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The map label for this gene is bcsA [H]

Identifier: 218548531

GI number: 218548531

Start: 1200643

End: 1202748

Strand: Direct

Name: bcsA [H]

Synonym: EFER_1161

Alternate gene names: 218548531

Gene position: 1200643-1202748 (Clockwise)

Preceding gene: 218548530

Following gene: 218548532

Centisome position: 26.17

GC content: 41.64

Gene sequence:

>2106_bases
GTGAGTATAAAATATAAACCACATTATCATAAATTACTTCTGCTGGTTATTATAACGCTTTGTATAATCTTCATCTCGCT
GATTGAGCAACCACTTACTCTTTATCAACAGACGTTTTTTTCTGCCATTATTTGTCTTGCGGTCCTGCTGATCAATTTTG
GCAAAGGAAGATTTATTACGCTTTTCTTGATGGGTATCGGTATTTTGATCTCATCACGTTATATTTTCTGGCGGATTTCA
ACCACCTTAATATGGGATAAATATCCCGATATTTTCTTCTCGTTAACGCTACTGATTGCCGAGATCTATGCTTGGGCCGT
GTTACTGCTGGGTTATTTTCAGGTTTGTTTCCCGCTTAACCGTGAGAGCTTGCCATTGCCAGCAGATCCAACACACTGGC
CATCGGTGGATATTTTTATTCCAACCTATAATGAGCCGTTGTCAGTGGTGCAAAACACTGTTTATGGTGCATTAGCGATG
AACTGGCCAGAAGATAAAATCACCATCTGGTTATTAGATGACGGAGGTAGAGACGCGTTTCGCCGTTTTGCCGAGGAAAC
AGGAATTCGTTATGTAGCCAGAAGCACTCATGAACACGCGAAAGCAGGAAATATTAATCATGCGTTGAAGCTGGCGAAGA
GTGAATTTGTCGCTATTTTTGATTGCGACCATATTCCTTCGGTATCTTTTTTGCAGCGAACAATGGGCTGGTTTTTAGCC
GATGAAAAACTGGCGATGATGCAAACGCCACACCATTTTTTCTCTCCTGATCCTTTTGAAAGAAATTTAGGGAAATTTAG
ACAGAAACCTAATGAAGGTCATCTGTTTTATGGCTTGATTCAAAATGGTACTGATACGTGGAATGCCTCGTTCTTCTGTG
GCTCTTGCGCGGTTATCCGTCGTAAACCGTTGGATGAAATTGGTGGGATTGCCGTCGAAACGGTGACAGAAGATGCGCAT
ACATCTCTGCGTTTGCATCGTCTTGGCTACAGTTCAGCGTATTTGCGCTATCCATTAGCTGCTGGTCTTGCAACTGAAAC
ATTATCGGCACATATCGGGCAACGCATACGTTGGGCGCGCGGCATGATCCAAATTTTACGTATCGACAACCCGTTGTTGG
GAAAAGGCCTGCAACTATCTCAGCGTCTGTGTTATCTCAGCAGTATGATGCATTTTTTGTCAGGCGTACCACGACTAATT
TTTCTTTGTGCACCACTGTGCCCCATTTTTTTCTCCGTAGGGCTTATCGATGCTACTGTCACCGATATTATGTCCTATGT
TTTGCCGTATCTGTTTATTGTGGTATTAATTAATTCACGGATTCAGGGTAAGTACCGCCATTCATTCTGGAATGAAATTT
ATGAGATGGTGCTGGCCTGGTATATTACGCTACCGACACTGGTGGCACTAATTGCCCCGGCGAAAGGGCGTTTTAATGTC
ACTGCCAAAGGTGGATTGATCGCCAATAAATATGTGGACTGGCAGATCTCATACCCATACGTTATTTTTGCTATTTTGAA
TCTATGTGGTCTGATAGCAGGCATAATTCAGGTTAGTGAGTTAAATGGTGAAGCGGCACTGTTAAACACAATATGTTTAA
TGTGGCTGGTATATAACACTATTATTATTGGCGCAACGCTGGCAGTTTCTATTGAGCAAAAGCAAGTGCGTGTTTCGCCT
CGTATTGAGGTCGCGTTTAGTGGTCACTTGTTGCTGACGAATGGCACACGACACACTTGTTCGGTAATCGATTTTTCTGA
GGGAGGATTAGGTATCACGCTTCATAGCAGGCTGGGTAATCGGAATATCGAAAAAAATAAACCAATGACTTTATATTTAC
ATACTGGTGATGAGGAGTGCGCGATCCCTGTTGAAATTGTTCACGCGTTTAAAAATAAAATTGGTTTGAAAATATTGCCT
ATGACGCATAAAGAACATATCGATTATGTACGGGCAACTTTTTCGCGTGATAATCTCTGGAGTGACTGGCATAATAGCCT
TCCTCGCGACAAGATTTTAAAAAGCTTTTTGACTATTTGTTGGGTTTCTCTAAAAGGTTATTACCAGTTCTTATTATTTT
TAATTTCTCCGATGAAGAAGAAATGA

