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The map label for this gene is modF [H]

Identifier: 218549673

GI number: 218549673

Start: 2404533

End: 2406005

Strand: Direct

Name: modF [H]

Synonym: EFER_2349

Alternate gene names: 218549673

Gene position: 2404533-2406005 (Clockwise)

Preceding gene: 218549672

Following gene: 218549674

Centisome position: 52.4

GC content: 51.93

Gene sequence:

>1473_bases
ATGTCATCGTTGCAAATTTTGCAAGGCACGTTTCGTCTTGGCGACACAAAAACGCTGCAATTGCCTCAGCTAACGTTAAA
CGCGGGTGATAGTTGGGCGTTTGTCGGTTCTAATGGCAGCGGGAAATCGGCGCTGGCCCGCGCGCTGGCGGGGGAACTTC
CGCTTTTGAAAGGTGAACGGCAAAGTCAGTTTTCCCATATTACTCGTCTCTCCTTCGAGCAATTGCAAAAGCTCGTCAGC
GACGAATGGCTGCGGAATAACACCGATATGCTCGCCCCTGGCGAAGATGACACCGGACGGACTACGGCTGAAATCATTCA
GGATGAAGTAAAGGATGCACCGCGTTGCATACAACTGGCGCAGCAGTTCGGTATTACCGCCCTCCTCGACCGACGCTTTA
AATACCTTTCCACTGGCGAGACGCGAAAAACCCTGCTGTGTCAGGCGCTGATGTCGGAGCCAGACTTGTTGATTCTTGAT
GAGCCGTTCGATGGCCTGGATGTTGCCTCACGTCAGCAGCTGGCTGAGCGACTCGCCTCGTTACATCAGTCCGGTATTAC
TCTGGTACTGGTGCTCAATCGCTTCGATGAGATCCCGGAATTTGTCCAGTTTGCTGGCGTGCTGGCGGATTGCACGTTAG
CGGAAACTGGCGCTAAAGAGGAACTGCTCCAACAAGCACTCGTCGCGCAACTGGCACATAGCGAACAGCTTGAAGGTGTG
CAACTGCCGGAGCCAGATGAACCTTCAGCACGTCACGCCTTACCCGCCAACGAACCGCGCATTGTGCTGAAAAATGGCGT
GGTTTCTTATAACGATCGCCCCATTCTTAATAACCTTAGCTGGCAGGTGAATCCAGGCGAACACTGGCAAATTGTCGGGC
CAAATGGCGCGGGAAAATCGACGCTATTAAGCCTGATTACTGGCGATCATCCGCAAGGTTACAGCAACGATTTAACGCTT
TTTGGACGACGTCGCGGCAGCGGCGAAACCATCTGGGATATCAAAAAGCATATCGGTTACGTCAGCAGTAGTTTGCATCT
GGATTACCGGGTCAGCACTACCGTGCGTAATGTGATCCTTTCTGGCTATTTTGATTCGATTGGCATTTATCAGGCTGTTT
CAGATCGCCAGCAAAAACTGGTGCAGCAGTGGCTGGATATTCTCGGCATTGATAAACGCACGGCTGACGCGCCTTACCAT
AGTCTTTCCTGGGGACAGCAACGTCTGGCGCTGATCGTTCGCGCACTGGTGAAGCATCCGACTTTGCTTATTCTTGATGA
ACCTTTACAGGGACTTGATCCACTCAATCGCCAGCTTATCCGCCGTTTTGTTGATGTGCTGATTAGCGAAGGTGAAACGC
AATTATTGTTTGTTTCACACCACGCCGAAGATGCGCCCGCCTGTATTTCCCATCGTCTTGAGTTCGTGCCGGACGGTGAC
CTCTATCGTTATGCGCTGACAAAAATAAACTGA

Upstream 100 bases:

>100_bases
GCCGACCGGGTGATTATCGCGACCTTGTGCTAAGCACATTGACAATCTTTGCTGGAACACGTATCCCTGTCAGTAATCGC
TGCAAAAAATGGGATATAAA

Downstream 100 bases:

>100_bases
GTCGGTAATGCTGACTGTACCGGAGGCGGCCTTAGCGCCCTCTCCGGCCTAAAGTTCGACACATCCAGGAATGAAACCGC
GACTTTTTTCAGATAAAAAG

Product: molybdenum transport ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQKLVS
DEWLRNNTDMLAPGEDDTGRTTAEIIQDEVKDAPRCIQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
EPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
QLPEPDEPSARHALPANEPRIVLKNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPYH
SLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACISHRLEFVPDGD
LYRYALTKIN

Sequences:

>Translated_490_residues
MSSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQKLVS
DEWLRNNTDMLAPGEDDTGRTTAEIIQDEVKDAPRCIQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
EPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
QLPEPDEPSARHALPANEPRIVLKNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTL
FGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPYH
SLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACISHRLEFVPDGD
LYRYALTKIN
>Mature_489_residues
SSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQKLVSD
EWLRNNTDMLAPGEDDTGRTTAEIIQDEVKDAPRCIQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDE
PFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGVQ
LPEPDEPSARHALPANEPRIVLKNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLF
GRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPYHS
LSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACISHRLEFVPDGDL
YRYALTKIN

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=167, Percent_Identity=28.1437125748503, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI27262626, Length=167, Percent_Identity=28.1437125748503, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1786975, Length=489, Percent_Identity=97.9550102249489, Blast_Score=978, Evalue=0.0,
Organism=Escherichia coli, GI48994943, Length=379, Percent_Identity=27.4406332453826, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788897, Length=499, Percent_Identity=23.8476953907816, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789991, Length=466, Percent_Identity=23.6051502145923, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1787041, Length=540, Percent_Identity=22.7777777777778, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI48995001, Length=463, Percent_Identity=23.7580993520518, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788506, Length=474, Percent_Identity=26.5822784810127, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787792, Length=480, Percent_Identity=23.75, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790525, Length=482, Percent_Identity=22.1991701244813, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1790190, Length=480, Percent_Identity=24.1666666666667, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI2367384, Length=485, Percent_Identity=25.1546391752577, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787029, Length=222, Percent_Identity=29.7297297297297, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789593, Length=228, Percent_Identity=28.5087719298246, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI145693107, Length=517, Percent_Identity=23.5976789168279, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788225, Length=180, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786319, Length=193, Percent_Identity=31.0880829015544, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081782, Length=203, Percent_Identity=27.5862068965517, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786563, Length=200, Percent_Identity=30.5, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790544, Length=228, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789864, Length=217, Percent_Identity=26.7281105990783, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788472, Length=467, Percent_Identity=22.2698072805139, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787112, Length=230, Percent_Identity=27.8260869565217, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082268, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788761, Length=219, Percent_Identity=26.9406392694064, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790162, Length=238, Percent_Identity=23.5294117647059, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=281, Percent_Identity=27.4021352313167, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115533608, Length=226, Percent_Identity=27.8761061946903, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320266, Length=394, Percent_Identity=29.1878172588832, Blast_Score=160, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24650853, Length=237, Percent_Identity=32.0675105485232, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24650855, Length=237, Percent_Identity=32.0675105485232, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281362751, Length=226, Percent_Identity=32.3008849557522, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28574744, Length=196, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221512771, Length=202, Percent_Identity=26.7326732673267, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920532, Length=183, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24580930, Length=183, Percent_Identity=29.5081967213115, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI85725262, Length=214, Percent_Identity=29.9065420560748, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 54499; Mature: 54367

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGER
CCCHHHHHHHHCCCCCCEEECCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCH
QSQFSHITRLSFEQLQKLVSDEWLRNNTDMLAPGEDDTGRTTAEIIQDEVKDAPRCIQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHH
QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAERLAS
HHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
HHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
QLPEPDEPSARHALPANEPRIVLKNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCCEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPYHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACISHRLEFVPDGD
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCC
LYRYALTKIN
EEEHEEEECC
>Mature Secondary Structure 
SSLQILQGTFRLGDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGER
CCHHHHHHHHCCCCCCEEECCEEEECCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCH
QSQFSHITRLSFEQLQKLVSDEWLRNNTDMLAPGEDDTGRTTAEIIQDEVKDAPRCIQLA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHHH
QQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAERLAS
HHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHH
LHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQLEGV
HHHCCCEEEEEEHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
QLPEPDEPSARHALPANEPRIVLKNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKS
CCCCCCCCCCCCCCCCCCCEEEEECCEEECCCCCCCCCCCEEECCCCCEEEECCCCCCHH
TLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVIL
HHHHHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCEEEEEEHHHHHHHHHH
SGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTADAPYHSLSWGQQRLALIVRALVKHP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACISHRLEFVPDGD
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHCCCCCCCCC
LYRYALTKIN
EEEHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]