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The map label for this gene is baeS [H]

Identifier: 218549495

GI number: 218549495

Start: 2206156

End: 2207559

Strand: Direct

Name: baeS [H]

Synonym: EFER_2165

Alternate gene names: 218549495

Gene position: 2206156-2207559 (Clockwise)

Preceding gene: 218549494

Following gene: 218549496

Centisome position: 48.08

GC content: 53.85

Gene sequence:

>1404_bases
ATGAAGTTCTGGCGACCCGGTATTACCGGCAAACTGTTTCTGGCGATTTTCGCCACCTGCATTGTCTTATTGATCACGAT
GCACTGGGCGGTACGTATCAGTTTTGAGCGCGGCTTTATCGATTACATCAAGCATGGTAATGAACAACGGCTGCAAATGC
TCGGCGATGCGCTTGGTGAGCAGTACGCCCAGCACGGGAACTGGCGCTTCCTGCGTAATAACGATCGCTTTGTATTTCAG
ATCCTACGTTCGCTGGAGCATGATAACAACGAAGATAAGCCCGGCCCCGGTATGCCGCCACACGGTTGGCGCACGCAATT
CTGGGTGGTTGATCAAAACAACAAAGTGCTGGTTGGCCCGCGAGCACCGATTCCACCAGACGGCACACGGCGGCCCATTA
TGGTCAATGGGGCAGAAGTGGGTGCGGTGATCGCCTCCCCTGTTGAACGACTGACCCGCAATACCGATATCAATTTTGAC
AGACAACAGAGGCAAACCAGTTGGCTGATTGTCGCTTTATCTACCTTATTAGCAGCGCTGGCGACATTCCCACTGGCGCG
CGGTTTGCTGGCTCCGGTCAAACGACTGGTGGACGGTACACACAAACTGGCAGCGGGCGATTTCACTACTCGCGTGACGC
CCACCAGCGAAGATGAACTAGGGAAACTGGCGCAAGACTTCAACCAGCTCGCCAGCACCCTGGAGAAAAACCAACAGATG
CGCCGCGATTTTATGGCCGATATCTCCCACGAGCTGCGCACGCCTTTAGCGGTACTGCGCGGCGAACTGGAAGCTATTCA
GGATGGCGTGCGTAAATTCACGCCGGAGACGGTGGCTTCTTTACAGGCAGAGGTCGGTACACTGACCAAACTGGTGGATG
ATCTTCATCAATTGTCGATGTCTGATGAAGGCGCTCTCGCCTACCAGAAATCGTCGGTGGATCTGATCCCGCTACTGGAA
GTCGCGGGTGGCGCATTTCGTGAGCGTTTCGCCAGCCGCGGGCTGAAACTGCAATTTTCCCTGCCAGACAGCATTACCGT
ATTTGGCGATCGCGATCGTTTAATGCAGTTGTTCAATAACTTACTGGAAAACAGCCTGCGCTATACCGACAGCGGCGGCA
GCTTGCATATCTCTGCCGAGCAACATGACAAAACGGTGCGCCTGACCTTTGCCGACAGTGCACCGGGCGTTAGTGACGAT
CAACTGCAAAAATTGTTTGAGCGTTTTTATCGCACCGAAGGTTCCCGCAACCGTGCCAGCGGCGGTTCCGGCTTGGGGCT
GGCTATTTGTCTTAACATTGTTGAAGCACATAATGGTCGCATTGTTGCCGCTCATTCGCCTTTTGGCGGGGTAAGCATTA
CAGTAGAGTTACCGCTGGAACGGGATTTACAGAGAGAAGTATGA

Upstream 100 bases:

>100_bases
GCATGGCGCTTATCATCGCCCTTCCGGCGTTCATCTTTGCCAGAGTTCCGAACGATACGCATCAAAATGTCGCTATTTCG
CGGCGAAAAAGGAGCGCGCA

Downstream 100 bases:

>100_bases
CCGAGTTACCAATCGACGAAAACACGCCACGTATTTTGATCGTGGAAGATGAACCGAAGCTGGGGCAGTTGCTTATTGAT
TATCTGCGTGCTGCGAGCTA

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKSSVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLHISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIVAAHSPFGGVSITVELPLERDLQREV

Sequences:

>Translated_467_residues
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKSSVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLHISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIVAAHSPFGGVSITVELPLERDLQREV
>Mature_467_residues
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFD
RQQRQTSWLIVALSTLLAALATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKSSVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLHISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIVAAHSPFGGVSITVELPLERDLQREV

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=467, Percent_Identity=96.7880085653105, Blast_Score=900, Evalue=0.0,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=29.6551724137931, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1790346, Length=272, Percent_Identity=28.3088235294118, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786912, Length=276, Percent_Identity=29.7101449275362, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786600, Length=253, Percent_Identity=27.6679841897233, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787374, Length=299, Percent_Identity=26.4214046822742, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788713, Length=243, Percent_Identity=28.3950617283951, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=27.6859504132231, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788279, Length=285, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=30, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790551, Length=299, Percent_Identity=28.0936454849498, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87081816, Length=254, Percent_Identity=28.3464566929134, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=303, Percent_Identity=24.0924092409241, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082128, Length=292, Percent_Identity=23.972602739726, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790436, Length=225, Percent_Identity=27.5555555555556, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788549, Length=266, Percent_Identity=25.9398496240602, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=245, Percent_Identity=27.7551020408163, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789403, Length=297, Percent_Identity=27.9461279461279, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1789149, Length=320, Percent_Identity=22.5, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=236, Percent_Identity=24.5762711864407, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52087; Mature: 52087

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFDRQQRQTSWLIVALSTLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKSSVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCCHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLHISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIVAAHSPFGGVSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC
>Mature Secondary Structure
MKFWRPGITGKLFLAIFATCIVLLITMHWAVRISFERGFIDYIKHGNEQRLQMLGDALGE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHCCCHHHHHHHHHHHHH
QYAQHGNWRFLRNNDRFVFQILRSLEHDNNEDKPGPGMPPHGWRTQFWVVDQNNKVLVGP
HHHHCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCEEEECC
RAPIPPDGTRRPIMVNGAEVGAVIASPVERLTRNTDINFDRQQRQTSWLIVALSTLLAAL
CCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ATFPLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
HHHHHHHHHHHHHHHHHCCHHHEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
SDEGALAYQKSSVDLIPLLEVAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNN
CCCCCEEEECCCCCHHHHHHHCCHHHHHHHHHCCCEEEEECCCCEEEECCHHHHHHHHHH
LLENSLRYTDSGGSLHISAEQHDKTVRLTFADSAPGVSDDQLQKLFERFYRTEGSRNRAS
HHHHCCEEECCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCC
GGSGLGLAICLNIVEAHNGRIVAAHSPFGGVSITVELPLERDLQREV
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]