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The map label for this gene is tsr [H]

Identifier: 218550363

GI number: 218550363

Start: 3128702

End: 3130513

Strand: Reverse

Name: tsr [H]

Synonym: EFER_3055

Alternate gene names: 218550363

Gene position: 3130513-3128702 (Counterclockwise)

Preceding gene: 218550365

Following gene: 218550358

Centisome position: 68.22

GC content: 51.66

Gene sequence:

>1812_bases
TTGTACCATAAACAGCCGCGACAGAGTGTGACATCGCTAAAAACGCAGGCTGACAGCGATAAAATCCGCCTTTTGAACGT
GCCAAAACATAAAGTTTTTTCGTCTCAGGCCGACAACCAGAGTATCTGTCTAGTGGAACGAGAAAATATGTTAAAACGTA
TCAAAATTGTCACCAGCTTACTGTTGGTACTTGCCATTTTTGGCCTTTTACAACTGACATCGGGTGGTCTGTTCTTTAGT
GCACTTAAGAACGACAAAGAGAACTTTACCGTTTTGCAGACGATTCGCCAGCAACAGTCAACGTTGAATGGCAGCTGGGT
CGCACTGCTGCAAACGCGAAATACCCTTAACCGGGCGGGCATTCGCTACATGATGGATCAGAACAATATTGGTAGCGGTG
CTACGGTGACTGAACTGATGCAGTTGGCGAGCATTTCTTTAAAGCAGGCGGAAAAAAACTGGGCCGAATACGAAGCTCTG
CCGCTCGATCCCCGTCAGAGCGAAACGGCAGCTATTGAAATTAAACGAAATTACGATATCTACCACAATGCGCTGGCGGA
ACTGATTCAGCTGCTGGGGGCGGGCAAGATTAACGAATTTTTTGATCAGCCGACTCAGAGCTATCAGAACGGTTTCGAAA
AACAGTATATCGAATGGATGCAGCAAAACGATCGCCTGTATGACATTGCCGTAGAGGATAATGACAGCTCTTACAGCCAT
GCAATGTTGCTGCTGGCGGGAATTTTGATTGCTGTTCTGGCTGTTATTGTTGCCGTCTGGTTTGGTATTAAACACTCACT
GGTTGAGCCGATGAACCGCCTGGTGGACAGCATTCGCCATATTGCCGGGGGGGATCTGGTAAAACCCATCGATGTGGATG
GCGATAATGAAGTGGGGCAACTGGCAGATAGCCTGCGTCATATGCAGAGCGAACTGGTGCGTACCGTCGGTGATGTGCGC
AACGGGGCAGATGCCATTTACAGCGGGGCAAGTGAGATTGCCATGGGCAACAATGATCTCTCTTCTCGTACTGAGCAGCA
GGCCGCTTCGCTGGAAGAAACCGCAGCCAGCATGGAACAACTGACCGCGACGGTTAAACAGAACGCTGAAAACGCGCGTC
AGGCCAGTCATCTGGCGTTGAGTGCTTCAGAAACAGCACAACGTGGCGGGAAAGTGGTGGATAACGTGGTACAAACCATG
CGTGATATCTCCACCAGTTCGCAGAAAATCGCCGATATTATCAGCGTAATTGACGGTATTGCTTTCCAGACCAATATCCT
GGCGCTGAATGCGGCAGTTGAAGCGGCGCGTGCCGGTGAGCAAGGCCGTGGATTTGCCGTCGTTGCCGGAGAAGTTCGCA
CCCTTGCAAGCCGTAGTGCTCAGGCGGCGCGGGAAATTAAAAGCCTGATTGAAGATTCCGTTAGCCGGGTAGATACGGGA
TCGACTCTGGTTGAAAGTGCCGGGGAAACAATGGCTGAGATCGTCAATGCCGTGACCCGTGTGACCGATATCATGGGTGA
AATTGCCTCGGCCTCTGATGAGCAGAGTCGTGGTATTGATCAGGTAGGGCTGGCTGTTGCTGAGATGGATCGCGTAACTC
AGCAGAACGCCGCGCTGGTGGAAGAATCTGCCGCCGCCGCCGCCGCGCTGGAAGAACAAGCCAGCCGCCTGAACGAAGCC
GTAGCGGTATTTCGCATCCACCATGAGCAACAACGCGCACGTGAAAGTGCAGTGGTGAAAACCGTTACCGCACCAGCGGC
TCCCCGCAAAGCTGCCGTGGCAGATAACAGCGATAACTGGGAAACGTTTTAA

Upstream 100 bases:

>100_bases
TTTCAGTGGCGGTTAACGCCATAAACCGTTCGGTAATACAGGAGATGATATCGATGCTATAAGCCATGGGAGTATCACTG
ATTCGAAGACAATTGGTACT

Downstream 100 bases:

>100_bases
GTAAGGAATACATTCGCTAAGATTGGTAACAAAGTACGCTTTTTGGCCTTGAAAATTATGTAAATTCAATATCTTGTATG
AAAATCAGGTCGGATAAGCG

Product: methyl-accepting chemotaxis protein I, serine sensor receptor

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MYHKQPRQSVTSLKTQADSDKIRLLNVPKHKVFSSQADNQSICLVERENMLKRIKIVTSLLLVLAIFGLLQLTSGGLFFS
ALKNDKENFTVLQTIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGATVTELMQLASISLKQAEKNWAEYEAL
PLDPRQSETAAIEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQSYQNGFEKQYIEWMQQNDRLYDIAVEDNDSSYSH
AMLLLAGILIAVLAVIVAVWFGIKHSLVEPMNRLVDSIRHIAGGDLVKPIDVDGDNEVGQLADSLRHMQSELVRTVGDVR
NGADAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTM
RDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAREIKSLIEDSVSRVDTG
STLVESAGETMAEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLNEA
VAVFRIHHEQQRARESAVVKTVTAPAAPRKAAVADNSDNWETF

Sequences:

>Translated_603_residues
MYHKQPRQSVTSLKTQADSDKIRLLNVPKHKVFSSQADNQSICLVERENMLKRIKIVTSLLLVLAIFGLLQLTSGGLFFS
ALKNDKENFTVLQTIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGATVTELMQLASISLKQAEKNWAEYEAL
PLDPRQSETAAIEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQSYQNGFEKQYIEWMQQNDRLYDIAVEDNDSSYSH
AMLLLAGILIAVLAVIVAVWFGIKHSLVEPMNRLVDSIRHIAGGDLVKPIDVDGDNEVGQLADSLRHMQSELVRTVGDVR
NGADAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTM
RDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAREIKSLIEDSVSRVDTG
STLVESAGETMAEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLNEA
VAVFRIHHEQQRARESAVVKTVTAPAAPRKAAVADNSDNWETF
>Mature_603_residues
MYHKQPRQSVTSLKTQADSDKIRLLNVPKHKVFSSQADNQSICLVERENMLKRIKIVTSLLLVLAIFGLLQLTSGGLFFS
ALKNDKENFTVLQTIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGATVTELMQLASISLKQAEKNWAEYEAL
PLDPRQSETAAIEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQSYQNGFEKQYIEWMQQNDRLYDIAVEDNDSSYSH
AMLLLAGILIAVLAVIVAVWFGIKHSLVEPMNRLVDSIRHIAGGDLVKPIDVDGDNEVGQLADSLRHMQSELVRTVGDVR
NGADAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTM
RDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAREIKSLIEDSVSRVDTG
STLVESAGETMAEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLNEA
VAVFRIHHEQQRARESAVVKTVTAPAAPRKAAVADNSDNWETF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=554, Percent_Identity=89.3501805054152, Blast_Score=954, Evalue=0.0,
Organism=Escherichia coli, GI1788195, Length=556, Percent_Identity=58.273381294964, Blast_Score=567, Evalue=1e-163,
Organism=Escherichia coli, GI1788194, Length=534, Percent_Identity=47.3782771535581, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1787690, Length=426, Percent_Identity=48.5915492957746, Blast_Score=367, Evalue=1e-102,
Organism=Escherichia coli, GI1789453, Length=324, Percent_Identity=41.6666666666667, Blast_Score=223, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 65637; Mature: 65637

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50885 HAMP ; PS00538 CHEMOTAXIS_TRANSDUC_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYHKQPRQSVTSLKTQADSDKIRLLNVPKHKVFSSQADNQSICLVERENMLKRIKIVTSL
CCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHH
LLVLAIFGLLQLTSGGLFFSALKNDKENFTVLQTIRQQQSTLNGSWVALLQTRNTLNRAG
HHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHC
IRYMMDQNNIGSGATVTELMQLASISLKQAEKNWAEYEALPLDPRQSETAAIEIKRNYDI
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCH
YHNALAELIQLLGAGKINEFFDQPTQSYQNGFEKQYIEWMQQNDRLYDIAVEDNDSSYSH
HHHHHHHHHHHHCCCCHHHHHCCHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCHHHH
AMLLLAGILIAVLAVIVAVWFGIKHSLVEPMNRLVDSIRHIAGGDLVKPIDVDGDNEVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LADSLRHMQSELVRTVGDVRNGADAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAREIKSLIEDSVSRVDTG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
STLVESAGETMAEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
EESAAAAAALEEQASRLNEAVAVFRIHHEQQRARESAVVKTVTAPAAPRKAAVADNSDNW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ETF
CCC
>Mature Secondary Structure
MYHKQPRQSVTSLKTQADSDKIRLLNVPKHKVFSSQADNQSICLVERENMLKRIKIVTSL
CCCCCHHHHHHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHH
LLVLAIFGLLQLTSGGLFFSALKNDKENFTVLQTIRQQQSTLNGSWVALLQTRNTLNRAG
HHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHC
IRYMMDQNNIGSGATVTELMQLASISLKQAEKNWAEYEALPLDPRQSETAAIEIKRNYDI
CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCH
YHNALAELIQLLGAGKINEFFDQPTQSYQNGFEKQYIEWMQQNDRLYDIAVEDNDSSYSH
HHHHHHHHHHHHCCCCHHHHHCCHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCHHHH
AMLLLAGILIAVLAVIVAVWFGIKHSLVEPMNRLVDSIRHIAGGDLVKPIDVDGDNEVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LADSLRHMQSELVRTVGDVRNGADAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
LTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAREIKSLIEDSVSRVDTG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
STLVESAGETMAEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHH
EESAAAAAALEEQASRLNEAVAVFRIHHEQQRARESAVVKTVTAPAAPRKAAVADNSDNW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
ETF
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]