Upstream 100 bases:

>100_bases
AGAACGGCAGGGCACAGATTACCTGGCAATAATCTGTAAAAATGATGCCGAAATTGTTTCAAATCCGAAAGGAAGTCATT
TAAATCCAGGGCTAATTGAT

Downstream 100 bases:

>100_bases
CTATTTAATTTTTTCTGTGTTCATAAAGTCTCTTCACTGTAATTAGTTTTTAAGATTTCTGATAATGCTAAGAAAACTTT
TTTGCATCTATGCACTGGCA

Product: cellulose synthase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 700

Protein sequence:

>701_residues
MSIKYKPHYHKLLLLVIITLCIIFISLIEQPLTLYQQTFFSAIICLAVLLINFGKGRFITLFLMGIGILISSRYIFWRIS
TTLIWDKYPDIFFSLTLLIAEIYAWAVLLLGYFQVCFPLNRESLPLPADPTHWPSVDIFIPTYNEPLSVVQNTVYGALAM
NWPEDKITIWLLDDGGRDAFRRFAEETGIRYVARSTHEHAKAGNINHALKLAKSEFVAIFDCDHIPSVSFLQRTMGWFLA
DEKLAMMQTPHHFFSPDPFERNLGKFRQKPNEGHLFYGLIQNGTDTWNASFFCGSCAVIRRKPLDEIGGIAVETVTEDAH
TSLRLHRLGYSSAYLRYPLAAGLATETLSAHIGQRIRWARGMIQILRIDNPLLGKGLQLSQRLCYLSSMMHFLSGVPRLI
FLCAPLCPIFFSVGLIDATVTDIMSYVLPYLFIVVLINSRIQGKYRHSFWNEIYEMVLAWYITLPTLVALIAPAKGRFNV
TAKGGLIANKYVDWQISYPYVIFAILNLCGLIAGIIQVSELNGEAALLNTICLMWLVYNTIIIGATLAVSIEQKQVRVSP
RIEVAFSGHLLLTNGTRHTCSVIDFSEGGLGITLHSRLGNRNIEKNKPMTLYLHTGDEECAIPVEIVHAFKNKIGLKILP
MTHKEHIDYVRATFSRDNLWSDWHNSLPRDKILKSFLTICWVSLKGYYQFLLFLISPMKKK

Sequences:

