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The map label for this gene is nadA [H]

Identifier: 218549684

GI number: 218549684

Start: 2415171

End: 2416214

Strand: Reverse

Name: nadA [H]

Synonym: EFER_2360

Alternate gene names: 218549684

Gene position: 2416214-2415171 (Counterclockwise)

Preceding gene: 218549685

Following gene: 218549683

Centisome position: 52.66

GC content: 50.0

Gene sequence:

>1044_bases
ATGAGCGTGATGTTTGATCCAGACACGGCGATTTATCCTTTCCCCACGAAACCGACGCCGTTAAGCATTGATGAAAAAGC
GTATTACCGCGAGAAGATAAAACGTCTGCTAAAAGAACGTAATGCGGTGATGGTTGCCCACTACTATACCGACCCCGAAA
TTCAACAACTGGCAGAAGAAACCGGTGGCTGTATTTCTGATTCTCTGGAAATGGCGCGCTTCGGTGCAAAGCATCCCGCT
TCTACGTTGTTAGTCGCTGGGGTGAGATTTATGGGAGAAACCGCCAAGATTCTCAGTCCGGAAAAAACAATTCTGATGCC
GACACTTCAGGCTGAATGTTCACTGGATCTCGGTTGCCCTGTTGATCAATTTAACGCATTTTGCGATGCCCATCCCGACC
GTACTGTCGTCGTCTACGCCAACACTTCTGCGGTGGTAAAAGCGCGCGCAGATTGGGTGGTAACTTCAAGCATTGCCGTC
GAACTTATTGATCATCTGGATAGTTTGGGGGAAAAAATCATCTGGGCACCCGACAAACATCTGGGGCGTTACGTGCAAAA
ACAGACGGGCGCAGACATTTTATGTTGGCAGGGTACCTGCATTGTGCATGATGAATTTAAGACTCAGGCGTTAACCCGCT
TGCAAAAACAATACCCGGATGCTGCCATACTGGTGCATCCAGAATCACCACAAGCTATTGTAGATATGGCAGATGCGGTC
GGTTCCACCAGTCAACTGATCGCTGCTGCGAAAACATTGCCACATCAGCGACTTATCGTGGCAACCGATCGGGGTATTTT
CTACAAAATGCAGCAGGCGGTGCCAGATAAAGAGTTACTGGAAGCACCAACCGCGGGTGAGGGCGCAACCTGCCGCAGCT
GCGCGCATTGTCCTTGGATGGCGATGAATGGCCTTCAGGCCATCGCAGAAGCATTAGAACAGGAAGAAAGCAATTACGAG
GTTCATGTTGATGAAAGGCTGCGAGAGAGGGCGCTGGTGCCGCTTAATCGTATGCTGGATTTTGCGGCTACACTACGTGG
ATAA

Upstream 100 bases:

>100_bases
TCGACTATCTTGTTTAGCATATAAAACAAATTATGCCGATAACAGCGAATATCACGCTTATGTCGGTTTTAACGTTAAGC
CTGTAAAACGAGATGGTAAG

Downstream 100 bases:

>100_bases
CTGATAATAAGGCGTCAGGTTACGCTTTGGGGGAAAGATGGATTTTTTTAGTGTGCAGAATATCCTGGTACATATACCAA
TAGGTGCTGGCGGTTATGAT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSVMFDPDTAIYPFPTKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPA
STLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVDQFNAFCDAHPDRTVVVYANTSAVVKARADWVVTSSIAV
ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGADILCWQGTCIVHDEFKTQALTRLQKQYPDAAILVHPESPQAIVDMADAV
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEESNYE
VHVDERLRERALVPLNRMLDFAATLRG

Sequences:

>Translated_347_residues
MSVMFDPDTAIYPFPTKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPA
STLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVDQFNAFCDAHPDRTVVVYANTSAVVKARADWVVTSSIAV
ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGADILCWQGTCIVHDEFKTQALTRLQKQYPDAAILVHPESPQAIVDMADAV
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEESNYE
VHVDERLRERALVPLNRMLDFAATLRG
>Mature_346_residues
SVMFDPDTAIYPFPTKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPAS
TLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVDQFNAFCDAHPDRTVVVYANTSAVVKARADWVVTSSIAVE
LIDHLDSLGEKIIWAPDKHLGRYVQKQTGADILCWQGTCIVHDEFKTQALTRLQKQYPDAAILVHPESPQAIVDMADAVG
STSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEESNYEV
HVDERLRERALVPLNRMLDFAATLRG

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=347, Percent_Identity=97.1181556195965, Blast_Score=704, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38398; Mature: 38267

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMFDPDTAIYPFPTKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEE
CCEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHH
TGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCP
HCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCC
VDQFNAFCDAHPDRTVVVYANTSAVVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKH
HHHHHHHHCCCCCCEEEEEECCCEEEEECCCEEEHHHHHHHHHHHHHHHCCCEEECCCHH
LGRYVQKQTGADILCWQGTCIVHDEFKTQALTRLQKQYPDAAILVHPESPQAIVDMADAV
HHHHHHHHCCCCEEEECCEEEEECHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLQAIAEALEQEESNYEVHVDERLRERALVPLNRMLDFAATLRG
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SVMFDPDTAIYPFPTKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEE
CEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHH
TGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCP
HCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCCCCCCC
VDQFNAFCDAHPDRTVVVYANTSAVVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKH
HHHHHHHHCCCCCCEEEEEECCCEEEEECCCEEEHHHHHHHHHHHHHHHCCCEEECCCHH
LGRYVQKQTGADILCWQGTCIVHDEFKTQALTRLQKQYPDAAILVHPESPQAIVDMADAV
HHHHHHHHCCCCEEEECCEEEEECHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHH
GSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLQAIAEALEQEESNYEVHVDERLRERALVPLNRMLDFAATLRG
HHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA