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The map label for this gene is kdgR [H]

Identifier: 218550834

GI number: 218550834

Start: 3632309

End: 3633385

Strand: Direct

Name: kdgR [H]

Synonym: EFER_3550

Alternate gene names: 218550834

Gene position: 3632309-3633385 (Clockwise)

Preceding gene: 218550833

Following gene: 218550835

Centisome position: 79.16

GC content: 51.25

Gene sequence:

>1077_bases
TTGCCAGCGCTAATTTTCGCGTTAAGGTGTTCTCACTTTCAGGCAAGGAATCCCCCTATGGCAGCAAAATCAACGCGCCC
CACCATTAGCGATGTCGCAAAAGCCGCAAAAACCGGCAAAACCAGCATCTCTCGTTACCTCAACGGCGAAAAACATCTGC
TTTCCGAAGCATTGCTGGCGCGGATTGAAAAAGCGATTGCCGATCTTGATTATCGCCCCAGCCTGATGGCCCGAAGCCTG
AAACGTGGCCGTACCCGGCTGATTGGTCTGATTATCGCCGATATTACTAACCCCTACTCGGTAAATGTGTTAAGTGGCAT
TGAGGCGGCTTGTCGCGATAAAGGATTCACTCCCCTGGTGTGTAATACCAACAATGAAGTGAATCAGGAACAACATTATC
TCGATTTGCTACGCAGCTACCAGGTGGAAGGTATTGTGGTCAATGCCGTAGGAATGCGTGAAGAAGGGCTAAATCGTTTG
CAACAGTCGGCACTGCCAATGGTGCTTATTGATCGCAAGATCCCCGATTTTGCCTGTGATGTTGTTGGACTGGACAACAC
GCAAGCTGCAACTACCGCTACCGAGCATTTAATTGAGCAAGGGTTTGAAGCCATACTCTTTCTCAGCGAACCGCTGGGAA
TGGTAAACACGCGACGTGAAAGGCTAAATGCTTTTCACGCTACTCTGGCACGTTATCCGGGTGTTGTAGCGCAGAATGCA
GAAGTTCCACTGGCTGAGAATACACTTCTGGAAAACACGCTTCGCCAGTTCCACCAGCAACATCGGGGAATGCGCAAAGC
CGTGATGTCGGCAAACGGCGCACTAACGCTACAGGTAGCACGCGCGCTCAAACGTATTGGCCTGAACTGGGGCAGTGATA
TCGGCCTGCTTGGTTTTGATGAGCTGGAATGGGCCGAACTGGCAGGCGTGGGGATTACCACGCTCAAACAACCGACCTGG
CAAATTGGTTATGCGGCTGTGGAACAGGTGGTACGCCGTATTGAAGGTGTTACAGAGCCTATTCGTGAGCACGTTTTCTC
CGGCGAGTTGATTGTTCGCGGATCAACGGCACGTTAA

Upstream 100 bases:

>100_bases
CGCAGAAGGTAAAGCACAAAACCGTCGCGTAGAAATTACCTTAAGCCCGCTGTAATTCCCCAATGTCGGATGGCGGTTTC
GTCATCCGACATTTATCATC

Downstream 100 bases:

>100_bases
ATTCCTTCGTGATAGCGATCATAATTTCAACACAGCGCCCTTTTCTTTGGAACCGGTTCCAACTAGCGTTATATCAATCG
CGCTAGCCAGGGAGTTCCCA

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Kdg operon repressor [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MPALIFALRCSHFQARNPPMAAKSTRPTISDVAKAAKTGKTSISRYLNGEKHLLSEALLARIEKAIADLDYRPSLMARSL
KRGRTRLIGLIIADITNPYSVNVLSGIEAACRDKGFTPLVCNTNNEVNQEQHYLDLLRSYQVEGIVVNAVGMREEGLNRL
QQSALPMVLIDRKIPDFACDVVGLDNTQAATTATEHLIEQGFEAILFLSEPLGMVNTRRERLNAFHATLARYPGVVAQNA
EVPLAENTLLENTLRQFHQQHRGMRKAVMSANGALTLQVARALKRIGLNWGSDIGLLGFDELEWAELAGVGITTLKQPTW
QIGYAAVEQVVRRIEGVTEPIREHVFSGELIVRGSTAR

Sequences:

