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The map label for this gene is int [H]

Identifier: 218550118

GI number: 218550118

Start: 2872100

End: 2873269

Strand: Reverse

Name: int [H]

Synonym: EFER_2806

Alternate gene names: 218550118

Gene position: 2873269-2872100 (Counterclockwise)

Preceding gene: 218550119

Following gene: 218550115

Centisome position: 62.62

GC content: 47.44

Gene sequence:

>1170_bases
ATGAAGCTGACTGCTCGTCAGGTTGAAACTGCAAAACCTAAAGATAAGCCCTACAAACTCGCTGATGGTGGTGGTCTTTA
CCTGCTGGTTAATCCCAATGGCAAAAGATACTGGCGTCTCAAATACCGTTCACTAGGCAAAGAGAAGCTGCTCGCTATTG
GCGTTTACCCTGATGTTTCTTTAGCTGAAGCCAGAAGTAAGCGTGAGGATGCTAAAAGAACATTAGCTGTTGGCAATGAT
CCTTCTCTTGAACGAAAAATTGAGAAACTTAGCCGTCAACAGGACGCAGAAAACTCGTTTGAGGCTATCACGCGGGAGTG
GTATCAGCGTCGCTATGACCGCTGGTCTGTCTCCTACCGCGAAGAGATGCTAAGAACCTTTGAAAAGGATGTATTTCCTT
ATATCGGTCACCGGCCAATCAAAGATATCAAGCCGATGGAGCTGCTTGCTGTTCTTTCAAAGATAGAAGCACGAGGAGCA
ACTGAGAAGGTACGTAAGGTTCGTCAACGTTGTGGAGAAGTCTGGAAGTATGCCGTTGTGACTGGCAGAGCCGAGTACAA
TCCAGCACCTGATCTAGCCAGCGCCGTGACTCCACATGAGAAAGAACACTATGCTTTTTTAACCCAGGATGAATTACCAG
AGTTTCTTCGGACTCTGAATACCTATGCCGGTAGTGTGCTTGTTAAGATTGCGATGCAATTACTTATTTTGACTGGAGTA
AGGCCTGGGGAATTGAGGCAAGCGGAGTGGCAGGAGTTTGATTTTGAGCGGAAGGTTTGGAACGTGCCAGCAGAGCGCAT
GAAAATGCGCCGCCCTCATCTGGTTCCGTTATCAAGCCAGGCAATTGACCTACTTAATCAGCTTAAACCTATGACAGGTG
CAGGTGCGTTGCTGTTCCCTGGGCGTAATAATCCTAAGAAATCGATGAGTGATATGGCATTGATTGTGTTGGTTAGGCGT
ATCGGCTATGCCGGGCGCGTTACGGGGCACGGATTCCGCCACACGATGAGTACTATTTTGCATGAGCAGGGATTTAACTC
GGCCTGGATTGAGTTACAGCTGGCTCACGTCGATAAGAACTCAATTCGTGGGACATATAACCATGCTCAATATCTGGAGG
GGCGGAGGGAGATGATGCAGTGGTATGGAGATTTGATCATTAATAATTGA

Upstream 100 bases:

>100_bases
CTATTAGTCTATTGAACTCAATAGTACTCCCTCAGGGTCAAGCTCAATGTGGGGGTATGAGTGGGGGTATAATTGTACCC
CCTGCTGAGAGGTACCCCCA

Downstream 100 bases:

>100_bases
CAGAACTAATTGCAACCTGCTTCAACTCACAATGAATGAAGCAGGTAAAAATATCTTCATTCAATAGTAAAACCAAGTTT
TCTTAATGTATCAGCTTCAC

Product: Integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKLTARQVETAKPKDKPYKLADGGGLYLLVNPNGKRYWRLKYRSLGKEKLLAIGVYPDVSLAEARSKREDAKRTLAVGND
PSLERKIEKLSRQQDAENSFEAITREWYQRRYDRWSVSYREEMLRTFEKDVFPYIGHRPIKDIKPMELLAVLSKIEARGA
TEKVRKVRQRCGEVWKYAVVTGRAEYNPAPDLASAVTPHEKEHYAFLTQDELPEFLRTLNTYAGSVLVKIAMQLLILTGV
RPGELRQAEWQEFDFERKVWNVPAERMKMRRPHLVPLSSQAIDLLNQLKPMTGAGALLFPGRNNPKKSMSDMALIVLVRR
IGYAGRVTGHGFRHTMSTILHEQGFNSAWIELQLAHVDKNSIRGTYNHAQYLEGRREMMQWYGDLIINN

Sequences:

>Translated_389_residues
MKLTARQVETAKPKDKPYKLADGGGLYLLVNPNGKRYWRLKYRSLGKEKLLAIGVYPDVSLAEARSKREDAKRTLAVGND
PSLERKIEKLSRQQDAENSFEAITREWYQRRYDRWSVSYREEMLRTFEKDVFPYIGHRPIKDIKPMELLAVLSKIEARGA
TEKVRKVRQRCGEVWKYAVVTGRAEYNPAPDLASAVTPHEKEHYAFLTQDELPEFLRTLNTYAGSVLVKIAMQLLILTGV
RPGELRQAEWQEFDFERKVWNVPAERMKMRRPHLVPLSSQAIDLLNQLKPMTGAGALLFPGRNNPKKSMSDMALIVLVRR
IGYAGRVTGHGFRHTMSTILHEQGFNSAWIELQLAHVDKNSIRGTYNHAQYLEGRREMMQWYGDLIINN
>Mature_389_residues
MKLTARQVETAKPKDKPYKLADGGGLYLLVNPNGKRYWRLKYRSLGKEKLLAIGVYPDVSLAEARSKREDAKRTLAVGND
PSLERKIEKLSRQQDAENSFEAITREWYQRRYDRWSVSYREEMLRTFEKDVFPYIGHRPIKDIKPMELLAVLSKIEARGA
TEKVRKVRQRCGEVWKYAVVTGRAEYNPAPDLASAVTPHEKEHYAFLTQDELPEFLRTLNTYAGSVLVKIAMQLLILTGV
RPGELRQAEWQEFDFERKVWNVPAERMKMRRPHLVPLSSQAIDLLNQLKPMTGAGALLFPGRNNPKKSMSDMALIVLVRR
IGYAGRVTGHGFRHTMSTILHEQGFNSAWIELQLAHVDKNSIRGTYNHAQYLEGRREMMQWYGDLIINN

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788690, Length=383, Percent_Identity=46.2140992167102, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI145693166, Length=387, Percent_Identity=43.6692506459948, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1788974, Length=386, Percent_Identity=37.3056994818653, Blast_Score=278, Evalue=6e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 44929; Mature: 44929

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTARQVETAKPKDKPYKLADGGGLYLLVNPNGKRYWRLKYRSLGKEKLLAIGVYPDVS
CCCCHHHHHCCCCCCCCEEEECCCCEEEEECCCCCEEEEEHHHHCCCHHEEEEECCCCCH
LAEARSKREDAKRTLAVGNDPSLERKIEKLSRQQDAENSFEAITREWYQRRYDRWSVSYR
HHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHH
EEMLRTFEKDVFPYIGHRPIKDIKPMELLAVLSKIEARGATEKVRKVRQRCGEVWKYAVV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHE
TGRAEYNPAPDLASAVTPHEKEHYAFLTQDELPEFLRTLNTYAGSVLVKIAMQLLILTGV
ECCCCCCCCCCHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPGELRQAEWQEFDFERKVWNVPAERMKMRRPHLVPLSSQAIDLLNQLKPMTGAGALLFP
CCCCCCHHHHHHHCHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEC
GRNNPKKSMSDMALIVLVRRIGYAGRVTGHGFRHTMSTILHEQGFNSAWIELQLAHVDKN
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCC
SIRGTYNHAQYLEGRREMMQWYGDLIINN
CCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLTARQVETAKPKDKPYKLADGGGLYLLVNPNGKRYWRLKYRSLGKEKLLAIGVYPDVS
CCCCHHHHHCCCCCCCCEEEECCCCEEEEECCCCCEEEEEHHHHCCCHHEEEEECCCCCH
LAEARSKREDAKRTLAVGNDPSLERKIEKLSRQQDAENSFEAITREWYQRRYDRWSVSYR
HHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHH
EEMLRTFEKDVFPYIGHRPIKDIKPMELLAVLSKIEARGATEKVRKVRQRCGEVWKYAVV
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHE
TGRAEYNPAPDLASAVTPHEKEHYAFLTQDELPEFLRTLNTYAGSVLVKIAMQLLILTGV
ECCCCCCCCCCHHHHCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPGELRQAEWQEFDFERKVWNVPAERMKMRRPHLVPLSSQAIDLLNQLKPMTGAGALLFP
CCCCCCHHHHHHHCHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCEEEEC
GRNNPKKSMSDMALIVLVRRIGYAGRVTGHGFRHTMSTILHEQGFNSAWIELQLAHVDKN
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCC
SIRGTYNHAQYLEGRREMMQWYGDLIINN
CCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]