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The map label for this gene is lldR [H]

Identifier: 218550882

GI number: 218550882

Start: 3688580

End: 3689356

Strand: Direct

Name: lldR [H]

Synonym: EFER_3598

Alternate gene names: 218550882

Gene position: 3688580-3689356 (Clockwise)

Preceding gene: 218550881

Following gene: 218550883

Centisome position: 80.38

GC content: 54.18

Gene sequence:

>777_bases
ATGATTGTTATACCCAGACGCCTGTCAGACGAGGTCGCCTCTCGTGTGCGAGCGCTGATTGAAGAGCAGCAACTGGAAGC
GGGTATGAAATTACCCGCCGAACGCCAGTTAGCGGCACAACTGGGTGTCTCGCGCAATTCCCTGCGCGAGGCGCTGGCTA
AGTTGATTAGCGAAGGGGTGTTGCTTAGCCGTCGTGGTGGCGGCACGTTTGTTCGCTGGCAACATGAAGCGTGGTCTGAA
CAAAATATCGTCCAACCGCTGAAAAGCCTGATGGCAGATGATCCCGATTATGGCTTTGATATTCTGGAAGCCCGTCACGC
CATTGAAGCCAGCACCGCATGGCATGCGGCAATGCGTGCCACAACTGCCGATAAAGAGAAAATCAAACTCTGCTTTGACG
CAACGCTCAGCGAAGACCCGGATCTCGCCTCCCAGGCCGACGTTCGCTTTCATCTGGCGATTGCTGAAGCCTCACACAAC
GTGGTGCTTTTACAAACCATGCGCGGCTTCTTCGATGTGCTGCACTCATCGGTAAAACAGAGTCGCCAGCGTATGTACCT
TGTTCCGCCCGTATTTTCACAACTCACGGAGCAACACCAGGCGGTGATGGAAGCCATTTTTGCTGGCGATGCCGATGGCG
CGCGTAAAGCAATGATGGCGCACCTTAGTTTTGTCCACACCACCATTAAACGATTTGATGAAGACCAGGCCCGCCAGGCA
CGTATTACCCGTCTGCCCGGTGACCAGAATGATATTTCCAGGGAGAACGAAGCATGA

Upstream 100 bases:

>100_bases
ACCTGTTCCGCTTTACCGTCAAACACAGCCTGATATTCACCTGCATGGTCGGCGTGATCACCACGCTTCAGGCCTATGTT
TTAACCTGGATGATCCCGTA

Downstream 100 bases:

>100_bases
TTATTTCAGCAGCCAGCGATTATCGCGCCGCAGCGCAACGCATTTTGCCCCCTTTCTTATTCCACTACATCGACGGTGGC
GCTTATGCGGAATACACCTT

Product: DNA-binding transcriptional repressor LldR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MIVIPRRLSDEVASRVRALIEEQQLEAGMKLPAERQLAAQLGVSRNSLREALAKLISEGVLLSRRGGGTFVRWQHEAWSE
QNIVQPLKSLMADDPDYGFDILEARHAIEASTAWHAAMRATTADKEKIKLCFDATLSEDPDLASQADVRFHLAIAEASHN
VVLLQTMRGFFDVLHSSVKQSRQRMYLVPPVFSQLTEQHQAVMEAIFAGDADGARKAMMAHLSFVHTTIKRFDEDQARQA
RITRLPGDQNDISRENEA

Sequences:

>Translated_258_residues
MIVIPRRLSDEVASRVRALIEEQQLEAGMKLPAERQLAAQLGVSRNSLREALAKLISEGVLLSRRGGGTFVRWQHEAWSE
QNIVQPLKSLMADDPDYGFDILEARHAIEASTAWHAAMRATTADKEKIKLCFDATLSEDPDLASQADVRFHLAIAEASHN
VVLLQTMRGFFDVLHSSVKQSRQRMYLVPPVFSQLTEQHQAVMEAIFAGDADGARKAMMAHLSFVHTTIKRFDEDQARQA
RITRLPGDQNDISRENEA
>Mature_258_residues
MIVIPRRLSDEVASRVRALIEEQQLEAGMKLPAERQLAAQLGVSRNSLREALAKLISEGVLLSRRGGGTFVRWQHEAWSE
QNIVQPLKSLMADDPDYGFDILEARHAIEASTAWHAAMRATTADKEKIKLCFDATLSEDPDLASQADVRFHLAIAEASHN
VVLLQTMRGFFDVLHSSVKQSRQRMYLVPPVFSQLTEQHQAVMEAIFAGDADGARKAMMAHLSFVHTTIKRFDEDQARQA
RITRLPGDQNDISRENEA

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=258, Percent_Identity=87.5968992248062, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1786303, Length=231, Percent_Identity=40.6926406926407, Blast_Score=154, Evalue=8e-39,
Organism=Escherichia coli, GI1789353, Length=230, Percent_Identity=32.6086956521739, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790780, Length=244, Percent_Identity=31.9672131147541, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082208, Length=238, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994955, Length=214, Percent_Identity=27.5700934579439, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28927; Mature: 28927

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVIPRRLSDEVASRVRALIEEQQLEAGMKLPAERQLAAQLGVSRNSLREALAKLISEGV
CEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCC
LLSRRGGGTFVRWQHEAWSEQNIVQPLKSLMADDPDYGFDILEARHAIEASTAWHAAMRA
EEEECCCCCEEEEEHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TTADKEKIKLCFDATLSEDPDLASQADVRFHLAIAEASHNVVLLQTMRGFFDVLHSSVKQ
HCCCHHHHHHHEECCCCCCCCCCCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHH
SRQRMYLVPPVFSQLTEQHQAVMEAIFAGDADGARKAMMAHLSFVHTTIKRFDEDQARQA
HHHCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RITRLPGDQNDISRENEA
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIVIPRRLSDEVASRVRALIEEQQLEAGMKLPAERQLAAQLGVSRNSLREALAKLISEGV
CEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCC
LLSRRGGGTFVRWQHEAWSEQNIVQPLKSLMADDPDYGFDILEARHAIEASTAWHAAMRA
EEEECCCCCEEEEEHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TTADKEKIKLCFDATLSEDPDLASQADVRFHLAIAEASHNVVLLQTMRGFFDVLHSSVKQ
HCCCHHHHHHHEECCCCCCCCCCCCCCEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHH
SRQRMYLVPPVFSQLTEQHQAVMEAIFAGDADGARKAMMAHLSFVHTTIKRFDEDQARQA
HHHCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHH
RITRLPGDQNDISRENEA
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]