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The map label for this gene is ydcV

Identifier: 218548872

GI number: 218548872

Start: 1553172

End: 1553966

Strand: Direct

Name: ydcV

Synonym: EFER_1517

Alternate gene names: 218548872

Gene position: 1553172-1553966 (Clockwise)

Preceding gene: 218548871

Following gene: 218548873

Centisome position: 33.85

GC content: 54.09

Gene sequence:

>795_bases
ATGCACTCTGAACGCGCACCGTTTTTCCTCAAACTGGCGGCCTGGGGCGGCGTGGTTTTCCTACATTTTCCCATCCTGAT
TATCGCCGCCTATGCGTTTAACACTGAAGATGCGGCGTTTAGCTTTCCACCGCAAGGCCTGACGCTGCGCTGGTTTAGCG
TGGCAGCACAGCGTAGTGATATTCTTGATGCCGTGACACTGTCACTTAAAGTGGCGGCGCTGGCGACATTAATTGCGCTG
GTATTAGGGACGCTGGCAGCTGCCGCGCTGTGGCGACGAGACTTTTTCGGCAAAAACGCCATTTCGTTGTTACTGCTGCT
GCCCATTGCGCTGCCGGGCATTGTCACTGGTCTGGCGCTATTAACCGCTTTTAAAACCATCAATCTGGAGCCGGGATTTT
TCACCATCGTGGTCGGTCATGCGACTTTTTGCGTAGTGGTGGTGTTTAACAATGTCATCGCCCGTTTTCGCCGCACCTCC
TGGAGTCTGGTTGAGGCGTCAATGGATCTTGGGGCCAATGGCTGGCAAACCTTCCGCTACGTAGTGTTGCCGAATCTCAG
TTCGGCGCTACTGGCAGGAGGAATGCTGGCGTTTGCCTTGTCGTTCGATGAAATCATCGTGACGACCTTTACGGCAGGTC
ATGAACGAACGTTACCGTTGTGGTTGCTCAATCAGCTTGGGCGACCACGTGATGTACCGGTAACAAACGTGGTGGCACTG
CTGGTTATGTTGGTAACAACCTTGCCGATCCTGGGAGCCTGGTGGCTAACCCGCGAAGGCGACAATGGTCAATAA

Upstream 100 bases:

>100_bases
GGGGCGATTGGCAATATGCCGATGGCGGCGGCATTCACCCTGGTGCCGATTGTTCTCATCGCACTGTACCTGGCGTTCGT
GAAACGTCTGGGAGCGTTCG

Downstream 100 bases:

>100_bases
CCACTGATACAGGAATATGCTATGCAACATAAGTTACTGATTAACGGAGAACTGGTTAGCGGCGAAGGGGAAAAACAGCC
TGTCTATAATCCGGCAACGG

Product: spermidine/putrescine ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPPQGLTLRWFSVAAQRSDILDAVTLSLKVAALATLIAL
VLGTLAAAALWRRDFFGKNAISLLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTLPLWLLNQLGRPRDVPVTNVVAL
LVMLVTTLPILGAWWLTREGDNGQ

Sequences:

>Translated_264_residues
MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPPQGLTLRWFSVAAQRSDILDAVTLSLKVAALATLIAL
VLGTLAAAALWRRDFFGKNAISLLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTLPLWLLNQLGRPRDVPVTNVVAL
LVMLVTTLPILGAWWLTREGDNGQ
>Mature_264_residues
MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPPQGLTLRWFSVAAQRSDILDAVTLSLKVAALATLIAL
VLGTLAAAALWRRDFFGKNAISLLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTLPLWLLNQLGRPRDVPVTNVVAL
LVMLVTTLPILGAWWLTREGDNGQ

Specific function: Probably part of the binding-protein-dependent transport system ydcSTUV; probably responsible for the translocation of the substrate across the membrane

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787714, Length=264, Percent_Identity=100, Blast_Score=519, Evalue=1e-149,
Organism=Escherichia coli, GI1787368, Length=234, Percent_Identity=29.0598290598291, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1787081, Length=256, Percent_Identity=31.25, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787080, Length=214, Percent_Identity=28.5046728971963, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YDCV_ECOLI (P0AFR9)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   F64896
- RefSeq:   AP_002066.1
- RefSeq:   NP_415960.1
- ProteinModelPortal:   P0AFR9
- SMR:   P0AFR9
- STRING:   P0AFR9
- EnsemblBacteria:   EBESCT00000001438
- EnsemblBacteria:   EBESCT00000015182
- GeneID:   945903
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1438
- KEGG:   eco:b1443
- EchoBASE:   EB3528
- EcoGene:   EG13765
- eggNOG:   COG1177
- GeneTree:   EBGT00050000008926
- HOGENOM:   HBG685300
- OMA:   ADGWQTF
- ProtClustDB:   CLSK880066
- BioCyc:   EcoCyc:YDCV-MONOMER
- Genevestigator:   P0AFR9
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 28722; Mature: 28722

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2904b808)-; HASH(0x2940d4ac)-; HASH(0x2938046c)-; HASH(0x2939ea90)-; HASH(0x2929f054)-; HASH(0x2909cfb0)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPPQGLTLRWFSVAAQRSD
CCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEHHHHHHHHHHH
ILDAVTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAISLLLLLPIALPGIVTGLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTSWSLVEASMDLGANGWQTFRY
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHEEEE
VVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTLPLWLLNQLGRPRDVPVTNVVAL
EEECCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHH
LVMLVTTLPILGAWWLTREGDNGQ
HHHHHHHHHHHHHHHEECCCCCCH
>Mature Secondary Structure
MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPPQGLTLRWFSVAAQRSD
CCCCCCCEEEEEHHHCCHHHHHHHHHHHHHHHCCCCCCCEECCCCCCEEHHHHHHHHHHH
ILDAVTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAISLLLLLPIALPGIVTGLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
LTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTSWSLVEASMDLGANGWQTFRY
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHEEEE
VVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTLPLWLLNQLGRPRDVPVTNVVAL
EEECCCHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHH
LVMLVTTLPILGAWWLTREGDNGQ
HHHHHHHHHHHHHHHEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503