>Translated_701_residues
MSIKYKPHYHKLLLLVIITLCIIFISLIEQPLTLYQQTFFSAIICLAVLLINFGKGRFITLFLMGIGILISSRYIFWRIS
TTLIWDKYPDIFFSLTLLIAEIYAWAVLLLGYFQVCFPLNRESLPLPADPTHWPSVDIFIPTYNEPLSVVQNTVYGALAM
NWPEDKITIWLLDDGGRDAFRRFAEETGIRYVARSTHEHAKAGNINHALKLAKSEFVAIFDCDHIPSVSFLQRTMGWFLA
DEKLAMMQTPHHFFSPDPFERNLGKFRQKPNEGHLFYGLIQNGTDTWNASFFCGSCAVIRRKPLDEIGGIAVETVTEDAH
TSLRLHRLGYSSAYLRYPLAAGLATETLSAHIGQRIRWARGMIQILRIDNPLLGKGLQLSQRLCYLSSMMHFLSGVPRLI
FLCAPLCPIFFSVGLIDATVTDIMSYVLPYLFIVVLINSRIQGKYRHSFWNEIYEMVLAWYITLPTLVALIAPAKGRFNV
TAKGGLIANKYVDWQISYPYVIFAILNLCGLIAGIIQVSELNGEAALLNTICLMWLVYNTIIIGATLAVSIEQKQVRVSP
RIEVAFSGHLLLTNGTRHTCSVIDFSEGGLGITLHSRLGNRNIEKNKPMTLYLHTGDEECAIPVEIVHAFKNKIGLKILP
MTHKEHIDYVRATFSRDNLWSDWHNSLPRDKILKSFLTICWVSLKGYYQFLLFLISPMKKK
>Mature_700_residues
SIKYKPHYHKLLLLVIITLCIIFISLIEQPLTLYQQTFFSAIICLAVLLINFGKGRFITLFLMGIGILISSRYIFWRIST
TLIWDKYPDIFFSLTLLIAEIYAWAVLLLGYFQVCFPLNRESLPLPADPTHWPSVDIFIPTYNEPLSVVQNTVYGALAMN
WPEDKITIWLLDDGGRDAFRRFAEETGIRYVARSTHEHAKAGNINHALKLAKSEFVAIFDCDHIPSVSFLQRTMGWFLAD
EKLAMMQTPHHFFSPDPFERNLGKFRQKPNEGHLFYGLIQNGTDTWNASFFCGSCAVIRRKPLDEIGGIAVETVTEDAHT
SLRLHRLGYSSAYLRYPLAAGLATETLSAHIGQRIRWARGMIQILRIDNPLLGKGLQLSQRLCYLSSMMHFLSGVPRLIF
LCAPLCPIFFSVGLIDATVTDIMSYVLPYLFIVVLINSRIQGKYRHSFWNEIYEMVLAWYITLPTLVALIAPAKGRFNVT
AKGGLIANKYVDWQISYPYVIFAILNLCGLIAGIIQVSELNGEAALLNTICLMWLVYNTIIIGATLAVSIEQKQVRVSPR
IEVAFSGHLLLTNGTRHTCSVIDFSEGGLGITLHSRLGNRNIEKNKPMTLYLHTGDEECAIPVEIVHAFKNKIGLKILPM
THKEHIDYVRATFSRDNLWSDWHNSLPRDKILKSFLTICWVSLKGYYQFLLFLISPMKKK

Specific function: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multic

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain [H]

Homologues:

Organism=Escherichia coli, GI87082284, Length=691, Percent_Identity=55.4269175108538, Blast_Score=810, Evalue=0.0,
Organism=Escherichia coli, GI1787259, Length=280, Percent_Identity=25.3571428571429, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003919
- InterPro:   IPR001173
- InterPro:   IPR009875 [H]

Pfam domain/function: PF00535 Glycos_transf_2; PF07238 PilZ [H]

EC number: =2.4.1.12 [H]

Molecular weight: Translated: 79731; Mature: 79599

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKYKPHYHKLLLLVIITLCIIFISLIEQPLTLYQQTFFSAIICLAVLLINFGKGRFIT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LFLMGIGILISSRYIFWRISTTLIWDKYPDIFFSLTLLIAEIYAWAVLLLGYFQVCFPLN
HHHHHHHHHHHCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RESLPLPADPTHWPSVDIFIPTYNEPLSVVQNTVYGALAMNWPEDKITIWLLDDGGRDAF
CCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEEECCCCCEEEEEEEECCCHHHH
RRFAEETGIRYVARSTHEHAKAGNINHALKLAKSEFVAIFDCDHIPSVSFLQRTMGWFLA
HHHHHHCCCHHHHHCCHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHC
DEKLAMMQTPHHFFSPDPFERNLGKFRQKPNEGHLFYGLIQNGTDTWNASFFCGSCAVIR
CCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHH
RKPLDEIGGIAVETVTEDAHTSLRLHRLGYSSAYLRYPLAAGLATETLSAHIGQRIRWAR
CCCHHHHCCEEEEEECCCHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMIQILRIDNPLLGKGLQLSQRLCYLSSMMHFLSGVPRLIFLCAPLCPIFFSVGLIDATV
HHHEEHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TDIMSYVLPYLFIVVLINSRIQGKYRHSFWNEIYEMVLAWYITLPTLVALIAPAKGRFNV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
TAKGGLIANKYVDWQISYPYVIFAILNLCGLIAGIIQVSELNGEAALLNTICLMWLVYNT
EECCCEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IIIGATLAVSIEQKQVRVSPRIEVAFSGHLLLTNGTRHTCSVIDFSEGGLGITLHSRLGN
HHHHHHHEEEEEHHEEEECCEEEEEEECEEEEECCCCCEEEEEEECCCCEEEEEECCCCC
RNIEKNKPMTLYLHTGDEECAIPVEIVHAFKNKIGLKILPMTHKEHIDYVRATFSRDNLW
CCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCH
SDWHNSLPRDKILKSFLTICWVSLKGYYQFLLFLISPMKKK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SIKYKPHYHKLLLLVIITLCIIFISLIEQPLTLYQQTFFSAIICLAVLLINFGKGRFIT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
LFLMGIGILISSRYIFWRISTTLIWDKYPDIFFSLTLLIAEIYAWAVLLLGYFQVCFPLN
HHHHHHHHHHHCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RESLPLPADPTHWPSVDIFIPTYNEPLSVVQNTVYGALAMNWPEDKITIWLLDDGGRDAF
CCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHEEECCCCCEEEEEEEECCCHHHH
RRFAEETGIRYVARSTHEHAKAGNINHALKLAKSEFVAIFDCDHIPSVSFLQRTMGWFLA
HHHHHHCCCHHHHHCCHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHC
DEKLAMMQTPHHFFSPDPFERNLGKFRQKPNEGHLFYGLIQNGTDTWNASFFCGSCAVIR
CCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEECCCHHHH
RKPLDEIGGIAVETVTEDAHTSLRLHRLGYSSAYLRYPLAAGLATETLSAHIGQRIRWAR
CCCHHHHCCEEEEEECCCHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMIQILRIDNPLLGKGLQLSQRLCYLSSMMHFLSGVPRLIFLCAPLCPIFFSVGLIDATV
HHHEEHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TDIMSYVLPYLFIVVLINSRIQGKYRHSFWNEIYEMVLAWYITLPTLVALIAPAKGRFNV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
TAKGGLIANKYVDWQISYPYVIFAILNLCGLIAGIIQVSELNGEAALLNTICLMWLVYNT
EECCCEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IIIGATLAVSIEQKQVRVSPRIEVAFSGHLLLTNGTRHTCSVIDFSEGGLGITLHSRLGN
HHHHHHHEEEEEHHEEEECCEEEEEEECEEEEECCCCCEEEEEEECCCCEEEEEECCCCC
RNIEKNKPMTLYLHTGDEECAIPVEIVHAFKNKIGLKILPMTHKEHIDYVRATFSRDNLW
CCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCCCCH
SDWHNSLPRDKILKSFLTICWVSLKGYYQFLLFLISPMKKK
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]