>Translated_358_residues
MPALIFALRCSHFQARNPPMAAKSTRPTISDVAKAAKTGKTSISRYLNGEKHLLSEALLARIEKAIADLDYRPSLMARSL
KRGRTRLIGLIIADITNPYSVNVLSGIEAACRDKGFTPLVCNTNNEVNQEQHYLDLLRSYQVEGIVVNAVGMREEGLNRL
QQSALPMVLIDRKIPDFACDVVGLDNTQAATTATEHLIEQGFEAILFLSEPLGMVNTRRERLNAFHATLARYPGVVAQNA
EVPLAENTLLENTLRQFHQQHRGMRKAVMSANGALTLQVARALKRIGLNWGSDIGLLGFDELEWAELAGVGITTLKQPTW
QIGYAAVEQVVRRIEGVTEPIREHVFSGELIVRGSTAR
>Mature_357_residues
PALIFALRCSHFQARNPPMAAKSTRPTISDVAKAAKTGKTSISRYLNGEKHLLSEALLARIEKAIADLDYRPSLMARSLK
RGRTRLIGLIIADITNPYSVNVLSGIEAACRDKGFTPLVCNTNNEVNQEQHYLDLLRSYQVEGIVVNAVGMREEGLNRLQ
QSALPMVLIDRKIPDFACDVVGLDNTQAATTATEHLIEQGFEAILFLSEPLGMVNTRRERLNAFHATLARYPGVVAQNAE
VPLAENTLLENTLRQFHQQHRGMRKAVMSANGALTLQVARALKRIGLNWGSDIGLLGFDELEWAELAGVGITTLKQPTWQ
IGYAAVEQVVRRIEGVTEPIREHVFSGELIVRGSTAR

Specific function: Transcriptional repressor of the kdg operon for pectin utilization [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790194, Length=338, Percent_Identity=27.810650887574, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790369, Length=350, Percent_Identity=27.7142857142857, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1788474, Length=335, Percent_Identity=24.4776119402985, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1787948, Length=316, Percent_Identity=28.1645569620253, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1789202, Length=332, Percent_Identity=25.9036144578313, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=25, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787906, Length=236, Percent_Identity=28.8135593220339, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787580, Length=322, Percent_Identity=23.9130434782609, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789068, Length=339, Percent_Identity=22.1238938053097, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786540, Length=323, Percent_Identity=23.5294117647059, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786268, Length=184, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790715, Length=324, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790689, Length=203, Percent_Identity=25.615763546798, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 39514; Mature: 39383

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALIFALRCSHFQARNPPMAAKSTRPTISDVAKAAKTGKTSISRYLNGEKHLLSEALLA
CCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHH
RIEKAIADLDYRPSLMARSLKRGRTRLIGLIIADITNPYSVNVLSGIEAACRDKGFTPLV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEE
CNTNNEVNQEQHYLDLLRSYQVEGIVVNAVGMREEGLNRLQQSALPMVLIDRKIPDFACD
ECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCHHHC
VVGLDNTQAATTATEHLIEQGFEAILFLSEPLGMVNTRRERLNAFHATLARYPGVVAQNA
EECCCCCCHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCC
EVPLAENTLLENTLRQFHQQHRGMRKAVMSANGALTLQVARALKRIGLNWGSDIGLLGFD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
ELEWAELAGVGITTLKQPTWQIGYAAVEQVVRRIEGVTEPIREHVFSGELIVRGSTAR
CCHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
>Mature Secondary Structure 
PALIFALRCSHFQARNPPMAAKSTRPTISDVAKAAKTGKTSISRYLNGEKHLLSEALLA
CHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHH
RIEKAIADLDYRPSLMARSLKRGRTRLIGLIIADITNPYSVNVLSGIEAACRDKGFTPLV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCCEEE
CNTNNEVNQEQHYLDLLRSYQVEGIVVNAVGMREEGLNRLQQSALPMVLIDRKIPDFACD
ECCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEECCCCCCHHHC
VVGLDNTQAATTATEHLIEQGFEAILFLSEPLGMVNTRRERLNAFHATLARYPGVVAQNA
EECCCCCCHHHHHHHHHHHCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCC
EVPLAENTLLENTLRQFHQQHRGMRKAVMSANGALTLQVARALKRIGLNWGSDIGLLGFD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
ELEWAELAGVGITTLKQPTWQIGYAAVEQVVRRIEGVTEPIREHVFSGELIVRGSTAR
CCHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]