLDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGILPDWWKLPPLSPDRWREISQH
IEHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFAVGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWRE
YRPAR

Sequences:

>Translated_645_residues
MSMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQGLRSAMLARVGDEHMGRFVRE
ELNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRDNCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVL
KALEYAQKHGLRRVLDIDYRPVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVR
QLTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLNDESWEQACRYANACGALVVS
RHGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVTTRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKML
LLEGARQAALEAGLQNNSGILADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYH
PLDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGILPDWWKLPPLSPDRWREISQH
IEHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFAVGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWRE
YRPAR
>Mature_644_residues
SMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQGLRSAMLARVGDEHMGRFVREE
LNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRDNCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVLK
ALEYAQKHGLRRVLDIDYRPVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVRQ
LTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLNDESWEQACRYANACGALVVSR
HGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVTTRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKMLL
LEGARQAALEAGLQNNSGILADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYHP
LDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGILPDWWKLPPLSPDRWREISQHI
EHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFAVGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWREY
RPAR

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 72219; Mature: 72088

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQG
CCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHH
LRSAMLARVGDEHMGRFVREELNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRD
HHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEC
NCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVLKALEYAQKHGLRRVLDIDYR
CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCC
PVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVR
HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHH
QLTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLN
HHHHHHHHHHCCCCEEEEEECCCCCCCHHEEECCCCEEEHHHHHCCCHHHHHHHHHHHCC
DESWEQACRYANACGALVVSRHGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKMLLLEGARQAALEAGLQNNSGI
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
LADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYH
EEECCHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHC
PLDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGIL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEECCCCCCCCCCHHHHHHHHHHHCCCC
PDWWKLPPLSPDRWREISQHIEHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCHHHHCCCCHHHHHH
VGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWREYRPAR
HCCHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SMNKAVSSEQKPLDVICLGRVAVDLYGQQIGSRLEDMTTFAKYLGGSSGNVAYGTAIQG
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHH
LRSAMLARVGDEHMGRFVREELNRVGVDTQCLLSDRDRLTALVILGIKDQDTFPLIFYRD
HHHHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEEEEECCCCCCEEEEEEC
NCADMALTPEDIREDYIASSRALAVTGTHLSHPNTRAAVLKALEYAQKHGLRRVLDIDYR
CCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHCCCCC
PVLWGLTSLGDGETRFIASSQVTEQLQQVLRHFDLIVGTEEEFHIAGGSTDTLTALRRVR
HHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHH
QLTQAVLVCKRGALGCSVFEGNIADDWSQVKIHSGVRVDVLNVLGAGDAFMSGLLRGYLN
HHHHHHHHHHCCCCEEEEEECCCCCCCHHEEECCCCEEEHHHHHCCCHHHHHHHHHHHCC
DESWEQACRYANACGALVVSRHGCAPAMPTKKELDDYLAREQSITRPDKDPRLNHLHRVT
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TRKQHWPELCVFAFDHRKQLVDIANEVGASESAIPPLKMLLLEGARQAALEAGLQNNSGI
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
LADTTFGQQALNDVTGQGWWIGRPVEMPGSYPLKLEHGDIGSQLVSWPQEHVVKCLVFYH
EEECCHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHHHC
PLDAESVRLEQEALIDEVYRACCQSGHDLLLEVILPRDTADQNEQYYPQIVERFYQLGIL
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEHEEECCCCCCCCCCHHHHHHHHHHHCCCC
PDWWKLPPLSPDRWREISQHIEHYDPECRGILILGLDAPESELKSGFAAAADMPWVKGFA
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHCCHHHHCCCCHHHHHH
VGRTIFGEPSRQWLGGQLNDEQLIATVKQKYRMLIDYWREYRPAR
HCCHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA