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The map label for this gene is alsK [H]

Identifier: 218551503

GI number: 218551503

Start: 4388888

End: 4389826

Strand: Direct

Name: alsK [H]

Synonym: EFER_4286

Alternate gene names: 218551503

Gene position: 4388888-4389826 (Clockwise)

Preceding gene: 218551502

Following gene: 218551504

Centisome position: 95.65

GC content: 52.61

Gene sequence:

>939_bases
ATGCCCGTAAAGGAGTGCAGAGTTATGGCTAAACAGCGTAGCGTGGTGGCGGGCGTGGATATGGGGGCGACTCATATCCG
CTTTTGCCTGCAAACGGCTGCGGGGGAGATTGTGCATTGCGAAAAGCGCCGTACCGCAGATGTATTGGTCCCCGATGTCG
CCAGCGGAATCGCTGCTATGCTGCATCAACAGTTCGTGCATTACGATGTGACCTGTTGTGGGCTAATCATGGGTTTACCG
GCACTGGTTGGCAAAGATCAACGCAGCATTATTTCGACTCCCAACTTGCCATTGTCGGCCGGGGAGCTACATGGCCTGGC
TGATAACCTGCAAGCTTCACTGAAATGCCCGTTAGCATTTTCCCGTGATGTAAACCTGCAACTCTCCTGGGATGTGCAGG
AAAATCATCTGGTCGATCAACTGGTCCTGGGAGCCTATCTGGGAACCGGAATGGGATTTGCCATCTGGATGAATGGTGCG
CCATGGACCGGGGCGCATGGTGTTGCAGGAGAATTAGGGCACATACCGCAAGGTGATATGACTCAACACTGTGGCTGTGG
CAACTCTGGCTGCCTTGAGACAGTCTGTTCGGGGCTGGCATTAAAACGGTGGTATGAACAACAACCTCGTAACTACACCT
TGAGCGAGTTGTTTGTCCATGCCAGTGATGAGTTGTTTGTGCAGTCGCTGCTCGATCACGCCGCTCGCGCAATTGCTTCC
AGCGTAAATTTGTTTGATCCCGATGTGGTGATTCTCGGTGGCGGTGTAATGGATATGGTAGCGTTTCCGCGAGAAGCATT
GATTGACAAAATTAAGTGTTATTTGCGCCGCCCGTTACCGTATCAGGAAGTCTGTTTTATTCCGGCATCGTCTTCGGCAT
TTAATGGTGCGCAAGGGGCCGCGACACTGGCAAGCGGACGTTTCTTTGCGAAGCAATGA

Upstream 100 bases:

>100_bases
GCGGCAGGTGCGGACGTGTTTATCGTTGGCACATCCGGGCTGTTTAATCATGCAGATAATATTACTGATGCCTGGCAGGT
AATGACCACGCAGATCCTCA

Downstream 100 bases:

>100_bases
TATTTACAGGACTCAGTGGTGCTGAATATATAATTTTCATATGAATTACATATATACATTATCCACGCAAATCTATTTGC
TATTGCGGGAAAAGTTCGCA

Product: D-allose kinase

Products: NA

Alternate protein names: Allokinase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MPVKECRVMAKQRSVVAGVDMGATHIRFCLQTAAGEIVHCEKRRTADVLVPDVASGIAAMLHQQFVHYDVTCCGLIMGLP
ALVGKDQRSIISTPNLPLSAGELHGLADNLQASLKCPLAFSRDVNLQLSWDVQENHLVDQLVLGAYLGTGMGFAIWMNGA
PWTGAHGVAGELGHIPQGDMTQHCGCGNSGCLETVCSGLALKRWYEQQPRNYTLSELFVHASDELFVQSLLDHAARAIAS
SVNLFDPDVVILGGGVMDMVAFPREALIDKIKCYLRRPLPYQEVCFIPASSSAFNGAQGAATLASGRFFAKQ

Sequences:

