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The map label for this gene is yrbG [H]

Identifier: 218550479

GI number: 218550479

Start: 3259666

End: 3260679

Strand: Direct

Name: yrbG [H]

Synonym: EFER_3173

Alternate gene names: 218550479

Gene position: 3259666-3260679 (Clockwise)

Preceding gene: 218550471

Following gene: 218550480

Centisome position: 71.04

GC content: 49.11

Gene sequence:

>1014_bases
GTGGAGCGGCGAGTATACCTGAAGAAAGGATTTTTGATGCTTTTAGCTACGGCGCTGTTAATTATTGGTTTACTTCTGGT
GGTTTACGGTGCCGACCGTTTAGTGTTTGCTGCCTCAATAATCTGCAGAACATTGGGTGTTCCCCCGCTGATTATTGGTA
TGACTGTTGTCAGCATCGGTACTTCATTGCCGGAAATTATCGTCTCTCTCGCGGCATCGCTGCATGGTCAACTGGATTTA
GCTGTTGGTACTGCTTTGGGTTCAAATATTACCAACATCTTACTCATTTTAGGTCTTGCTGCGCTCATTCGCCCCTTTAC
CGTCCATTCTGATGTTCTGCGGCGCGAGCTACCATTAATGTTACTCATAGCGGTCGTAGCCGGTTCCGTACTCTATGACG
GACAACTAAAACGCAGCGATGGTATCTTTCTTTTACTTCTGGCCGTGCTATGGCTGCTGTTCATTGTTAAAATCGCGCGT
CTGGCTGAACGTCAGGGCAACGACAGTCTCACCAGAGAGCAACTGGCTGAATTACCGCGTGAAGGTGGCTTACCGGTCGC
ATTTTTATGGCTGGGGATTGCGCTGATTATTATGCCTGTCGCCACCAGAATGGTGGTTGATAATGCCACTGTGCTGGCAA
ACTATTTTGCTATTAGTGAAATGACCATCGGATTAACGGTGATCGCGATTGGTACCAGCCTGCCTGAGCTGGCAACAGCG
ATCGCAGGTGTGCGCAAAGGTGAAAATGATATTGCCGTAGGAAATATCATCGGCGCAAACATATTTAATATCGTCATCGT
ACTGGCTCTGCCAGCAGTGATAACCCCCGGCGAAATTCATCCACTGGCCTGGGTTCGTGACTATAGCGTAATGCTGGTAG
TCAGCATTATATTCGCGTTACTTTGCTGGCGGCGTCCGCAGCAAATTGGTCGCAGTGTCGGTGTGCTGTTGACCGGTGGT
TTTGTTTTGTGGCTGGCGATGCTGCACTGGCTTTCGCCCCTTCTCGTTGAATGA

Upstream 100 bases:

>100_bases
TTATTACCCGCCCTGGTTAGCGAAAGCTGGCATTTGTTTTACTTTTTAGCCGCATAAAGTCAAAATTAAGAATTCGTCAC
GGCTTCCAACACTCCTTCCA

Downstream 100 bases:

>100_bases
CTGGAAACGCATTATGTCGCATTTAGAGTTACAACCGGGTTTTGACTTTCAGAAAGCAGGCAAAGAAGTCCTGGCGATTG
AACGTGAAGGCCTGGCCGAT

Product: calcium/sodium:proton antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MERRVYLKKGFLMLLATALLIIGLLLVVYGADRLVFAASIICRTLGVPPLIIGMTVVSIGTSLPEIIVSLAASLHGQLDL
AVGTALGSNITNILLILGLAALIRPFTVHSDVLRRELPLMLLIAVVAGSVLYDGQLKRSDGIFLLLLAVLWLLFIVKIAR
LAERQGNDSLTREQLAELPREGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISEMTIGLTVIAIGTSLPELATA
IAGVRKGENDIAVGNIIGANIFNIVIVLALPAVITPGEIHPLAWVRDYSVMLVVSIIFALLCWRRPQQIGRSVGVLLTGG
FVLWLAMLHWLSPLLVE

Sequences:

>Translated_337_residues
MERRVYLKKGFLMLLATALLIIGLLLVVYGADRLVFAASIICRTLGVPPLIIGMTVVSIGTSLPEIIVSLAASLHGQLDL
AVGTALGSNITNILLILGLAALIRPFTVHSDVLRRELPLMLLIAVVAGSVLYDGQLKRSDGIFLLLLAVLWLLFIVKIAR
LAERQGNDSLTREQLAELPREGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISEMTIGLTVIAIGTSLPELATA
IAGVRKGENDIAVGNIIGANIFNIVIVLALPAVITPGEIHPLAWVRDYSVMLVVSIIFALLCWRRPQQIGRSVGVLLTGG
FVLWLAMLHWLSPLLVE
>Mature_337_residues
MERRVYLKKGFLMLLATALLIIGLLLVVYGADRLVFAASIICRTLGVPPLIIGMTVVSIGTSLPEIIVSLAASLHGQLDL
AVGTALGSNITNILLILGLAALIRPFTVHSDVLRRELPLMLLIAVVAGSVLYDGQLKRSDGIFLLLLAVLWLLFIVKIAR
LAERQGNDSLTREQLAELPREGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISEMTIGLTVIAIGTSLPELATA
IAGVRKGENDIAVGNIIGANIFNIVIVLALPAVITPGEIHPLAWVRDYSVMLVVSIIFALLCWRRPQQIGRSVGVLLTGG
FVLWLAMLHWLSPLLVE

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=325, Percent_Identity=89.2307692307692, Blast_Score=499, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 36249; Mature: 36249

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRVYLKKGFLMLLATALLIIGLLLVVYGADRLVFAASIICRTLGVPPLIIGMTVVSIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
TSLPEIIVSLAASLHGQLDLAVGTALGSNITNILLILGLAALIRPFTVHSDVLRRELPLM
CHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIAVVAGSVLYDGQLKRSDGIFLLLLAVLWLLFIVKIARLAERQGNDSLTREQLAELPR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
EGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISEMTIGLTVIAIGTSLPELATA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHH
IAGVRKGENDIAVGNIIGANIFNIVIVLALPAVITPGEIHPLAWVRDYSVMLVVSIIFAL
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LCWRRPQQIGRSVGVLLTGGFVLWLAMLHWLSPLLVE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERRVYLKKGFLMLLATALLIIGLLLVVYGADRLVFAASIICRTLGVPPLIIGMTVVSIG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
TSLPEIIVSLAASLHGQLDLAVGTALGSNITNILLILGLAALIRPFTVHSDVLRRELPLM
CHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLIAVVAGSVLYDGQLKRSDGIFLLLLAVLWLLFIVKIARLAERQGNDSLTREQLAELPR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
EGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISEMTIGLTVIAIGTSLPELATA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHH
IAGVRKGENDIAVGNIIGANIFNIVIVLALPAVITPGEIHPLAWVRDYSVMLVVSIIFAL
HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
LCWRRPQQIGRSVGVLLTGGFVLWLAMLHWLSPLLVE
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]