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The map label for this gene is ybhA [H]

Identifier: 218549667

GI number: 218549667

Start: 2399909

End: 2400727

Strand: Direct

Name: ybhA [H]

Synonym: EFER_2343

Alternate gene names: 218549667

Gene position: 2399909-2400727 (Clockwise)

Preceding gene: 218549665

Following gene: 218549672

Centisome position: 52.3

GC content: 47.37

Gene sequence:

>819_bases
ATGTCCGCTCGCGTGATTGCCCTTGATTTAGACGGAACGTTACTGACGCCGAAAAAGACATTACTCCCTTCTTCCCTTGA
AGCGTTATCACGCGCCAGAGAAGCGGGATATCAACTTATCATTGTCACTGGTCGCCATCACGTCGCTATTCATCCTTTTT
ATCAGGCACTGGCATTAGATACACCTGCAATTTGCTGTAACGGAACCTATTTGTATGATTATCAAGCAAAAAAGGTGTTA
CAAGCCGATCCAATGCCTGTTGACCAGGCATTACAATTAATTGATTTGCTCAATCAGCATAATATTCCTGGCCTGATGTA
CGTCGATGATGCGATGGTGTATGAGCATCCTACCGGGCATGTTATTCGCACTTCTAACTGGGCTCAGACTCTGCCTGAAC
ATCAGCGTCCTACTTTTACACAAGTGCCTTCACTGGCGCAGGCGGCACGTGATGTCAATGCCGTATGGAAGTTTGCATTA
ACCGATGAAGACCTGCCGAAATTACGCCAGTTCGCTAAGCAGGTGGAACAGCAGCTGGGCCTCGAATGCGAATGGTCATG
GCATGACCAGGTGGATGTAGCACGCAAAGGTAATAGCAAAGGCAAACGCCTTACTCAATGGATCGAAGCGCAGGGCTGGT
CGATGGAAAATGTTATTGCGTTTGGCGATAACTATAACGATATCAGCATGCTGGAAGCCGCAGGTACTGGTGTTGCTATG
GGCAATGCAGATGATGCAGTGAAAGAACGTGCCAATATTGTGATTGGTGATAACACTACCGACAGCATTGCCCAGTTTAT
TTACAGCCGCCTGATTTGA

Upstream 100 bases:

>100_bases
CGTTCAATGCTGAATATACGCACAAAATTTTGTCTACTATCTGACTCGGTGTACCATTCGCGCAGACAAAACTCTTAACC
TTAATCTGGAAAAATACCCC

Downstream 100 bases:

>100_bases
TCAGGCGGTTATCGACACACTCTTAATTTGTGCATACAACCACAGGCCAGGTTTGATCGCCAGTTCATCCCTGGCCCAGG
GGCTAATTCGTGCCCACAAC

Product: phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSARVIALDLDGTLLTPKKTLLPSSLEALSRAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYQAKKVL
QADPMPVDQALQLIDLLNQHNIPGLMYVDDAMVYEHPTGHVIRTSNWAQTLPEHQRPTFTQVPSLAQAARDVNAVWKFAL
TDEDLPKLRQFAKQVEQQLGLECEWSWHDQVDVARKGNSKGKRLTQWIEAQGWSMENVIAFGDNYNDISMLEAAGTGVAM
GNADDAVKERANIVIGDNTTDSIAQFIYSRLI

Sequences:

>Translated_272_residues
MSARVIALDLDGTLLTPKKTLLPSSLEALSRAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYQAKKVL
QADPMPVDQALQLIDLLNQHNIPGLMYVDDAMVYEHPTGHVIRTSNWAQTLPEHQRPTFTQVPSLAQAARDVNAVWKFAL
TDEDLPKLRQFAKQVEQQLGLECEWSWHDQVDVARKGNSKGKRLTQWIEAQGWSMENVIAFGDNYNDISMLEAAGTGVAM
GNADDAVKERANIVIGDNTTDSIAQFIYSRLI
>Mature_271_residues
SARVIALDLDGTLLTPKKTLLPSSLEALSRAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYQAKKVLQ
ADPMPVDQALQLIDLLNQHNIPGLMYVDDAMVYEHPTGHVIRTSNWAQTLPEHQRPTFTQVPSLAQAARDVNAVWKFALT
DEDLPKLRQFAKQVEQQLGLECEWSWHDQVDVARKGNSKGKRLTQWIEAQGWSMENVIAFGDNYNDISMLEAAGTGVAMG
NADDAVKERANIVIGDNTTDSIAQFIYSRLI

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates pyridoxalphosphate and erythrose 4-phosphate [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI1786982, Length=272, Percent_Identity=86.0294117647059, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI48994981, Length=284, Percent_Identity=28.169014084507, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081741, Length=286, Percent_Identity=28.3216783216783, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR000150
- InterPro:   IPR006380 [H]

Pfam domain/function: PF00702 Hydrolase; PF05116 S6PP [H]

EC number: NA

Molecular weight: Translated: 30331; Mature: 30200

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS01228 COF_1 ; PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARVIALDLDGTLLTPKKTLLPSSLEALSRAREAGYQLIIVTGRHHVAIHPFYQALALD
CCCEEEEEECCCEEECCHHHHCHHHHHHHHHHHHCCCEEEEEECCCEEEECHHHHHHHCC
TPAICCNGTYLYDYQAKKVLQADPMPVDQALQLIDLLNQHNIPGLMYVDDAMVYEHPTGH
CCCEEECCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCC
VIRTSNWAQTLPEHQRPTFTQVPSLAQAARDVNAVWKFALTDEDLPKLRQFAKQVEQQLG
EEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHC
LECEWSWHDQVDVARKGNSKGKRLTQWIEAQGWSMENVIAFGDNYNDISMLEAAGTGVAM
CEEEECCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCCCCEEE
GNADDAVKERANIVIGDNTTDSIAQFIYSRLI
CCCHHHHHHCCCEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SARVIALDLDGTLLTPKKTLLPSSLEALSRAREAGYQLIIVTGRHHVAIHPFYQALALD
CCEEEEEECCCEEECCHHHHCHHHHHHHHHHHHCCCEEEEEECCCEEEECHHHHHHHCC
TPAICCNGTYLYDYQAKKVLQADPMPVDQALQLIDLLNQHNIPGLMYVDDAMVYEHPTGH
CCCEEECCCEEEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCEEEEECCCCC
VIRTSNWAQTLPEHQRPTFTQVPSLAQAARDVNAVWKFALTDEDLPKLRQFAKQVEQQLG
EEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHC
LECEWSWHDQVDVARKGNSKGKRLTQWIEAQGWSMENVIAFGDNYNDISMLEAAGTGVAM
CEEEECCCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHCCCCEEE
GNADDAVKERANIVIGDNTTDSIAQFIYSRLI
CCCHHHHHHCCCEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665460; 8564363; 8905232; 9278503 [H]