>Translated_312_residues
MPVKECRVMAKQRSVVAGVDMGATHIRFCLQTAAGEIVHCEKRRTADVLVPDVASGIAAMLHQQFVHYDVTCCGLIMGLP
ALVGKDQRSIISTPNLPLSAGELHGLADNLQASLKCPLAFSRDVNLQLSWDVQENHLVDQLVLGAYLGTGMGFAIWMNGA
PWTGAHGVAGELGHIPQGDMTQHCGCGNSGCLETVCSGLALKRWYEQQPRNYTLSELFVHASDELFVQSLLDHAARAIAS
SVNLFDPDVVILGGGVMDMVAFPREALIDKIKCYLRRPLPYQEVCFIPASSSAFNGAQGAATLASGRFFAKQ
>Mature_311_residues
PVKECRVMAKQRSVVAGVDMGATHIRFCLQTAAGEIVHCEKRRTADVLVPDVASGIAAMLHQQFVHYDVTCCGLIMGLPA
LVGKDQRSIISTPNLPLSAGELHGLADNLQASLKCPLAFSRDVNLQLSWDVQENHLVDQLVLGAYLGTGMGFAIWMNGAP
WTGAHGVAGELGHIPQGDMTQHCGCGNSGCLETVCSGLALKRWYEQQPRNYTLSELFVHASDELFVQSLLDHAARAIASS
VNLFDPDVVILGGGVMDMVAFPREALIDKIKCYLRRPLPYQEVCFIPASSSAFNGAQGAATLASGRFFAKQ

Specific function: Catalyzes the phosphorylation of D-allose to D-allose 6- P. Has also low level glucokinase activity in vitro [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1790522, Length=303, Percent_Identity=71.2871287128713, Blast_Score=459, Evalue=1e-131,
Organism=Escherichia coli, GI1787363, Length=311, Percent_Identity=27.6527331189711, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081733, Length=167, Percent_Identity=32.3353293413174, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786891, Length=208, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.55 [H]

Molecular weight: Translated: 33596; Mature: 33465

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVKECRVMAKQRSVVAGVDMGATHIRFCLQTAAGEIVHCEKRRTADVLVPDVASGIAAM
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEECHHHHHHHHHH
LHQQFVHYDVTCCGLIMGLPALVGKDQRSIISTPNLPLSAGELHGLADNLQASLKCPLAF
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHCCHHHHHHHEECCEEE
SRDVNLQLSWDVQENHLVDQLVLGAYLGTGMGFAIWMNGAPWTGAHGVAGELGHIPQGDM
CCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
TQHCGCGNSGCLETVCSGLALKRWYEQQPRNYTLSELFVHASDELFVQSLLDHAARAIAS
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
SVNLFDPDVVILGGGVMDMVAFPREALIDKIKCYLRRPLPYQEVCFIPASSSAFNGAQGA
HCCCCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCC
ATLASGRFFAKQ
HHHHCCCEECCC
>Mature Secondary Structure 
PVKECRVMAKQRSVVAGVDMGATHIRFCLQTAAGEIVHCEKRRTADVLVPDVASGIAAM
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCEECHHHHHHHHHH
LHQQFVHYDVTCCGLIMGLPALVGKDQRSIISTPNLPLSAGELHGLADNLQASLKCPLAF
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHCCHHHHHHHEECCEEE
SRDVNLQLSWDVQENHLVDQLVLGAYLGTGMGFAIWMNGAPWTGAHGVAGELGHIPQGDM
CCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
TQHCGCGNSGCLETVCSGLALKRWYEQQPRNYTLSELFVHASDELFVQSLLDHAARAIAS
HHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHH
SVNLFDPDVVILGGGVMDMVAFPREALIDKIKCYLRRPLPYQEVCFIPASSSAFNGAQGA
HCCCCCCCEEEECCCHHHHHHCCHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCCCCCC
ATLASGRFFAKQ
HHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9401019 [H]