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The map label for this gene is arsR [H]

Identifier: 218550115

GI number: 218550115

Start: 2867785

End: 2868138

Strand: Reverse

Name: arsR [H]

Synonym: EFER_2803

Alternate gene names: 218550115

Gene position: 2868138-2867785 (Counterclockwise)

Preceding gene: 218550118

Following gene: 218550113

Centisome position: 62.5

GC content: 53.95

Gene sequence:

>354_bases
ATGATGTCTCTAACTTCCCTACAACTCTTCAAAAACCTCTCCGATGAAACCCGTCTAGGGATCGTGCTGCTGCTCAGGGA
GATGGGAGAGCTGTGCGTGTGCGACCTCTGCACTGCGTTGGAACAGTCTCAGCCTAAGATCTCCCGCCATCTGGCAATGC
TCCGGGAAAGTGGTCTATTGCTGGATCGCAAACAGGGCAAGTGGGTTCACTACCGCTTATCTCCGCATATTCCTTCCTGG
GCTGCTCAGGTGATTGAGCAGGCATGGTTAAGCCAACAGGACGACGTACAGGCCATCGCCCGTAAGCTGGCATCGGCAAA
CTGCTCTGGTAGCGGTAAGGCTGTTTGCATCTAA

Upstream 100 bases:

>100_bases
GACACATCTCTTAAAAACGCATAAAACATATTCGTTTTTACGAATATGTAAATTGATTTTATTTTTTTAAGAGTACCCTG
ACTTCAAATGAACAGGAGGA

Downstream 100 bases:

>100_bases
AAAATTTGCCTTAACATATATGTTTTTTCGAATGTGATGTATTTGGAATGAAAACGTTAACGGTGTTTGACCCGGCAAAG
TGCTGCAGTACCGGCGTATG

Product: DNA-binding transcriptional repressor ArsR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 117; Mature: 117

Protein sequence:

>117_residues
MMSLTSLQLFKNLSDETRLGIVLLLREMGELCVCDLCTALEQSQPKISRHLAMLRESGLLLDRKQGKWVHYRLSPHIPSW
AAQVIEQAWLSQQDDVQAIARKLASANCSGSGKAVCI

Sequences:

>Translated_117_residues
MMSLTSLQLFKNLSDETRLGIVLLLREMGELCVCDLCTALEQSQPKISRHLAMLRESGLLLDRKQGKWVHYRLSPHIPSW
AAQVIEQAWLSQQDDVQAIARKLASANCSGSGKAVCI
>Mature_117_residues
MMSLTSLQLFKNLSDETRLGIVLLLREMGELCVCDLCTALEQSQPKISRHLAMLRESGLLLDRKQGKWVHYRLSPHIPSW
AAQVIEQAWLSQQDDVQAIARKLASANCSGSGKAVCI

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=116, Percent_Identity=75, Blast_Score=185, Evalue=9e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13049; Mature: 13049

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSLTSLQLFKNLSDETRLGIVLLLREMGELCVCDLCTALEQSQPKISRHLAMLRESGLL
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCE
LDRKQGKWVHYRLSPHIPSWAAQVIEQAWLSQQDDVQAIARKLASANCSGSGKAVCI
EECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEC
>Mature Secondary Structure
MMSLTSLQLFKNLSDETRLGIVLLLREMGELCVCDLCTALEQSQPKISRHLAMLRESGLL
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCE
LDRKQGKWVHYRLSPHIPSWAAQVIEQAWLSQQDDVQAIARKLASANCSGSGKAVCI
EECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]