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The map label for this gene is yeiC [H]

Identifier: 218549580

GI number: 218549580

Start: 2310888

End: 2311934

Strand: Reverse

Name: yeiC [H]

Synonym: EFER_2252

Alternate gene names: 218549580

Gene position: 2311934-2310888 (Counterclockwise)

Preceding gene: 218549581

Following gene: 218549579

Centisome position: 50.38

GC content: 44.7

Gene sequence:

>1047_bases
ATGAACACGTGTTTAAATCTGAACATGTGCTCTAATAGTCTTATCTTTCATAAAGACTATTTTACCCAATTTCTTCGTTG
GCAATTTATTGCCAGGGGGCGTGCTATGCGCGAAAAGGACTACATAGTAATTATTGGTTCGGCGAATATTGATGTGGCGG
GGTATTCACACCAGTCATTGAATTATGCGGATTCGAATCCCGGAAAAATAAAATTTACCCCAGGCGGTGTGGGGAGAAAT
ATCGCTCATAATCTGGCGTTGCTGGGAAAAAATGCCTGGCTTTTAAGTGCAGTGGGCGGTGATTTCTATGGACAGTCATT
ACTGGCGCAAACTAATCAATCTGGTGTTTATGTCGATAAATGCTTAATTGTGCCGGGTGAAAATACCTCCAGTTATTTAT
CACTGCTCGATAATACCGGAGAAATGCTTGTTGCTATTAATGACATGAATATTAGCGACTGTATTTCTGCAAAATTTCTG
TCTCAGCATCAGGAATTTATTCGTGGTGCAAATGTTATTGTCGCGGATTGCAACCTGAGTGAAGAGGCGCTGGTCTGGGT
TCTGGAAAATAGCGGGGAAACGCCTGTATTTATTGATCCGGTATCGGCGTGGAAATGCGTCAAAATTCGCGATCATCTGA
GCAAAATTCATACTCTGAAACCTAACCGTCTTGAAGCTGAAACACTGAGTGGAATTGCACTGTCTGGGCGTGAAGATGTC
GCAAAGGTCGCAGCCTGGTTTCATCAACACGGCCTGAACCGCCTGGTGCTGAGCATGGGCGGTGATGGTGTTTATTACAG
TGATATCGGCGGTGAAAGTGGCTGGTCTGCGCCGATTAAAACCAATGTCATTAATGTTACCGGAGCAGGTGACGCCATGA
TGGCGGGGCTGGCCTCCTGTTGGGTAGATGGGATGTCGTTTACCGATTCTGTTCGATTTGCGCAGGGATGTTCGTCAATG
GCACTTGCCTGTGAATATACCAATAACCCTGAATTATCAATTGCCAATGTTACATCGTTAGTGGAGAACTCCGAATGTCT
GAATTAA

Upstream 100 bases:

>100_bases
CCTTTTATTGCTGTATAAGCAACCAAATTTTGTGACCGCCTTCATATCTGGCTTATTTCGCTTTTTCTGATCGATTTACA
TTAATTTAAACAGGTCTATT

Downstream 100 bases:

>100_bases
CTCTGTCCCCTGAACTATTACAAATATCTGCCGAAGTACAAGAAGCTTTAAAAAATAAAAAACCGATTGTTGCTCTTGAA
TCAACCATTATTTCGCATGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MNTCLNLNMCSNSLIFHKDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSHQSLNYADSNPGKIKFTPGGVGRN
IAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDKCLIVPGENTSSYLSLLDNTGEMLVAINDMNISDCISAKFL
SQHQEFIRGANVIVADCNLSEEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGREDV
AKVAAWFHQHGLNRLVLSMGGDGVYYSDIGGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMSFTDSVRFAQGCSSM
ALACEYTNNPELSIANVTSLVENSECLN

Sequences:

>Translated_348_residues
MNTCLNLNMCSNSLIFHKDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSHQSLNYADSNPGKIKFTPGGVGRN
IAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDKCLIVPGENTSSYLSLLDNTGEMLVAINDMNISDCISAKFL
SQHQEFIRGANVIVADCNLSEEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGREDV
AKVAAWFHQHGLNRLVLSMGGDGVYYSDIGGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMSFTDSVRFAQGCSSM
ALACEYTNNPELSIANVTSLVENSECLN
>Mature_348_residues
MNTCLNLNMCSNSLIFHKDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSHQSLNYADSNPGKIKFTPGGVGRN
IAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDKCLIVPGENTSSYLSLLDNTGEMLVAINDMNISDCISAKFL
SQHQEFIRGANVIVADCNLSEEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGREDV
AKVAAWFHQHGLNRLVLSMGGDGVYYSDIGGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMSFTDSVRFAQGCSSM
ALACEYTNNPELSIANVTSLVENSECLN

Specific function: Catalyzes the phosphorylation of pseudouridine to pseudouridine 5'-phosphate (PsiMP) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788491, Length=313, Percent_Identity=87.8594249201278, Blast_Score=578, Evalue=1e-166,
Organism=Escherichia coli, GI1788484, Length=311, Percent_Identity=40.8360128617363, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1790193, Length=277, Percent_Identity=23.1046931407942, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17532905, Length=320, Percent_Identity=24.0625, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24580669, Length=281, Percent_Identity=28.8256227758007, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.83 [H]

Molecular weight: Translated: 37769; Mature: 37769

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTCLNLNMCSNSLIFHKDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSHQSL
CCCEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCCCCC
NYADSNPGKIKFTPGGVGRNIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDK
CCCCCCCCEEEECCCCCCCHHHHHHHEECCCCEEEEECCCCHHCCHHHHHCCCCCEEEEE
CLIVPGENTSSYLSLLDNTGEMLVAINDMNISDCISAKFLSQHQEFIRGANVIVADCNLS
EEEEECCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
EEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGREDV
CCEEEEEEECCCCCCEEECCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHCCEEECCHHHH
AKVAAWFHQHGLNRLVLSMGGDGVYYSDIGGESGWSAPIKTNVINVTGAGDAMMAGLASC
HHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
WVDGMSFTDSVRFAQGCSSMALACEYTNNPELSIANVTSLVENSECLN
HHCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHCCCCCCC
>Mature Secondary Structure
MNTCLNLNMCSNSLIFHKDYFTQFLRWQFIARGRAMREKDYIVIIGSANIDVAGYSHQSL
CCCEEEEEECCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEECCCCCCC
NYADSNPGKIKFTPGGVGRNIAHNLALLGKNAWLLSAVGGDFYGQSLLAQTNQSGVYVDK
CCCCCCCCEEEECCCCCCCHHHHHHHEECCCCEEEEECCCCHHCCHHHHHCCCCCEEEEE
CLIVPGENTSSYLSLLDNTGEMLVAINDMNISDCISAKFLSQHQEFIRGANVIVADCNLS
EEEEECCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
EEALVWVLENSGETPVFIDPVSAWKCVKIRDHLSKIHTLKPNRLEAETLSGIALSGREDV
CCEEEEEEECCCCCCEEECCCCCEEEEHHHHHHHHHHCCCCCCCCHHHHCCEEECCHHHH
AKVAAWFHQHGLNRLVLSMGGDGVYYSDIGGESGWSAPIKTNVINVTGAGDAMMAGLASC
HHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHH
WVDGMSFTDSVRFAQGCSSMALACEYTNNPELSIANVTSLVENSECLN
HHCCCCCCHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 3076173 [H]