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The map label for this gene is grdB [H]

Identifier: 218550321

GI number: 218550321

Start: 3083673

End: 3083897

Strand: Reverse

Name: grdB [H]

Synonym: EFER_3013

Alternate gene names: 218550321

Gene position: 3083897-3083673 (Counterclockwise)

Preceding gene: 218550322

Following gene: 218550320

Centisome position: 67.21

GC content: 49.78

Gene sequence:

>225_bases
ATGGTCAAAGAGATTGAAAAAGTCATGCCGGTAGTCCATATCGCAACGGTTGTTCCGATATCACTCACGGTTGGCGCTAA
CCGTATTGTGCCTGCTGTGGCTATCCCACATCCACTGGGTAACCCACTGCTTGATGGCAGCGACGAACAAAAACTTCGTC
GTCAGCTTGTGGAGAAGGCACTTGCGGCATTACAGACACCGGTAACTGAACAGACGGTGTTTTAA

Upstream 100 bases:

>100_bases
TAAGTACGGCGCTGATATTGCCATGAAACTGCAGAAAGCGGGAGTAAGCGCAGCCATTCTGACGTCGACATGAGGCACTT
GCACTCGTTGCGGCGCAACG

Downstream 100 bases:

>100_bases
CCAGATCGCCAGCCGTAAGGCTGGCGATACTGACAGCAGGATGCAATGGAAACGTTATTAATCATTACCAATAATCCGGC
CGTAGAAGCGCATTATCTCG

Product: glycine reductase complex component B subunit gamma

Products: NA

Alternate protein names: Selenoprotein PB gamma [H]

Number of amino acids: Translated: 74; Mature: 74

Protein sequence:

>74_residues
MVKEIEKVMPVVHIATVVPISLTVGANRIVPAVAIPHPLGNPLLDGSDEQKLRRQLVEKALAALQTPVTEQTVF

Sequences:

>Translated_74_residues
MVKEIEKVMPVVHIATVVPISLTVGANRIVPAVAIPHPLGNPLLDGSDEQKLRRQLVEKALAALQTPVTEQTVF
>Mature_74_residues
MVKEIEKVMPVVHIATVVPISLTVGANRIVPAVAIPHPLGNPLLDGSDEQKLRRQLVEKALAALQTPVTEQTVF

Specific function: In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate. Then the PB- activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated seleno

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdB/grdF/grdH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023193
- InterPro:   IPR010186
- InterPro:   IPR022787
- InterPro:   IPR010187 [H]

Pfam domain/function: PF07355 GRDB [H]

EC number: =1.21.4.2 [H]

Molecular weight: Translated: 7989; Mature: 7989

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKEIEKVMPVVHIATVVPISLTVGANRIVPAVAIPHPLGNPLLDGSDEQKLRRQLVEKA
CCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHH
LAALQTPVTEQTVF
HHHHHCCCCCCCCC
>Mature Secondary Structure
MVKEIEKVMPVVHIATVVPISLTVGANRIVPAVAIPHPLGNPLLDGSDEQKLRRQLVEKA
CCCHHHHHHHHHHHHHHHHHHEECCCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHH
LAALQTPVTEQTVF
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10091582; 8529639 [H]