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The map label for this gene is ybiN [H]

Identifier: 218549626

GI number: 218549626

Start: 2359038

End: 2359964

Strand: Reverse

Name: ybiN [H]

Synonym: EFER_2301

Alternate gene names: 218549626

Gene position: 2359964-2359038 (Counterclockwise)

Preceding gene: 218549632

Following gene: 218549623

Centisome position: 51.43

GC content: 53.94

Gene sequence:

>927_bases
ATGTCCGCCCAGAAACCGGGGTTGCATCCGCGCAACCGTCATCACAGCCGCTACGATCTTGCCACGCTTTGTCAGGTGAA
TCCTGAACTGAAGCAATTCCTCACGCTAACGCCTGCCGGGGAACAAAGCGTAGACTTCGCCAATCCACTGGCGGTGAAGG
CGCTCAATAAGGCGTTACTGGCCCATTTTTACGCTGTGGCGAACTGGGATATTCCAGACGGTTTTCTCTGCCCACCAGTA
CCGGGCCGGGCGGATTATATTCATCATCTTGCTGATTTACTGGCTGAAGCAAGCGGAACGATCCCTGCCAGGGCCAGCAT
TCTGGATATTGGCGTTGGTGCGAACTGTATTTATCCGCTGATTGGCGTACACGAATATGGCTGGCGTTTTACCGGTAGTG
AAACCAGCAGCCAGGCGTTAAGCAGTGCGCAGGCGATCATCAGTGCTAATCCGGGGCTTAACCGCGCCATTCGTCTGCGT
CGGCAAAAAGAGAGTGGGGCGATTTTTAACGGCATCATCCATAAAAACGAGCAATACGACGCGACCTTGTGTAACCCGCC
ATTCCACGATTCCGCTGCTGCGGCACGGGCAGGTAGTGAGCGTAAACGCCGTAACCTGGGGCTGAACAAAGACGATGCAC
TGAACTTTGGCGGCCAGCAACAGGAGTTGTGGTGTGAAGGCGGTGAAGTCACCTTTATCAAAAAGATGATTGAAGAGAGC
AAAGGCTTCGCGAAGCAGGTGATGTGGTTTACCTCACTGGTATCTCGTGGTGAAAACTTACCGCCGTTGTATCGTGCCCT
GACGGACGTGGGCGCGGTGAAGGTGGTTAAAAAAGAGATGGCCCAGGGGCAAAAGCAGAGTCGCTTTATTGCCTGGACCT
TTATGAACGACGAGCAGCGCCGCCGTTTTGTCAATCGCCAGCGTTAA

Upstream 100 bases:

>100_bases
ACCATAGTCATGTCAAGGTTTGGAGAATGATAAACGCAGCCAGATATTTACCCTGTCGCGTTATGCGGGTATCTTACGCC
GCTGCTTAAAGGAGAATGCT

Downstream 100 bases:

>100_bases
AGCGTTGGTTCCCCCGGCGGCAACGGTTCAGCCGGGGTCGCGCCCGGAGCAGGCAGCACCTGATAAGTCTGCACTGGCGC
GCGAACACCCGCCAGGTCGA

Product: SAM-dependent methyltransferase

Products: NA

Alternate protein names: 23S rRNA mA1618 methyltransferase; rRNA adenine N-6-methyltransferase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSAQKPGLHPRNRHHSRYDLATLCQVNPELKQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPV
PGRADYIHHLADLLAEASGTIPARASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLR
RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVTFIKKMIEES
KGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR

Sequences:

>Translated_308_residues
MSAQKPGLHPRNRHHSRYDLATLCQVNPELKQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPV
PGRADYIHHLADLLAEASGTIPARASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLR
RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVTFIKKMIEES
KGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR
>Mature_307_residues
SAQKPGLHPRNRHHSRYDLATLCQVNPELKQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVP
GRADYIHHLADLLAEASGTIPARASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRR
QKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVTFIKKMIEESK
GFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR

Specific function: Specifically methylates the adenine in position 1618 of 23S rRNA [H]

COG id: COG3129

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. METT10D/rlmF family [H]

Homologues:

Organism=Homo sapiens, GI122114654, Length=293, Percent_Identity=31.0580204778157, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI87081786, Length=308, Percent_Identity=99.025974025974, Blast_Score=639, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32564931, Length=308, Percent_Identity=25.6493506493506, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32564933, Length=308, Percent_Identity=24.3506493506494, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363415, Length=291, Percent_Identity=29.553264604811, Blast_Score=121, Evalue=7e-28,
Organism=Drosophila melanogaster, GI19922302, Length=291, Percent_Identity=29.553264604811, Blast_Score=121, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016909
- InterPro:   IPR010286 [H]

Pfam domain/function: PF05971 Methyltransf_10 [H]

EC number: =2.1.1.181 [H]

Molecular weight: Translated: 34224; Mature: 34093

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQKPGLHPRNRHHSRYDLATLCQVNPELKQFLTLTPAGEQSVDFANPLAVKALNKALL
CCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHH
AHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIPARASILDIGVGANCIYPL
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHH
IGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYD
HHHHHCCCEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEHHHHCCCCCCC
ATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVTFIKKMIEES
CEECCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCHHEEECCCCHHHHHHHHHHH
KGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEEEECHHHH
RRFVNRQR
HHHHCCCC
>Mature Secondary Structure 
SAQKPGLHPRNRHHSRYDLATLCQVNPELKQFLTLTPAGEQSVDFANPLAVKALNKALL
CCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHH
AHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIPARASILDIGVGANCIYPL
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHHHH
IGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYD
HHHHHCCCEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEHHHHCCCCCCC
ATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGGQQQELWCEGGEVTFIKKMIEES
CEECCCCCCCCHHHHHCCHHHHHHHCCCCCCCCCCCCCCCHHEEECCCCHHHHHHHHHHH
KGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEEEECHHHH
RRFVNRQR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA