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The map label for this gene is yeeF [H]

Identifier: 218549427

GI number: 218549427

Start: 2123526

End: 2124884

Strand: Reverse

Name: yeeF [H]

Synonym: EFER_2097

Alternate gene names: 218549427

Gene position: 2124884-2123526 (Counterclockwise)

Preceding gene: 218549428

Following gene: 218549426

Centisome position: 46.31

GC content: 52.02

Gene sequence:

>1359_bases
ATGTCGCATAACGTTACTCCAAACACCTCTCGCGTGGAATTGCGTAAAACGCTTACGTTAGTTCCGGTTGTAATGATGGG
TCTTGCCTATATGCAGCCGATGACGCTGTTTGATACATTTGGTATCGTTTCAGGCCTCACGGATGGTCATGTGCCGACAG
CCTATGCGTTCGCATTGATTGCGATCCTGTTTACGGCTCTGAGCTACGGGAAGCTGGTTCGCCGCTATCCTTCTGCTGGC
TCTGCATACACCTACGCCCAGAAATCCATTAGTCCGACTGTCGGCTTTATGGTGGGTTGGTCTTCTCTGCTCGACTATCT
GTTCGCGCCGATGATCAACATTCTGCTGGCGAAAATCTATTTTGAAGCTCTGGTGCCTTCCATCCCATCGTGGATGTTTG
TGGTGGCGCTGGTGGCCTTTATGACCGCCTTTAACCTGCGTAGTCTGAAATCCGTAGCGAACTTCAACACTGTAATTGTA
GTGTTGCAGGTAGTGCTGATCGCGGTAATTCTGGGCATGGTAGTTTACGGCGTATTTGAAGGTGAAGGCGCTGGTACGCT
GGCGAGCACTCGTCCGTTCTGGTCTGGTGATGCACATGTCATTCCGATGATCACTGGTGCGACGATTCTGTGCTTCTCCT
TTACCGGCTTTGACGGCATCAGCAACTTGTCGGAAGAAACCAAAGATGCAGAGCGCGTGATCCCGCGTGCAATTTTCCTG
ACCGCGCTTATCGGCGGCATGATCTTCATCTTTGCAACTTACTTCCTGCAACTGTACTTCCCGGATATCTCTCGTTTTAA
AGATCCGGAAGCATCACAGCCTGAAATCATGCTGTACGTTGCGGGTAAAACGTTCCAGGTTGGCGCGCTGATCTTCTCCA
CCATTACCGTACTGGCGTCCGGTATGGCGGCGCACGCAGGCGTGGCGCGTCTGATGTACGTAATGGGTCGTGACGGCGTA
TTCCCGAAAAGCTTCTTCGGTTATGTGCACCCGAAATGGCGTACTCCGGCAATGAACATCATCCTGGTTGGCGCGATTGC
CCTGCTGGCAATCAACTTTGACCTGGTAATGGCTACGGCGCTGATTAACTTTGGTGCGTTGGTGGCGTTCACCTTCGTTA
ACCTGTCGGTTATCTCGCAGTTCTGGATCCGTGAGAAGCGTAACAAGACGCTGAAGGATCACTTCCAGTATCTGTTCCTG
CCGATGTGTGGTGCGCTGACCGTTGGTGCGCTGTGGGTTAATCTGGAAGAAAGCTCAATGGTTCTGGGTCTGATCTGGGC
GGCAATCGGTCTGATTTACCTGGCTTGCGTAACTAAGAGCTTCCGTAACCCGGTTCCGCAGTACGAAGACGTAGCGTAA

Upstream 100 bases:

>100_bases
GATATTTACTAAAAATCGACAGTTGTTGTCGCTGAGGAATCCAAAAAAATGGGGCAATTTTTTGCTTACGCGACGGTTAT
TACCGTAAAGGAGAATGACC

Downstream 100 bases:

>100_bases
TCATCTTTTCTAATAATAAACCGGAGTCGAATGAATATTTGGCTCCGGTTTTTTTATTCTTTTTATCGAAATCCTCATTA
ATAACCATTTGTTCTAATTT

Product: amino-acid/amine transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAG
SAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFL
TALIGGMIFIFATYFLQLYFPDISRFKDPEASQPEIMLYVAGKTFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGV
FPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFL
PMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYEDVA

Sequences:

>Translated_452_residues
MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAG
SAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFL
TALIGGMIFIFATYFLQLYFPDISRFKDPEASQPEIMLYVAGKTFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGV
FPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFL
PMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYEDVA
>Mature_451_residues
SHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGS
AYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIVV
LQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFLT
ALIGGMIFIFATYFLQLYFPDISRFKDPEASQPEIMLYVAGKTFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVF
PKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFLP
MCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYEDVA

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=422, Percent_Identity=22.7488151658768, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI186910308, Length=415, Percent_Identity=23.6144578313253, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI186910306, Length=415, Percent_Identity=23.6144578313253, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI186910304, Length=415, Percent_Identity=23.6144578313253, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI181337167, Length=399, Percent_Identity=23.8095238095238, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082023, Length=452, Percent_Identity=99.5575221238938, Blast_Score=912, Evalue=0.0,
Organism=Escherichia coli, GI87081869, Length=446, Percent_Identity=63.4529147982063, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI87082250, Length=328, Percent_Identity=25, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790653, Length=352, Percent_Identity=23.2954545454545, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1786602, Length=265, Percent_Identity=24.5283018867925, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786789, Length=362, Percent_Identity=23.2044198895028, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788480, Length=339, Percent_Identity=21.8289085545723, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786302, Length=289, Percent_Identity=23.5294117647059, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=402, Percent_Identity=26.1194029850746, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17533459, Length=399, Percent_Identity=27.0676691729323, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17531343, Length=404, Percent_Identity=26.980198019802, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24667468, Length=408, Percent_Identity=26.9607843137255, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI221512776, Length=422, Percent_Identity=23.4597156398104, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24666159, Length=422, Percent_Identity=23.4597156398104, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24668806, Length=420, Percent_Identity=26.4285714285714, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356285, Length=420, Percent_Identity=26.4285714285714, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24668802, Length=420, Percent_Identity=26.4285714285714, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281366235, Length=352, Percent_Identity=24.7159090909091, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI116007820, Length=352, Percent_Identity=24.7159090909091, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI116007818, Length=352, Percent_Identity=24.7159090909091, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI85725152, Length=352, Percent_Identity=24.7159090909091, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49582; Mature: 49451

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIY
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIVVLQVVLIAVILGMVVYGVFE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFL
CCCCCCCCCCCCCCCCCCEEEEEHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
TALIGGMIFIFATYFLQLYFPDISRFKDPEASQPEIMLYVAGKTFQVGALIFSTITVLAS
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
GMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATA
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFLPMCGALTVGALWVNLEESSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHH
VLGLIWAAIGLIYLACVTKSFRNPVPQYEDVA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
AILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIY
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIVVLQVVLIAVILGMVVYGVFE
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFL
CCCCCCCCCCCCCCCCCCEEEEEHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
TALIGGMIFIFATYFLQLYFPDISRFKDPEASQPEIMLYVAGKTFQVGALIFSTITVLAS
HHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
GMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATA
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFLPMCGALTVGALWVNLEESSM
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCHH
VLGLIWAAIGLIYLACVTKSFRNPVPQYEDVA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]