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The map label for this gene is gst [H]

Identifier: 218548769

GI number: 218548769

Start: 1446970

End: 1447572

Strand: Reverse

Name: gst [H]

Synonym: EFER_1408

Alternate gene names: 218548769

Gene position: 1447572-1446970 (Counterclockwise)

Preceding gene: 218548770

Following gene: 218548763

Centisome position: 31.55

GC content: 48.26

Gene sequence:

>603_bases
ATGAAACTGTTTTACAAACCCGGCGCCTGTTCACTGGCTTCTCATATCACCCTTCGTGAGAGTGGTAAGGATTTCACTCT
GGAGTGTGTGGATTTACAGAACAAACGCCTGGAAAATGGCGATGACTACTTCGCTGTCAATCCAAAAGGTCAGGTTCCGG
CACTGCTGCTTGATGAAGGTGCGCTACTCACCGAAGGCGTTGCTATTATGCAATACCTGGCAGACCTTGTGCCTGATCAT
CAATTACTGGCCCCTGTTAATACCCTTGCCCGCCAGACCATCGAATGGCTGAATTACATTGCCACTGAGCTACACAAAGG
CTTCACGCCACTGTTTCGTCCTGATACACCGGAAGAGTTTAAGCCATCCGTGCGTGCGCAGCTTGAAAAGAAACTGCACT
ACATTGACGATGCGCTAAAAGATGACCAGTGGATTTGTGGCGCACGTTTCACCATTGCCGATGCTTACCTGTTCACAGTT
TTGCGTTGGGCATATGGCGTTAAGCTGAATATGGAAGGTTTAGATCATATCGCTTCATATATGACGCGAATGGCAGAACG
CCCGAAAGTTAAAGCGGCACTGTCAGCGGAAGGATTAAAGTAA

Upstream 100 bases:

>100_bases
AGGGAAACGCTTTTTTAAGCCGCTAACTTTGCGTTAGCGGCTTTTTTTTTACCCATTTGCGCACTACCATGATCTTTCAA
TCAGTCAAAAGGAGTTAGCG

Downstream 100 bases:

>100_bases
ACGTTAACGCCAGATGGCGAGATAAATCACTTATCCGGTTCTGTTGATGCACTCTCAGACCGGATAAGTGTTTTGAATAG
CGACAAAAATTAAAGCTGTG

Product: glutathionine S-transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKLFYKPGACSLASHITLRESGKDFTLECVDLQNKRLENGDDYFAVNPKGQVPALLLDEGALLTEGVAIMQYLADLVPDH
QLLAPVNTLARQTIEWLNYIATELHKGFTPLFRPDTPEEFKPSVRAQLEKKLHYIDDALKDDQWICGARFTIADAYLFTV
LRWAYGVKLNMEGLDHIASYMTRMAERPKVKAALSAEGLK

Sequences:

>Translated_200_residues
MKLFYKPGACSLASHITLRESGKDFTLECVDLQNKRLENGDDYFAVNPKGQVPALLLDEGALLTEGVAIMQYLADLVPDH
QLLAPVNTLARQTIEWLNYIATELHKGFTPLFRPDTPEEFKPSVRAQLEKKLHYIDDALKDDQWICGARFTIADAYLFTV
LRWAYGVKLNMEGLDHIASYMTRMAERPKVKAALSAEGLK
>Mature_200_residues
MKLFYKPGACSLASHITLRESGKDFTLECVDLQNKRLENGDDYFAVNPKGQVPALLLDEGALLTEGVAIMQYLADLVPDH
QLLAPVNTLARQTIEWLNYIATELHKGFTPLFRPDTPEEFKPSVRAQLEKKLHYIDDALKDDQWICGARFTIADAYLFTV
LRWAYGVKLNMEGLDHIASYMTRMAERPKVKAALSAEGLK

Specific function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787923, Length=201, Percent_Identity=84.5771144278607, Blast_Score=340, Evalue=4e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =2.5.1.18 [H]

Molecular weight: Translated: 22573; Mature: 22573

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFYKPGACSLASHITLRESGKDFTLECVDLQNKRLENGDDYFAVNPKGQVPALLLDEG
CCEEECCCCHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEECCC
ALLTEGVAIMQYLADLVPDHQLLAPVNTLARQTIEWLNYIATELHKGFTPLFRPDTPEEF
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KPSVRAQLEKKLHYIDDALKDDQWICGARFTIADAYLFTVLRWAYGVKLNMEGLDHIASY
CHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHH
MTRMAERPKVKAALSAEGLK
HHHHHHCCCHHHHHCCCCCC
>Mature Secondary Structure
MKLFYKPGACSLASHITLRESGKDFTLECVDLQNKRLENGDDYFAVNPKGQVPALLLDEG
CCEEECCCCHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEECCC
ALLTEGVAIMQYLADLVPDHQLLAPVNTLARQTIEWLNYIATELHKGFTPLFRPDTPEEF
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
KPSVRAQLEKKLHYIDDALKDDQWICGARFTIADAYLFTVLRWAYGVKLNMEGLDHIASY
CHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHH
MTRMAERPKVKAALSAEGLK
HHHHHHCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]